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PubMed1992

[Malignant cystosarcoma phyllodes].

The authors deal with the clinical and pathological aspects and histopathological criteria of malignity of cystosarcoma which are important from the aspect of assessment of the extent and type of surgical intervention. Large malignant cystosarcomas and cystosarcomas taking up the whole breast with damage of the skin are indicated for simple mastectomy, while small malignant cystosarcomas (i. e. in relation to the size of the breast) can be treated by a wide local excision with a safety margin, as some primary as well as recurrent phylloid tumours behave in a benign way or may transform into a fibroadenoma or a dysplastic focus. Moreover contrary to carcinoma of the breast, there is no association with a multicentric character of the disease. Axillary lymph nodes are only rarely affected; therefore dissection of the nodes is not necessary.

Adult↗
PubMed1991

[Cystosarcoma phyllodes].

A rare case of mammary neoplasia is described. Its morphological and cytologic features are ascribed to cystosarcoma phylloides. It's a rare neoplasia since it represents only the 0.3-0.9% of mammary tumors. At present about one thousand of case have been described in literature. Because of its unforeseeable behaviour, cystosarcoma phylloides requires treatment and follow-up different from mammary carcinoma and fibroadenomas. The treatment is surgical only; the choice between an extensive exeresis and a complete mastectomy is related to tumor dimensions.

Breast Neoplasms↗
PubMed1993

[Cystosarcoma phyllodes of the breast: clinical cases].

The authors report their experience in the management of 8 cases of cystosarcoma phylloides of the breast observed between January 1979 and December 1986 in the Surgical Department of the University of Bari. This uncommon breast pathology, which stands halfway between benign (adenofibromas) and malignant (carcinomas) tumors presents considerable difficulties in terms of diagnosis particularly problematic for the small-sized lesions. The authors stress the need of a surgical treatment which takes into account women aesthetic desire assuring at the same time a complete exeresis. The latter includes the sacrifice of at least 1 cm thick normal breast tissue to prevent the frequent local relapses.

Aged↗
PubMed1986

[Potential malignancy of cystosarcoma phyllodes of the breast. A contribution to the histogenesis of fibrosarcoma].

The present case report, which describes the transformation of a cystosarcoma phylloides into a "borderline case" and subsequently a fibrosarcoma, makes it clear that fibrosarcoma of the breast cannot always be regarded as a tumor which has developed primarily from mesenchymal breast tissue. Just as a benign cystosarcoma can turn malignant if therapy is inadequate, it can also turn into a purely sarcomatous tumor. The clinical consequences of this are that a cystosarcoma should not only be shelled out, but excised generously, with a wide border of healthy tissue. The "borderline" type of cystosarcoma phylloides, or respectively the fibrosarcoma, requires far more aggressive therapy, i.e., mastectomy. In fibrosarcoma cases additional selective lymphadenectomy may be considered, although the metastasization pattern is predominantly hematogenic. Overall, however, the prognosis for fibrosarcoma cases is better than for those with breast cancer.

Adipose Tissue↗