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Finnish stakeholder engagement in the restoration of a radioactively contaminated food supply chain.

An expert group was established in 2001 representing various organisations and authorities responsible for primary production, food processing, the distribution and consumption of foodstuffs, food safety and availability, catering and extension services, nature conservation, research into environmental impacts, and the media. The aim was to strengthen networking and improve the stakeholder response to accidental radioactive contamination of rural areas through participation in the FARMING network project. A hypothetical contamination of a large milk-producing area provided a suitable framework for evaluation of actions ensuring clean feeding of dairy cows during grazing. The following year the group received a compilation of rural countermeasures and waste disposal methods, described by the STRATEGY project. The robust, uncomplicated approach of the evaluation meetings was fruitful and efficient, and the multidisciplinary group was capable of taking shared views on various measures after updating their knowledge together. High priority was given to measurements of radioactivity and the provision of information and advice to a wider audience.

Agriculture↗

Nitrite poisoning caused by food contaminated with cooling fluid.

Two fatal cases of nitrite poisoning are described. From the identical clinical picture of both patients (fulminant fall of blood pressure, remarkable cyanosis attributed to methemoglobinemia, and "nasi" vomit), food poisoning seemed to be the most likely cause. Laboratory findings revealed that the food had been contaminated during transportation in a van by a leaking cooling fluid which contained sodium nitrite as anticorrosive agent.

Adult↗

Disease outbreak in laying hens arising from the consumption of fumonisin-contaminated food.

1. During the last quarter of 1995 an unusual disease outbreak characterised by black sticky diarrhoea, severe reduction in food intake, egg production and body weight follow by lameness and death was observed in 2 layer farms in Andhra Pradesh. A total of 6700 hens of 64 weeks age and 3000 hens of 36 weeks age were affected. 2. Around 10% mortality and a 20% reduction in egg production was observed. Postmortem examinations showed pale yellow coloured livers with peripheral congestion, mild haemorrhage in the proventriculus and watery accumulations in the intestine. 3. The disease was traced to a new batch of food and its withdrawal improved the health status of the flocks. 4. Analysis of the diet indicated contamination with fumonisin B1 up to 8.5 mg/kg and aflatoxin B1 up to 0.1 mg/kg. 5. Diarrhoea was induced in day old cockerels by feeding the suspect diet containing 8.5 mg/kg fumonisin B1, and in laying hens by feeding a normal diet with fumonisin B1 additions of 8 and 16 mg/kg.

Animal Feed↗

[Food contamination by PCBs/dioxins in Belgium: analysis of an accident with improbable health consequences].

In 1999, a food crisis broke out in Belgium as a result of the accidental contamination of animal feed by PCBs (polychlorobiphenyls) and dioxins (mainly furans). The analysis of the database from the PCB food monitoring program implemented after the discovery of incident confirms that the contamination has been very limited, both in time (peak at the end of January) and in the food chain (affecting less than 0.5% of the farms in the whole country). The extreme scenario of a doubling of the PCB and dioxin body burden as envisaged in "Nature" (401: 231-232, 1999) could have been conceivable only in the case of farmers who would have consumed their own products. But even in such an extreme case, this would mean going back to the levels of PCB and dioxin body burden of subjects living in the 1980s or of those regularly eating contaminated seafood.

Accidents↗

[Injury to the immune system by food contaminated by environmental toxins].

Immunity may be used as bioindicator for environmental toxic substances: Low level concentration of Pb, Cd, nitrosamines, Benzopyrene, nicotine and saturated fatty acids in food lead after application over months to a reduction of cellular and humoral immune response. After challenge by different infectious agents mortality was higher in the experimental group of mice. Up to date, investigations with low level doses of toxic agents in food running over a longer time had not been performed.

Animals↗

Tamoxifen prevents induction of hepatic neoplasia by zeranol, an estrogenic food contaminant.

Zeranol (alpha-zearalanol) is a beta-resorcylic acid lactone (RAL) that has estrogen activity. It is synthesized by molds and is difficult to avoid in human food products. We tested the ability of this mycoestrogen to damage the liver of the Armenian hamster, a rodent that is especially sensitive to hepatotoxic effects of exogenous estrogens. Zeranol induced acute hepatotoxicity and, subsequently, hepatic carcinogenesis; both effects were blocked by tamoxifen, suggesting estrogen receptor mediation. Because zeranol is acting alone as a primary initiator of hepatic neoplasms, this model provides an unusual opportunity to study the pathogenesis of estrogen-initiated tumorigenesis.

Animals↗