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Do redundant visual and auditory target variables facilitate control behavior?

The compensatory tracking paradigm has been used extensively in pioneering work on Control Theory, a cybernetic model of behavior. In most studies subjects have been asked to control or maintain at a steady state a single variable or aspect of the stimulus display. The present study utilized three groups of subjects, comparing their performance effectiveness in controlling: (1) a visual stimulus (cursor) versus (2) an auditory stimulus (tone) versus (3) a combined, redundant-cue condition employing both cursor and tone. Freshman volunteers responded to a computer display using a joystick controller; their task was to keep stationary a stimulus that was subject to a smoothed, quasirandom disturbance. Contrary to predictions, subjects in the cursor-alone group performed more effectively than subjects in the combined cursor-tone group. While speculative interpretations are offered, further research is needed to clarify these results.

Adolescent↗

Smoking and weight control behaviors.

OBJECTIVE: To examine the association between weight control and tobacco use in young women. METHODS: Smoking status and weight and eating related issues, endorsement of the belief "smoking helps to control weight" dieting status (DEBQ-R), current and ideal weight and current height were assessed in 144 students. RESULTS: Smoker (S) restrained eaters (RE) scored higher on dietary restraint than nonsmoker (NS) RE. In the smoking questionnaire, S-RE selected a significantly higher number of items concerning hunger, eating and weight than S unrestrained eaters (URE). S-RE had a greater level of endorsement of the belief: "smoking helps to control weight" than NS-URE. The subjects who marked those items had significantly higher scores in the DEBQ-R and were more likely to be RE than those who marked none of them. CONCLUSION: Our findings suggest that among young women who smoke and diet there might be a risk group that smokes as a weight control strategy.

Adolescent↗

Effects of thyrotropin-releasing hormone (TRH) and MK-771 on schedule-controlled behavior of squirrel monkeys, rabbits and pigeons.

The effects of TRH (0.001-10.0 mg/kg) and a more potent TRH analog, MK-771 (0.001-5.6 mg/kg), were studied on comparable schedule-controlled performances of squirrel monkeys, rabbits and pigeons. Responding was maintained in the presence of different stimuli by a multiple fixed-ratio (FR), fixed-interval (FI) schedule of food presentation (monkeys and pigeons) or 0.25% saccharin solution (rabbits). Generally, TRH and MK-771 produced decreases in responding under both schedules and in all three species. TRH and MK-771 were roughly equipotent in the squirrel monkey, whereas in the pigeon and rabbit MK-771 was approximately 20 times more potent than TRH in decreasing responding to 50 percent of control levels. The duration of action of doses of TRH and MK-771 that reduced responding to 50 percent of control was approximately 3 hr in the squirrel monkey; recovery of performance occurred twice as fast under the FR schedules. With the pigeon, TRH effects that produced 50 percent decreases in responding lasted over 6 hours, whereas behaviorally comparable doses of MK-771 lasted about 4 hours. With few exceptions, TRH and MK-771 appear to produce similar effects of schedule-controlled behavioral performances of the squirrel monkey, rabbit and pigeon. Compared to the effects of other behaviorally-active substances under these procedures, TRH and MK-771 exert a distinctive array of effects.

Animals↗

Time acts as a conditioned stimulus to control behavioral sensitization to amphetamine in rats.

Repeated exposure to the psychostimulant drug, amphetamine, results in a persistent increase in the ability of the drug to elicit behavioral activation.(14,19) The development of sensitized responses to amphetamine involves long-lasting neuroadaptations within defined circuitry.(3,6,12,15,23) The behavioral expression of sensitization, however, can come under the control of specific environmental cues. Thus, the sensitized locomotor response to a challenge injection of amphetamine is greater if the drug is given in the environment previously associated with intermittent injections than if given in a different environmental context.(2,13,16,18,20,21) Contrary to the wealth of information on the significance of contextual cues, little is known about the importance of time cues in the expression of sensitized responding to amphetamine. In the present study we, therefore, asked whether time of injection might influence the expression of amphetamine sensitization. We found that time can readily act as a conditioned stimulus to control the expression of behavioral sensitization to amphetamine in rats. This finding is important for understanding the mechanisms underlying sensitization to psychostimulant drugs and its impact on behavior.

Amphetamine↗

Species diversity and the evolution of behavioral controlling mechanisms.

