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Temporal consistency of the WAIS-R Memory/Freedom from Distractibility factor in a nonclinical sample.

The temporal consistency of the WAIS-R Memory/Freedom from Distractibility factor and its intrafactorial components were measured over a 4-wk. period in a nonclinical sample of 22 undergraduates. A modest but significant consistency coefficient of .49 was obtained for Memory/Freedom from Distractibility. Neither intrafactorial component manifested significant temporal consistency over four weeks. Significant retest improvements were expected and observed on Memory/Freedom from Distractibility and Advanced Computation. These retest improvements were interpreted in terms of task familiarity rather than specific content recall. The reported temporal consistency coefficients appear to represent the lowest consistency for these neuropsychological constructs. The routine use of Memory/Freedom from Distractibility was questioned pending more comprehensive measurement of reliability.

Adult↗

Developmental changes in consistency of preferential feeling for peers and objects around age four.

When do young children come to have an individual mental image of each peer? Forming a stable impression of each person requires maturation of at least two cognitive abilities, inferring the other's mind and episodic memory. According to past studies, the critical period for both these abilities is around age four. Thus, it was hypothesized that the child begins to form a consistent mental image of each peer at or after age four. To test this hypothesis, the temporal consistency of preference for peers was examined in 3-, 4-, and 5-yr.-olds. Each subject was asked "Who do you like better than others in this class?" once a week for three times (Study 1). The results indicated that most of the 3-yr.-olds answered different names as their favorite friends or nonsense things inconsistently week by week, whereas older children tended to answer the same names across weeks. However, changing the question to "Which object do you like best of these alternatives?" dramatically changed the response pattern (Study 2): preferences among nonhuman objects (playthings) were temporally consistent even for 3-yr.-olds. These results indicate that children before age four do have a temporally consistent feeling toward general objects but do not have a consistent firm feeling about personal relationships among peers. The results are discussed in relation to the critical developmental changes about age 4 in other cognitive abilities.

Attention↗

Altered ruminal mat consistency by high percentages of soybean hulls fed to lactating dairy cows.

Three ruminally fistulated dairy cows in early lactation were used in a 3 x 3 Latin square design with 3-wk periods to investigate the effects of alteration of ruminal mat consistency on ruminal function and soybean hull rate of passage. The control diet consisted of 60% forage (alfalfa:corn silages, 1:1, dry basis) and no soybean hulls. Replacement of 40% of the silage mixture with soybean hulls decreased ruminal mat consistency by 57% at 6 h postfeeding and reduced rumination activity 52%, ruminal pH 6%, and acetate:propionate ratio observed over 24 h by 10% compared with the control diet. Replacement of 75% of the silage with 25% soybean hulls combined with 20% coarsely chopped alfalfa hay increased ruminal mat consistency by 49% at 2 and 6 h postfeeding, increased the percentage of large particles (> or = 9.50 mm) retained in the dorsal rumen, and significantly increased ruminal pH 1.5% and acetate:propionate ratio by 17% compared with the diet of 25% soybean hulls without alfalfa hay. Increasing the ruminal mat consistency with coarsely chopped alfalfa hay did not significantly decrease the rate of escape of soybean hulls from the rumen, but addition of alfalfa hay increased 4% FCM 4.8 kg/d compared with FCM of diets containing 25% soybean hulls without alfalfa hay.

Animal Feed↗

Consistent contrast aids concept learning.

We suggest that coherence among concepts and correspondence between concepts and the world are important in concept learning. We identify one aspect of coherence, consistent contrast, and investigate its role in supervised concept learning. Concepts that contrast consistently carry information about the same attributes across the concepts within a contrast set. Concepts that contrast inconsistently predict and are predicted by values of different attributes. Experiment 1 revealed a large advantage for consistent contrast in learning and generalization. Experiment 2 pitted similarity against consistency and still revealed an advantage of consistency. Experiment 2 also broadened the range of tasks considered to include inductions about novel categories and subjects' category descriptions. We discuss relations to theories of concept learning, to attentional mechanism, and to alignability, and we suggest practical implications.

Adult↗

A phoneme-grapheme feedback consistency effect.

