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Inflammatory linear verrucous epidermal nevus in patients with positive results of tests for human immunodeficiency virus 1.

Inflammatory linear verrucous epidermal nevi are rare lesions that have many similarities to psoriasis on histologic examination, and are resistant to therapy. The two lesions reported occurred in patients with positive results of tests for human immunodeficiency virus 1 and showed features consistent with psoriasis. Results of tests for immunohistochemical markers were also consistent with previous findings and expected staining patterns in lesions of psoriasis. Our findings suggest that inflammatory linear verrucous epidermal nevi represent a clonal dysregulation in growth, probably secondary to an inflammatory stimulus. Since human immunodeficiency virus 1 has been associated with onset and exacerbation of psoriasis, perhaps this virus or another secondary infection associated with human immunodeficiency virus 1 infection could also play a role in the onset of this rare lesion.

Adult↗

[Chromomycosis: 2 cases].

We report two cases of chromomycosis due to Fonsecaea pedrosoi and Cladosporium herbarum, observed in two women from the Tlemcen region. Due to the wart-like or nodular lesions, these case were mistaken for other skin diseases with similar manifestations, particularly verrucous tuberculosis and cutaneous leishmaniasis. The histology revealed fumagoid bodies leading to the identification of the causative agents. Chromomycosis is rare in Algeria although 3 cases have been observed in our area since 1989. The physician should be aware of this diagnosis.

Aged↗

[Location of single skin lesions of paucibacillary leprosy].

In this paper the authors study the sites of single lesions in 317 paucibacillary patients registered at the outpatient units of the CMS Jorge Saldanha and the Curupaiti State Hospital in Rio de Janeiro, Brazil. The preferential sites of lesions in the population studied, their relation with age and sex and factors likely to influence their distribution are discussed. The findings are compared with other similar studies performed in Asia and Africa.

Adolescent↗

Phytophotodermatitis: a visit to Margaritaville.

Phytophotodermatitis is a phototoxic eruption following contact with photosensitizing compounds and long-wave ultraviolet light. The most common phototoxic compounds are the furocoumarins contained in a wide variety of plants, especially of the Umbelliferae, Rutaceae, and Moracea families. Commonly occurring photosensitizing plants include citrus fruits such as limes and oranges and many vegetables, notably celery, parsnip, parsley, carrots, and dill.

Adult↗

Lichen simplex chronicus.

A review of the literature for the last 20 years shows no monumental advances in the diagnosis or treatment of the disease; however, there have been some very intriguing insights into the causes. The physical and emotional aspect of the skin condition is well known but the genetic, vascular, and neurogenic implications are of interest.

Diagnosis, Differential↗

[Perforating necrobiosis lipoidica: 2 cases].

INTRODUCTION: Perforating necrobiosis lipoidica is a rare clinical form of necrobiosis lipoidica and is almost always associated with diabetes. Necrotized tissue is usually eliminated via transfollicular perforations. CASE REPORT: We report two cases of perforating necrobiosis lipoidica associated with type II diabetes mellitus. The characteristic clinical feature was the presence of keratotic plugs around the periphery of the lesions. Transfollicular perforation predominated in the first case. The second also presented epidermal perforation. DISCUSSION: There have been only 6 cases of perforating necrobiosis lipoidica in the literature. To our knowledge, this is the first case report of transepidermal elimination. We confirmed the constant association between this perforation type and diabetes mellitus.

Diabetes Mellitus↗

[Acute necrotizing cutaneous streptococcal infection following bites or scratch by dog or cat].

INTRODUCTION: Domestic animal bites or scratches are quite frequent. Among banal bacteria isolated from infected bites or scratches, group A streptococcus seems to be frequently associated with severe infections. CASE REPORTS: Three cases of acute necrotizing cutaneous streptococcal infections, following cat or dog bite or scratch are reported. Twice, group A streptococcus was isolated from cutaneous swabs. In the third case, previous antibiotic therapy had sterilised bacteriological samples. Diagnosis was ascertained on the basis of clinical presentation and significant antistreptococcal antibodies elevation. Skin necrosis around the inoculation area was observed in the 3 cases. Cicatrisation required an average of two months under appropriate treatment. DISCUSSION: An evolution towards cutaneous necrosis localized to the initially injured area is common to these three cases. This peculiar evolution is worth to be known in order to choose an effective anti streptococcal antibiotherapy whenever domestic animals bites and scratches are to be treated.

Acute Disease↗

Purpuric lichen nitidus.

We report the case of a patient in whom lichen nitidus with hemorrhage was found on the palm and the thigh. Histopathologically, the small vessels in the lesions showed extensive changes and were increased in number. The capillary walls revealed degenerative changes with extravasation of erythrocytes. On electron microscopy, amorphous, electron-dense deposits were observed along the outside of the endothelial cells. These findings can explain the presence of the hemorrhagic changes. We describe this as a case of purpuric lichen nitidus.

Hand Dermatoses↗