Radiologic volumetry on a personal computer with a stereologic method.

Abstract

RATIONALE AND OBJECTIVES: There is no universally accepted way to estimate organ and tumor volumes, and manual tracing of the outline of an organ or tumor is tedious, time-consuming, and therefore not widely used. The authors developed a stereologic method for estimating organ and tumor volumes with a personal computer and evaluated its accuracy and efficiency with computed tomographic images. MATERIALS AND METHODS: CT images were obtained of a 200-cm3 phantom sphere, a normal liver, a normal spleen, a brain tumor, and a large abdominopelvic tumor. Volumes were estimated with a computer program developed on a personal computer. The estimated volumes were compared with those found with the manual tracing method, which was used as a standard of reference. The time to complete each procedure was recorded. RESULTS: When approximately 200 grid points were used, the volumes estimated with the computer were varied from the reference by 1.9%-4.5%. The volumes ranged from 51 to 2,679 cm3, and the time to estimate these ranged from 42 to 96 seconds. CONCLUSION: Stereologic estimation of organ and tumor volumes from cross-sectional images with a personal computer can be accurate and efficient at a relatively low cost.