[Experimentally induced actin depolymerization disrupts the adaptive state of a neuron].

L L Pavlik; N R Tiras; D A Moshkov

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PubMed · 9826813

[Experimentally induced actin depolymerization disrupts the adaptive state of a neuron].

L L Pavlik·N R Tiras·D A Moshkov

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Abstract

The state of filament actin in Mauthner neuron (MN) of gold-fish adapted to long-term natural stimulation was investigated after introduction of actin-depolymerizing cytochalasin D. Cytochalasin was demonstrated to cause almost complete disappearance of long actin bundles that were characteristic for the cytoplasm of adapted fish and were absent from MN of intact fish. Polymeric actin supporting the cytoskeleton integrity was suggested to be involved in mechanisms underlying the increase of MN resistance extreme loads.

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Actins Adaptation, Physiological Animals Cytochalasin D DNA Goldfish Neurons Nucleic Acid Synthesis Inhibitors Physical Stimulation Pons Vestibule, Labyrinth Comparative Study English Abstract Journal Article

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L L Pavlik, N R Tiras, D A Moshkov. 1998. [Experimentally induced actin depolymerization disrupts the adaptive state of a neuron].. https://pubmed.ncbi.nlm.nih.gov/9826813/

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