One of the first things that we are impressed by is the great variety of animals, particularly their behaviors and their physiologies. With so many differences, are there any generalities? With the establishment of evolutionary theory, evidence of "unity in diversity" comes with discoveries of common anatomical features, the cell cycle, conservation of intermediary metabolism, and the genetic code, to name but a few. In vertebrates there appears to be a conservation of the neural circuits underlying sexual behavior, but it is still too early to state the extent to which this concept can be extended to the hormonal mechanisms underlying behavior. Much of our conceptual understanding of behavioral neuroendocrinology stems from extensive studies on relatively few species. When an evolutionary perspective is applied to behavioral neuroscience, the breadth and validity of our assumptions about the mechanisms that control species-typical behaviors are challenged. This is not the same thing as saying that there are few unitary explanations that apply to all mammals, amniotes, or even vertebrates. Considerable information has been gathered about the neuroendocrine bases of behavior in a few species, but to uncover truly broad generalizations, we must look with equal intensity and rigor at other organisms. The pattern of evolution is best illustrated in the diversity of organisms, and the ecological and evolutionary perspective illuminates the utility of various "experiments of nature." By studying (1) closely related species that live in different habitats, we can see if the adaptational responses are similar, and (2) distantly related species that live in the same habitat, we can see if the solutions are analogous. The unique qualities of each species also give us a deeper understanding of the constraints in fundamental processes. When basic conflicts exist, control mechanisms adapt or the species goes extinct. Interestingly, although the neural circuits themselves do not degenerate, they are either no longer used or coopted for other functions.

Animals↗

The effect of first aid training on Australian construction workers' occupational health and safety motivation and risk control behavior.

METHOD: A 24-week experiment was conducted to assess how first aid training affects the motivation of small business construction industry employees in avoiding occupational injuries and illnesses and its effect on their occupational health and safety behavior. A simplified multiple baseline design across workplace settings was used to evaluate the effects of first aid training. Participants' motivation to control occupational safety and health risks was explored during in-depth interviews before and after receipt of first aid training. Objective measurement of occupational safety and health behavior was conducted by a researcher directly observing the workplace before and after participants received first aid training. RESULTS: The observations at participants' worksites suggested that, for the most part, the first aid training had a positive effect on the occupational safety and health behavior of participants. First aid training appeared to reduce participants' "self--other" bias, making them more aware that their own experience of occupational safety and health risks is not beyond their control but that their own behavior is an important factor in the avoidance of occupational injury and illness. First aid training also appeared to reduce participants' willingness to accept prevailing levels of occupational safety and health risk and increase the perceived probability that they would suffer a work-related injury or illness. Participants expressed greater concern about taking risks at work after receiving first aid training. IMPACT ON INDUSTRY: It appears that first aid training enhances participants' motivation to avoid occupational injuries and illnesses and improves their risk control behavior. The implications of this are that first aid training can have a positive preventive effect and could complement traditional occupational health and safety training programs. As such, there may be benefit in providing first aid training to all employees rather than limiting this training to a small number of designated "first aiders."

Accident Prevention↗

Long-term central 5-HT depletions resulting from repeated administration of MDMA enhances the effects of single administration of MDMA on schedule-controlled behavior of rats.

The behavioral effect of single administration of +/- 3,4-methylene-dioxymethamphetamine (MDMA) on rats performing on the differential-reinforcement-of-low-rate 72-second schedule (DRL 72-sec) was compared before and after a period of repeated administration of MDMA known to deplete 5-hydroxytryptamine (5-HT) levels in the brain. Single administration of MDMA decreased reinforcement rate (1, 2, 4, 6 mg/kg) and increased response rate (4,6 mg/kg) of rats performing on the DRL 72-sec schedule. This effect is typical of amphetamines and other psychomotor stimulants. Four weeks after repeated administration of MDMA (6 mg/kg twice daily for 4 days) there was an increase in sensitivity to the effect of single administration of MDMA. Doses of 2, 4 and 6 mg/kg of MDMA resulted in increases in response rate that were significantly greater after repeated MDMA administration than before. Doses of 0.5, 2, and 6 mg/kg of MDMA resulted in decreases of reinforcement rate that were significantly greater after repeated MDMA administration than before. Repeated administration of MDMA resulted in long-term depletion of serotonin levels by 30-50% in the amygdala, neostriatum, hippocampus and the frontal cortex. Norepinephrine and dopamine (DA) levels were not significantly different from control in any of the brain regions analyzed. The behavioral and neurochemical results suggest that serotonergic neurons normally exert an inhibitory action upon the psychomotor stimulant effects of MDMA. Since the psychomotor stimulant effects of amphetamines appear to be mediated primarily by the dopamine system, these results provide evidence that 5-HT and DA may represent opposing systems in the DRL schedule-controlled behavior.

3,4-Methylenedioxyamphetamine↗

Afferent signaling and forebrain mechanisms in the behavioral control of extracellular fluid volume.

