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Biological control of insect pests is characterised by a persistent, strong reduction in the pest population following the introduction of a natural enemy. Analysis of mathematical models suggests that differential exploitation of patches of the pest in a spatially heterogeneous environment provides the most likely mechanism to account for known successes.
Recent advances in insect genetic engineering have opened up new possibilities in the genetic control of insect vectors of human diseases. We outline the current state of the sterile insect technique and show how the use of engineered dominant lethals can greatly increase the effectiveness of this approach. We consider alternative strategies based on the use of conditional dominant lethals that are not always active in the environment.
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Eleven of 180 local isolates, belonging to Bacillus thuringiensis, were tested for their pathogenicity to pinkbollworm larvae (Pectinophora gossypiella). Three strains, namely RS-25, RS-35, and RS-45, showed a positive insecticidal activity. Their activities based on the crystalline inclusion bodies. The LD50 (hours) for larvae was 8, 12, and 6 hours, respectively.
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