How important is Nramp1 in tuberculosis?

R J North; E Medina

doi:10.1016/s0966-842x(98)01364-x

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PubMed · 9846361

How important is Nramp1 in tuberculosis?

R J North·E Medina

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Abstract

The assumption that the antimicrobial resistance gene Nramp1 is a major determinant of resistance of mice to infection with virulent Mycobacterium tuberculosis can now be challenged on the basis of published evidence to the contrary. It is likely that, with tuberculosis, Nramp1-determined defenses are subordinate to other defenses.

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Animals Carrier Proteins Cation Transport Proteins Humans Immunity, Innate Macrophages Membrane Proteins Mice Mycobacterium bovis Mycobacterium tuberculosis Tuberculosis Natural Resistance-associated Macrophage Protein 1 Journal Article Research Support, U.S. Gov't, P.H.S.Review

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R J North, E Medina. 1998. How important is Nramp1 in tuberculosis?. https://doi.org/10.1016/s0966-842x(98)01364-x

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