Iron deficiency and infant development.
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Neurologic and developmental performance during the first year of life was correlated with maximum neonatal serum bilirubin levels for 27,000 infants in the Collaborative Perinatal Project. The infants were grouped by race and by five birth weight/gestational age categories to control for the effect of these factors on hyperbilirubinemia and developmental outcome. Low mean eight-month motor scores and delayed one-year motor development were associated with serum bilirubin levels in the range of 10 to 14 mg/dl and above. This relationship was strongest for low-birth-weight/short-gestational-period infants. A persistent association of developmental outcome with hyperbilirubinemia was found over and above the variation of maturity within the birth weight/gestational age categories.
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Infants generally begin to recognize emotional expressions after 6 months of age; some reports have even observed recognition in neonates. Emotional recognition is important for social referencing, in which infants "read" their parents' expressions to understand events. Three methods for studying how infants come to recognize emotion are described in this article: peek-a-boo, matching faces and voices, and multimodal presentation.
Repeated nutritional assessments were made on 118 low-income women who registered at an urban hospital clinic prior to the twenty-eighth week of pregnancy and then on 122 comparable women who were provided with protein-mineral supplementation. Demographic and background information were obtained. Medical assessments were carried out throughout pregnancy, labor, delivery, and the postpartum period. The infants were assessed both medically and with Brazelton Neonatal Behavioral Assessment Scales. In spite of their low-income status, the subjects did not appear nutritionally deprived. Few significant relationships were obtained between maternal nutritional intake and measures of maternal or infant medical status or infant psychological status. A limited number of consistent relationships were obtained when the supplemented and nonsupplemented groups were compared. Although consistent infant medical and psychological benefits were not noted, mothers in the supplemented group developed fewer parameters of pre-eclampsia and had fewer complications during labor and delivery.
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The role of iron in the child organism, as well as the blood's role in regulating the iron homeostasis is described on the basis of relevant literature. From developmental data on Warsaw children and from relevant literature, the child average body iron content and the child average daily iron requirement, which is at age 0-0.5, 0.5-1 and 1-2 years 0.51, 0.92 and 0.76 mg for boys and for girls 0.42, 0.86 and 0.74 mg respectively, are calculated. It is noted that the daily physiological iron loss during the first two years of life can be as much as 50% of the daily iron requirement. Among the causes of infant iron deficiency are the greater blood losses during the peri- and postnatal periods, decreased dietary iron, as well as increased need for iron related to significant body growth. The loss of one ml of blood in children results in the loss of from 0.33 to 0.66 mg of iron. On the basis of the changes in body iron content of infants having various birth weights, it is shown that the quantity of iron needed for proper development is independent of the birth weight. The quantity of iron required by premature infants and children with low birth weight is 25-50% greater, after the infant doubles its birth weight, than that needed by full-term and normal birth weight infants.
A total of 124 mothers from three cultural groups living in the same British city were asked to give the ages at which they expected their one-month-old infants to achieve three motor milestones. Jamaican mothers expected their infants to sit and walk much earlier than their English and Indian counterparts. The Indian mothers gave later estimates for crawling than those of the other two groups. The actual ages at which the abilities were attained closely reflected the cultural differences in expectations between the Jamaican and English mothers. Jamaican mothers were particularly accurate in predicting sitting age. These results are discussed in relation to cultural theories of child development, together with their implications for child health in multicultural societies.
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A developmental questionnaire, encompassing the ages from 4 weeks to 36 months, has been devised that, when completed by parents, can be used to screen children as being developmentally normal, questionable, or abnormal. A total of 526 infants were screened by this questionnaire at 28 weeks of age and then examined at 40 weeks of age by a full Gesell Developmental and Neurologic Examination. Underscreening of those with major abnormalities was 2.6%, and of those with minor abnormalities, 10%. Overscreening was 6%. In view of the demonstrated high reliability and validity of the full Gesell Developmental and Neurologic Examination on which the questionnaire is based, the relatively small percentages of overscreening and underscreening make it the most accurate and useful screening questionnaire to date.
The course of severe depressive symptoms from pregnancy to 6 months postpartum, as well as the occurrence of severe paranoid symptoms prenatally, were examined by the Millon Clinical Multiaxial Inventory I and the Beck Depression Inventory, in 78 women who were heavy, chronic cocaine users and who retained custody of their children after birth. Six months postpartum, the quality of caregiving was observed and assessed in the home, and the children were assessed on the Bayley MDI Index in the laboratory. Mothers who were depressed and paranoid prenatally, regardless of whether the depression continued to 6 months postpartum, were less sensitive in caregiving than women without severe symptoms of paranoia or depression during pregnancy or those who reported only depression that lifted by 6 months postpartum. Mothers who were depressed prenatally and continued to be depressed by 6 months postpartum, regardless of the presence or absence of paranoia, had infants who earned lower Bayley MDI scores than the offspring of women without severe psychological symptoms or women whose depression had lifted. Severe depressive symptoms during pregnancy, if they did not continue to 6 months postpartum, did not appear to adversely influence either caregiving or infant functioning.
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