Recent studies examining the feedback consistency effect have been criticized for poor item selection (Peereman, Content, & Bonin, 1998). In the present study, an experiment was run with a new set of items, in which feedback consistency was manipulated at a phoneme-grapheme level. The results suggested that participants responded faster to feedback-consistent words than to feedback-inconsistent words. This was despite the feedback-consistent and feedback-inconsistent word groups' being matched on many other dimensions, including word frequency and subjective orthographic frequency. These results may differ from those of previous studies, since previous studies in English have measured feedback consistency at the rime-body level.

Choice Behavior↗

[A comparative study of consistent and inconsistent contraceptive users on partner communication, perceived contraceptive control, and sexual autonomy].

PURPOSE: This study is to investigate the influencing factors in the consistent use of contraception methods by comparing consistent and inconsistent users on partner communication, contraceptive control perception, and sexual autonomy among married Korean women. METHOD: This study consists of 243 married women living in Korea. A convenient sampling technique was used and data were collected by self report questionnaires from September 14, 2000 to October 20, 2000. RESULT: Only 41.6% of women were using contraception methods consistently and the rest of them were using contraception methods inconsistently. Between the two groups, statistical significances were noted in sexual communication(t=-2.5, p=.01), perceived contraceptive control(t=-7.5, p=.00) and sexual autonomy(t=-3.1, p=.00). As for general communication, it was not statistically significant(t=-1.0, p=.31). CONCLUSION: Family planning program advisors should recognize that intervention programs for the promotion of consistent contraceptive behavior should focus on the sexual communication, perceived contraceptive control, and sexual autonomy.

English Abstract↗

A simulation study of the consistency of oscillometric blood pressure measurements with and without artefacts.

BACKGROUND: Oscillometric pressure is measured by analysing, in relation to the cuff pressure, low-amplitude cuff-pressure pulsations generated by each arterial pulse. The cuff pressure is sampled at the pulse rate, introducing measurement variations, which are compounded by artefactual pulses. OBJECTIVE: To study the consistency of measurements with and without artefacts using simulated waveforms. METHODS: The Propaq Smartcuf (with and without electrocardiographic synchronization), the Welch Allyn 52 000 (before and after its software had been upgraded), the Critikon DINAMAP 8100 and Compact TS and the Criticare 507 NJC were evaluated. Each monitor recorded 15 determinations at 120/80 (93) mmHg without and with either low-frequency or high-frequency artefacts generated by the Bio-Tek BP-Pump simulator. Consistency of measurements was defined as SD of less than 2 mmHg for at least two of the systolic, diastolic and mean arterial pressures with all less than 3 mmHg. RESULTS: All monitors except the Critikon 8100 satisfied the consistency criteria without artefacts with most SD less than 1 mmHg. Several satisfied the criteria with a severe low-frequency artefact (all recorded SD were less than 6 mmHg). None satisfied the criteria with a severe high-frequency artefact. High systolic blood pressures were typically recorded with a severe tremor artefact, though the Criticare device, which measures during cuff inflation, recorded lower systolic blood pressures. The Propaq device with electrocardiographic synchronization had the lowest variability, with synchronization increasing determination time. CONCLUSION: Oscillometric monitors are more sensitive to a high-frequency artefact than they are to a low-frequency artefact. Signal-processing techniques can improve consistency of measurements. Simulators can evaluate a monitor's consistency with and without artefacts.

Blood Pressure Determination↗

Dynamic effects of food consistency on chewing motions.

The purpose of the study was to find evidence of how different types of food consistency affect chewing motions, especially the forward, downward and sidewise extents of motion of the lower jaw. Nineteen individuals with intact tooth sequence, aged from 20 to 37 years, were asked to chew three types of food of different consistency (banana, bread, carrot). The motions of the lower jaw were recorded by ELITE system, i.e. the measurement instrument that by stereo-photo-grametric procedures calculates space co-ordinates of markers on faces of the study subjects. The system enables continuous recording of lower jaw motions in three dimensions, without any possibility of the study subjects' influencing the operation of the instrument, which significantly decreases the possibility of error. Study results have shown that in all 19 subjects a greater food consistency increases the extent of chewing motion. In each individual study subject different average values were found for equal shifts of lower jaw when chewing the same type of food. Although varying from subject to subject, the chewing cycle depends to a great extent on food consistency. By increasing the consistency of a bite, the extent of lower jaw motion has increased in every single study subject.

Adult↗

Organizational design consistency: the PennCARE and Henry Ford Health System experiences.

