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PubMed · 9783216

Segment-based scores for pairwise and multiple sequence alignments.

B Morgenstern·W R Atchley·K Hahn·A Dress
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Abstract

In this paper, we discuss a novel scoring scheme for sequence alignments. The score of an alignment is defined as the sum of so-called weights of aligned segment pairs. A simple modification of the weight function used by the original version of the DIALIGN alignment program turns out to have a crucial advantage: it can be applied to both, global and local alignment problems without the need to specify a threshold parameter.

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Amino Acid SequenceAnimalsArtificial IntelligenceHumansMolecular Sequence DataProteinsSequence AlignmentSequence Homology, Amino AcidSoftwareComparative StudyJournal Article

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B Morgenstern, W R Atchley, K Hahn, A Dress. 1998. Segment-based scores for pairwise and multiple sequence alignments.. https://pubmed.ncbi.nlm.nih.gov/9783216/

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