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PubMed · 9869111

DNA vaccines: application to tuberculosis.

K Huygen
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Abstract

Since the first observations in the early 1990s, the scientific literature on DNA vaccines has been growing exponentially. This article reviews the history and general principle, summarizes current knowledge on immune mechanisms, discusses safety considerations and highlights possible advantages of this technique as compared to the classic vaccines. Special emphasis is placed on the potential of DNA vaccines with respect to tuberculosis.

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Adjuvants, ImmunologicAnimalsAntigens, BacterialBacterial VaccinesDNA, BacterialHeat-Shock ProteinsHumansMajor Histocompatibility ComplexMycobacterium tuberculosisPlasmidsTuberculosisVaccines, DNAJournal ArticleResearch Support, Non-U.S. Gov'tReview

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K Huygen. 1998. DNA vaccines: application to tuberculosis.. https://pubmed.ncbi.nlm.nih.gov/9869111/

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