There has been much discussion of the appropriateness of various organizational strategies for today's healthcare industry. This article presents case studies of two healthcare organizations that have pursued very different configurations. PennCARE uses a virtually integrated, loose contract-based arrangement, while Henry Ford Health System employs a vertically integrated, tight ownership model. Despite these different approaches, their overall designs are strikingly similar. In essence both systems demonstrate a property called organizational design consistency; they simply approach it from different ends of the spectrum. This article presents the notion of organizational design consistency and defines it as the steady pursuit of a single preferred configuration strategy across key elements of organizational design. To illustrate the framework the case studies target four key elements of organizational design (governance structure, organizational culture, strategic planning processes, and decision-making procedures) and explain how consistency across these components adds value to both of these differently configured healthcare systems. There is room enough for diverse configurations of organizations in the current healthcare environment. Consistency does not mandate conformity; value can be derived from both tight and loose models. Furthermore, when fashioning organizational design consistency strategies, healthcare systems should carefully choose tightly or loosely modeled configurations to appropriately suit their aims, their markets, and the capabilities and resources available to them.

Contract Services↗

[Controlled pathological study and preoperative MRI evaluation of the consistency of pituitary adenomas].

BACKGROUND & OBJECTIVE: Consistency of pituitary adenoma may influence surgical remote of the tumor. Preoperative evaluation of tumor consistency will be useful in guiding the operative approach. This study was designed to investigate the relationship among pituitary adenoma consistency, collagen type I and MRI signal intensity. METHODS: Twenty pituitary adenoma patients received transsphenoidal surgery. Preoperative MRI, H-E stains and collagen type I immunohistochemistry(IHC)-autonomic image analysis for tumor specimens were performed RESULTS: Ten tumors were soft, mean T2WI tumor/while matter signal intensity ratio (TWSIR) is 17.38%; six were moderate, mean T2WI TWSIR was 2.01; and 4 were firm, mean T2WI TWSIR was 1.56. Mean collagen type I positive area ratio(CIPAR) of soft, moderate, and firm tumors was 17.38%, 27.30%, and 40.31%, respectively. Both C1PAR and T2WI TWSIR were significantly different among three types (P < 0.01) C1PAR was negatively correlated to T2WI TWSIR(P < 0.01). CONCLUSION: Collagen type I content relates with the consistency of pituitary adenomas. MRI can predict of pituitary consistency adenoma; and those show hypointensity in T2WI are firm.

Adenoma↗

Consistency testing of diphtheria and tetanus to replace potency testing for lot release.

Diphtheria and tetanus vaccines are among the most effective and safe vaccines in the EPI programme. Their mechanism of toxicity and clinical protection is well documented and toxin neutralising antibodies induced by the vaccines are generally accepted as correlates of protection. Despite these positive aspects there are still no generally accepted methods to estimate their potency for routine lot release. Some of these tests use large numbers of animals and rely on lethal challenge tests. Consequently there are ethical and financial barriers to perform these tests. Test results expressed in IU, depend on the animal species or strain used and there is limited information about their predictive value for clinical protection. WHO, supported by the ECBS, has made a proposal to harmonise the current methods into simplified consistency tests, after clinical safety and efficacy, as well as consistency in manufacturing has been established to the satisfaction of the National Regulatory Authority. In principle these tests aim for a proof of consistency in biochemical and immunological characteristics in comparison with the lots shown to be clinically safe and effective. Given that many manufacturers have recently made, or are planning to make clinical trials with new combination vaccines in the near future, recent clinical data are already available, or will be soon, on the clinical safety and efficacy of the D and T components present in these combination vaccines. This will create a unique opportunity to compare the biochemical and immunological characteristics of routinely produced vaccine lots with the clinical lots and to use the consistency approach as suggested by WHO for lot release purpose. Background information and an update will be given about the proposed consistency approach of WHO for routine lot release of the D and T components in vaccines.

Animals↗

[Studies on synthesis of polyhydroxyalkanoate consisting of 3-hydroxyvalerate by Aeromonas hydrophila].

