SCOP: a Structural Classification of Proteins database.

T J Hubbard; B Ailey; S E Brenner; A G Murzin; C Chothia

doi:10.1093/nar/27.1.254

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SCOP: a Structural Classification of Proteins database.

T J Hubbard·B Ailey·S E Brenner·A G Murzin·C Chothia

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Abstract

The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known proteins structures. The classification is on hierarchical levels: the first two levels, family and superfamily, describe near and far evolutionary relationships; the third, fold, describes geometrical relationships. The distinction between evolutionary relationships and those that arise from the physics and chemistry of proteins is a feature that is unique to this database, so far. The database can be used as a source of data to calibrate sequence search algorithms and for the generation of population statistics on protein structures. The database and its associated files are freely accessible from a number of WWW sites mirrored from URL http://scop. mrc-lmb.cam.ac.uk/scop/

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Algorithms Databases, Factual Evolution, Molecular Information Storage and Retrieval Internet Protein Conformation Protein Folding Proteins Sequence Alignment Sequence Homology, Amino Acid Statistics as Topic Journal Article Research Support, Non-U.S. Gov't

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T J Hubbard, B Ailey, S E Brenner, A G Murzin, C Chothia. 1999-01-01. SCOP: a Structural Classification of Proteins database.. https://doi.org/10.1093/nar%2F27.1.254

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