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At least 181 records · Page 10Linked to original sources

Gallstone expectoration following laparoscopic cholecystectomy.

Laparoscopic cholecystectomy is the treatment of choice for uncomplicated gallstone disease. Laparoscopic cholecystectomy may result in lost (spilled) gallstones. Such stones may precipitate various infective intra-abdominal complications. An unusual case of spilled gallstones eroding the diaphragm and eventually being expectorated out 12 months after laparoscopic cholecystectomy is reported.

Aged↗

[Combined diagnostic techniques and contemporary methods of treatment of external biliary fistula].

Analysis of surgical treatment results of 103 patients with the extrahepatic biliary ducts external fistula was presented. The external biliary fistula had formatted due to iatrogenic damage of biliary ducts during performance of cholecystectomy, gastric resection and echinococcectomy. Preoperatively correction of water-electrolytic balance disorders was done in all patients, as well as treatment and prophylaxis of hepatorenal insufficiency, anaerobic anti-infection measures. In all patients the reconstructive intervention was performed. Postoperative complications had occurred in 14 (13.6%) patients, mortality was 3.6%. The main cause of mortality is the sutures of anastomosis insufficiency, intoxication, hepatorenal insufficiency due to occurrence of purulent cholangitis and cholangiogenic abscess of liver.

Biliary Fistula↗

[A case of serous cystadenoma of the pancreas communicating with the pancreatic duct].

Serous cystadenoma of the pancreas is a rare disease and is usually benign. Mucinous cystadenoma, another cystic neoplasm of the pancreas, has a malignant potential. Serous cystadenoma is usually composed of many small cysts lined by small, cuboidal or flattened cells containing abundant glycogen. With the finding of endoscopic retrograde pancreatography, a communication between the cyst and pancreatic duct is observed occasionally in the mucinous cystadenoma, but rarely in the case of serous cystadenoma of the pancreas. We experienced a case of serous cystadenoma of the pancreas that had a communication between a cyst and the pancreatic duct.

Adult↗

Diaphragmatic defect with peritoneopericardial communication.

An 81-year-old man had a congenital defect of the central tendon of the diaphragm, including a peritoneopericardial communication with herniation of the omentum to the pericardial sac in front of the heart. In addition, he had a critically stenosed congenital bicuspid aortic valve and severe coronary artery disease. The patient underwent reduction of the herniated omentum into the abdominal cavity, coronary artery bypass grafting, aortic valve replacement, and closure of the peritoneopericardial communication with a synthetic patch. Three years later, the patient was doing well, with a normally functioning pericardial valve in the aortic position and no sign of omentum around the heart.

Aged↗

Tacrolimus for Crohn's disease.

(1) Tacrolimus (FK-506) is an immunosuppressant that is being investigated for use in patients with Crohn's disease, mainly in those with refractory illness and fistulizing patterns of the disease. (2) Evidence from a small, randomized controlled trial indicates that, compared with placebo, tacrolimus is associated with higher rates of improvement and similar rates of remission in those with fistulizing patterns of disease. (3) Nephrotoxicity, which has been reported with the use of tacrolimus in clinical trials, seems to improve with dose reduction, but may be associated with irreversible histologic changes. (4) More studies are needed to determine the optimal dose and duration of therapy, and whether the drug is beneficial to patients with non-fistulizing patterns of Crohn's disease.

Canada↗

[Endoscopic management of postoperative biliary fistulas].

Biliary fistulas have been managed by surgical correction with no good results. From 1986 to 1990, endoscopic therapy was attempted in 24 patients with postoperative persistent biliary-cutaneous fistulas. Endoscopic retrograde cholangiography demonstrated residual biliary stones in 19 patients (79%). The mean fistula drainage was 540 ml/day, and in 75% the site of the fistula was near the cistic duct stump. Sphincterotomy with or without biliary stent placement resulted in rapid resolution of the fistula in 23 patients (95.8%). In those patients treated with biliary stents the fistula healed spectacularly in 24-72 hrs.

Adolescent↗

Effects of serotonin on canine bile formation.

Long-term studies were performed on dogs previously prepared by cholecystectomy, ligation of the lesser pancreatic duct, and insertion of a duodenal cannula. After an overnight fast, bile duct cannulation and stabilization of bile flow with intravenous (IV) sodium taurocholate, serotonin, 10 micrograms/kg/min, or 0.15 N NaCl was infused. In similar experiments, animals were fed a standard meal, and serotonin or 0.15 N NaCl was infused IV beginning simultaneously with or 30 minutes after the meal. Short-term experiments were performed on dogs anesthetized with pentobarbital and prepared by abdominal evisceration, cholecystectomy, and bile duct cannulation. Serotonin caused significant inhibition of fasting bile formation (3.8 +/- 0.3 ml/15 min to 3.2 +/- 0.3 ml/15 min), meal-stimulated choleresis (4.0 +/- 0.3 ml/15 min to 3.5 +/- 0.3 ml/15 min), and bile flow in eviscerated animals (1.6 +/- 0.1 ml/15 min to 1.1 +/- 0.2 ml/15 min). Bile acid output and 14C erythritol clearance were stable while bile bicarbonate output was decreased during serotonin infusion. A similar inhibitory effect was demonstrated with serotonin, 5 micrograms/kg/min, but the inhibition was not statistically significant with 2.5 micrograms/kg/min. These studies demonstrate that serotonin inhibits bile acid-independent bile formation, possibly at the ductular level, and the inhibition occurs independently of endogenous gastrointestinal tract hormone secretion.

Animals↗