Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy.

G Zhu; X Kong; K Sze

doi:10.1006/jmre.1998.1558

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Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy.

G Zhu·X Kong·K Sze

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Abstract

A gradient- and sensitivity-enhanced HMQC experiment has been developed. The sensitivity of the experiment is increased by factors of the square root of 2 and 2 over the conventional and gradient-enhanced HMQC experiments, respectively. This improvement is achieved by retaining both the x and the y magnetization components in the indirectly detected dimension. This experiment will be particularly useful in NMR studies of large biomolecules as the relaxation time of the multiple-quantum coherence is much longer than that of the single-quantum coherence in the slow motion limit.

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Calmodulin Image Enhancement Models, Molecular Nuclear Magnetic Resonance, Biomolecular Protein Binding Protein Conformation Sensitivity and Specificity Comparative Study Journal Article Research Support, Non-U.S. Gov't

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G Zhu, X Kong, K Sze. 1998. Gradient- and sensitivity-enhanced heteronuclear multiple-quantum correlation spectroscopy.. https://doi.org/10.1006/jmre.1998.1558

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