Polyhydroxyalkanoates (PHA) is a family of microbially synthesized polyesters consisting of various 3-hydroxyalkanoate monomers. Aeromonas hydrophila 4AK4 could be able to synthesize PHA copolymer consisting of 3-hydroxybutyrate (3-HB) and 3-hydroxyhexanoate (3-HHx). No data has been reported about the ability to synthesize the PHA with other monomers in A. hydrophila. In this study, propionic acid, valeric acid, heptanoic acid, nonanoic acid and undecanoic acid were used together with gluconate to find out whether A. hydrophila 4AK4 could synthesize the PHA consisting of odd carbon atom number monomers. The result showed that A. hydrophila 4AK4 could not growth when supplied with propionic acid, valeric acid, heptanoic acid and nonanoic acid and only undecanoic acid could be used to synthesize PHA. Wild type and recombinant A. hydrophila 4AK4 harboring phaA (beta-ketothiolase) and phaB (acetoacetyl-CoA reductase) were cultivated with undecanoic acid and glucose or undecanoic acid and gluconate served as carbon sources. PHA consisting of 3-HB and 3-hydroxyvalerate (3-HV) could be produced by both wild type and recombinant A. hydrophila 4AK4 and the latter could produce PHA with more 3-HB monomer. When the ratio of glucose or gluconate to undecanoic acid was 1:1, the cell dry weight (CDW) of A. hydrophila 4AK4 reached 1.14 g/L and PHA content was 60% of the CDW after cultivation for 24 h. When lauric acid and undecanoic acid were served as co-substrate, A. hydrophila 4AK4 could produce copolyester consisting of 3-HB, 3-HV and 3-HHx. Along with the increase of undecanoic acid proportion in the mixed carbon source, the 3-HV content of copolymer was increased while the 3-HB and 3-HHx content were decreased. In all cases, the CDW decreased along with the increase of undecanoic acid concentration, which indicated that undecanoic acid was not very good for A. hydrophila 4AK4 growth.

Aeromonas hydrophila↗

Consistency of condom use for disease prevention among adolescent users of oral contraceptives.

A six-month prospective study examined consistency of condom use for disease prevention among 308 adolescent women who had received a prescription for oral contraceptives at a family planning clinic. Only 16 percent used condoms consistently over a six-month period, yet 30 percent were considered at high risk for sexually transmitted diseases (STDs) because of multiple, sequential or concurrent relationships with male partners. The type of relationship in which the adolescents were involved did not predict consistency of condom use. Consistent condom use was associated with having asked a partner to use a condom, perceiving partner support for condom use, having less frequent sexual intercourse and using oral contraceptives inconsistently. The findings suggest that family planning providers need to more strongly emphasize to adolescents the importance of consistent condom use to protect against STD infection.

Adolescent↗

Significance of intraoperative measurement of liver consistency prior to hepatic resection.

The functional reserve of the liver should be estimated prior to hepatectomy. While the experienced liver surgeon often relies on the findings of manual palpation intra-operatively, this approach remains a subjective one. In 22 of our patients scheduled for hepatectomy, we measured intra-operatively hepatic consistency as well as the parameters of liver function. Hepatic consistency is augmented during progression from non-fibrosis to cirrhosis. We found a statistically significant correlation between liver consistency and the indocyanine green retention rate at 15 minutes (r = 0.682; p = 0.0009) and portal vein pressure (r = 0.733; p = 0.0008). Prothrombin time, the hepaplastin test, total bilirubin and glutamic pyruvic transaminase showed no significant correlation with hepatic consistency. The safety limits of the hepatic blood circulation for the performance of hepatectomy can be estimated using parameters of consistency in this organ.

Carcinoma, Hepatocellular↗

Automated medical knowledge acquisition: a study of consistency.

Knowledge bases are more representative of the population of medical experts if they are constructed by a group of individuals, rather than one practitioner. However, one runs into problems with consistency when information is elicited from a group without a consistent format and terminology. This study examines the consistency of relatively unconstrained computer-elicited medical knowledge using the computer program, KSSO. The results of this study show that the group of ten general internists were somewhat consistent in the diagnoses they listed for a patient presenting with chest pain. They were much less consistent in the findings they listed to differentiate between the diagnoses they had listed. The mean number of subjects listing each diagnosis was 3.3 +/- 2.7 while the mean for findings was 2.0 +/- 1.5. The implications of these data are discussed.

Artificial Intelligence↗

Variability and consistency of electric and magnetic field occupational exposure measurements.