The body defends against reduced extracellular fluid volume both by activation of autonomic and endocrine reflexes and by mobilization of behavioral mechanisms. The behaviors that are required to correct an extracellular fluid deficit involve the ingestion of both water and sodium. It is reasonable to hypothesize that afferent neural input from both arterial and cardiopulmonary high pressure and volume receptors, and afferent humoral input in the form of ANG II, are important systemically-generated signals acting as afferent mediators of extracellular depletion-induced thirst and sodium appetite. Neural information from these signals has been shown to converge on forebrain structures located along the lamina terminalis where processing and integration of this input is likely to take place. This paper describes an analysis of the mechanisms of afferent signaling that accompanies a form of rapidly induced sodium appetite. Because volume and pressure-related input in concert with elevated activity of the renin-angiotensin system is likely to be important for generating this form of induced hypertonic sodium chloride and water intake, we have focused on the structures of the lamina terminalis, specifically the SFO, MnPO, and OVLT. Investigations that employ immunocytochemical methods for the detection of the early oncogene, c-fos, indicate that neurons in the lamina terminalis, as well as the SON and PVN, are activated by the composite of systemically derived signals necessary for producing thirst and sodium appetite. So far, there is no thorough understanding of how these visceral signals activate the neural substrates for these motivated behaviors. However, these studies, combining both functional and neuroanatomical approaches, provide a strategy for investigating the neurobiological basis of the behavioral and physiological control systems that maintain fluid balance and cardiovascular homeostasis. This paper describes an analysis of the mechanisms of afferent signaling that accompanies a form of rapidly induced sodium appetite. Because volume and pressure-related input, in concert with elevated activity of the renin-angiotensin system, is likely to be important for generating this form of induced hypertonic sodium chloride and water intake, we have focused on the structures of the lamina terminalis, specifically the SFO, MnPO, and OVLT. Investigations that employ immunocytochemical methods for the detection of the early oncogene, c-fos, indicate that neurons in the lamina terminalis, as well as the SON and PVN, are activated by the composite of systemically derived signals necessary for producing thirst and sodium appetite. So far, there is no thorough understanding of how these visceral sensory-related signals activate the neural substrates for these motivated behaviors.(ABSTRACT TRUNCATED AT 400 WORDS)

Afferent Pathways↗

Psychomotor stimulant effects of d-amphetamine, MDMA and PCP: aggressive and schedule-controlled behavior in mice.

The objective of the present experiments was to characterize psychomotor stimulant effects of d-amphetamine, methylenedioxymethamphetamine (MDMA) and phencyclidine (PCP) on conditioned performance and on aggressive behavior in mice. In a novel protocol with alternating periods of schedule-controlled responding and aggressive behavior toward an intruder it was possible to assess a range of species-specific agonistic acts, postures, and motor activities as well as response rates and patterns engendered by a multiple Fixed Interval (FI) and Fixed Ratio (FR) schedule within the same animal. Initially, it was confirmed that d-amphetamine and, less reliably, MDMA and PCP, increased FI, but not FR responding in mice. In the next experiment, mice confronted an intruder at the midpoint of the 1-h daily session; following the display of aggressive behavior, the rate of FI responding showed an amphetamine-like increase, whereas only a transient change occurred after non-aggressive encounters. Thirdly, using this new protocol, PCP, d-amphetamine and MDMA altered FI and FR responding in a way that was closely similar to the first experiment. Low PCP and d-amphetamine doses increased aggressive behavior erratically in certain individuals, but not reliably for the group. MDMA dose-dependently decreased aggressive behavior, and all drugs disrupted aggressive behavior at higher doses. The characteristic increases in walking and decreases in rearing after higher doses of PCP and d-amphetamine were greatly attenuated when the intruder was present.(ABSTRACT TRUNCATED AT 250 WORDS)

Aggression↗

Orogastric, hydrational, and behavioral controls of drinking following water deprivation in rats.

Drinking and its associated behaviors were studied in rats deprived of fluid for 8,24, or 48 hr. The behavior of rats drinking water could be divided into three successive stages: (a) an initial intense burst of drinking that could not be easily disrupted; (b) intermittent drinking, often distinguished by the brief appearance of conflict behavior directed at the drinking spout; and (c) termination of drinking. Drinking stopped well before the fluid loss, reflected in a sizable extracellular deficit, was restored. Intake of water was terminated when serum hyponatremia and hypoosmolality (and presumably cellular overhydration) developed in temporal continguity with drinking. These and other considerations suggest that the cellular fluid phase exerts significant inhibitory as well as excitatory control over drinking.

Animals↗