Severe atypical endometrial changes and sequential contraceptive use.

R H Kaufman; K O Reeves; C M Dougherty

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PubMed · 988889

Severe atypical endometrial changes and sequential contraceptive use.

R H Kaufman·K O Reeves·C M Dougherty

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Abstract

Of eight young women, seven had a diagnosis of well-differentiated endometrial adenocarcinoma and one had atypical endometrial hyperplasia. The average age was 40.1 years, with 6.04 years of dimethisterone-ethinyl estradiol (Oracon) sequential contraceptive use. The patients were not typical of those in whom endometrial carcinoma develops. Although these cases do not prove that long-term administration of dimethisterone-ethinyl estradiol causes endometrial adenocarcinoma or atypia, they indicate that it may do so.

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Adenocarcinoma Adult Age Factors Dimethisterone Endometrial Hyperplasia Ethinyl Estradiol Female Humans Hysterectomy Middle Aged Parity Time Factors Uterine Neoplasms Journal Article

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R H Kaufman, K O Reeves, C M Dougherty. 1976-08-23. Severe atypical endometrial changes and sequential contraceptive use.. https://pubmed.ncbi.nlm.nih.gov/988889/

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