There is widespread scientific and public interest in possible health effects from exposure to electric and magnetic fields at frequencies associated with electricity use. Electric and magnetic field exposure assessment presents specific problems, among which are the inherent variability in exposure, the lack of robust statistical summary measures, and the lack of an accepted metric based on biological response. These pose challenges in defining distinct exposure groups, a basic goal for exposure assessments used in epidemiological studies. This paper explores the extent to which distinct electric and magnetic field exposure groups can be defined, by examining the variability and consistency of occupational electric and magnetic field exposure measurements among studies and within individual studies. Principal analyses are made by job titles because they are the most frequently used descriptors for stratifying occupational exposures to electric and magnetic fields. Methodological issues affecting the degree of consistency in measured electric and magnetic field exposures among occupational environments are also examined. Exposures by job title reported from electric and magnetic field measurement studies are summarized by general job category and industry. Analyses are performed both within and between job categories. Distributions of daily measured exposures for job categories taken from three large studies in the U.S. electric utility industry are compared to investigate consistency of exposures at a more detailed level. Analyses of reported personal exposure measurements from many studies and countries are consistent with less rigorous observations made heretofore on the basis of individual studies. In these studies, significantly elevated electric and magnetic field exposures are found in the electrician, lineworker, and substation worker categories; significantly elevated magnetic field exposures are also noted in the generation worker category; and magnetic field exposures in these groups are consistent across countries. Analyses within and among the elevated exposure job categories indicate that there are no significant differences between them. Among the studies, it is not possible to distinguish between exposures for well-defined groups within the categories, such as between transmission lineworkers and distribution lineworkers in the lineworker category; between generation operators and generation mechanics; or between substation operators and substation maintenance workers. This information provides a context for past studies and will help future efforts to define distinct occupational exposure groups exposed to electric and magnetic fields. Compilations of measured personal exposure data by industry and job title have been prepared as appendices (available from the author upon request).

Analysis of Variance↗

[Internal consistency, factorial validity and discriminant validity of the French version of the psychological demands and decision latitude scales of the Karasek "Job Content Questionnaire"].

BACKGROUND: The job demands-control model developed by Karasek has greatly influenced research on psychosocial factors at work and health. Validity of the English version of the psychological demands and decision latitude scales is documented. Psychometric qualities of the French version are investigated here in a representative sample of the general population, including blue-collars and white-collars. METHODS: The French translation of the psychological demand and decision latitude scales was administered by interview in a representative sample of the Quebec working population (N = 1,110). Internal consistency and factorial validity of the instrument were studied among white-collars and blue-collars separately. Discriminant validity was assessed for the whole population. RESULTS: Cronbach alpha coefficients, varying between 0.68 and 0.85, support the internal consistency of the scales. Demographic distribution of the scales and intercorrelations were consistent with the English version. Results of the factor analysis were consistent with the two dimensions expected from the theory. Mean scale scores and variations in the prevalence of high psychological demands combined with low decision latitude by age, sex, education, and job category support the discriminant validity of the instrument. CONCLUSIONS: Results support internal consistency, factorial validity, and discriminant validity of the French version of the psychological demands and decision latitude scales of the Karasek "Job Content Questionnaire" for white-collars and for blue-collars of the general population.

Adolescent↗

Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index.

For breast cancer, many prognostic markers that initially appeared promising have failed to maintain their clinical predictive value. Few reports have analyzed the consistency over time of biological and clinical information provided by biomarkers. Tumour cell proliferation has acquired relevance as an indicator of prognosis and of response to treatment. Since its clinical role has been investigated for some decades, cell proliferation represents an ideal marker for an over-time validation. In 3,800 node-negative breast cancers recruited between 1972 and 1991, the consistency of information provided by the 3H-thymidine labelling index (TLI), in terms of basic relations with other clinico-pathological and biological variables and clinical predictivity, was evaluated using a combined analysis of results previously published by our group for distinct series of patients. Clinical predictivity was analyzed on a subset of 2,067 patients given local-regional therapy until relapse and followed for a median time from 6 to 10 years. Over the entire period TLI maintained a weak direct relation with tumour size and an inverse strong relation with steroid receptors. An increase in TLI was observed for tumours in post-menopausal patients up to the mid 1980s. During 3 different accrual periods (1972-1983; 1984-1987; 1988-1991), TLI was a consistent and independent predictor of relapse-free time, distant metastasis and overall survival, regardless of its consideration as a continuous variable or with a cutoff value of 3%. The reproducibility of our results over time provides support to the consistency of the methodology used and of the biological and clinical information obtained when using TLI as an indicator of breast cancer cell proliferation.

Adult↗