DEMODEX CANIS IN CANINE TISSUES.
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Cutaneous manifestations of bird and rat mite infestation in man are not easily recognized by physicians or patients. Clinical signs and symptoms are developed secondary to bites of mites that have infested rats, domestic poultry or birds nesting in or near human habitation and comes into contact with man. This study details 4 cases of pruritic dermatitis developed in four field workers in poultry farms in Al-Marg district, Qalyobia governorate, Egypt. The zoonotic species of Ornithoyssus sp., (Family Macronyssidae) was isolated from all samples collected from patients' habitat and the role played by Ornithonyssus mites in causing dermatitis in man was discussed.
Worker honey bees from genetic strains selected for being resistant (R) or susceptible (S) to tracheal mites typically show large differences in infestation in field colonies and in bioassays that involve controlled exposure to infested bees. We used bioassays exposing newly emerged individuals to infested workers to compare the propensity for tracheal mites to infest queens, drones and workers from R and S colonies. In tests with queens, newly emerged R and S queens were either simultaneously confined in infested colonies (n = 95 and 87 respectively), or individually caged with groups of 5-20 infested workers (n = 119 and 115 respectively). Mite prevalence (percentage of individuals infested) and abundance (foundress mites per individual) after 4-6 days did not differ between R and S queens. In another test, five newly emerged drones and workers from both an R and an S colony, and a queen of one of the two strains, were caged in each of 38 cages with 20 g of workers infested at 60-96% prevalence. Infestations of the R queens (n = 17) and S queens (n = 19) did not differ significantly, but R workers had half the mite abundance of S workers, while R drones received about a third more migrating mites than S drones. In tests to evaluate possible mechanisms, removal of one mesothoracic leg from R and S workers resulted in 2- to 10-fold increase in mite abundance on the treated side, but excising legs did not affect infestation of the corresponding tracheae in drones. This suggests that differences in infestation between R and S workers, but not drones, are largely determined by their ability to remove mites through autogrooming. If autogrooming is the primary mechanism of colony resistance to tracheal mites, selection for resistance to tracheal mites using infestation of hemizygous drones may be inefficient.
Immunocytochemistry was used to identify possible target antigens in the digestive system of Psoroptes cuniculi. Sera from three recently acutely infested rabbits, from rabbits with a mild long lasting infestation, and from a rabbit with repeated mite infestations and no longer able to maintain a population of P. cuniculi were used to determine any antibody specificity to the mite digestive system. The reactivity of these sera was compared with sera from three un-infested animals. The different pool of sera targeted different mite antigens; in particular, sera from the resistant rabbit and the chronically infested rabbits reacted with gut cells, faecal material and cuticle, while sera from the recently infested rabbits reacted with gut contents, faecal material and cuticle of the parasites but not with gut cells. Finally, sera from un-infested rabbits did not demonstrate any specificity to P. cuniculi antigens reacting only with mite gut contents in a weak manner. These preliminary data suggest the presence of antibodies induced in the host blood by infection, which act against the parasite by binding to antigen at the surface of its gut.
Laying hens were treated with permethrin at the rate of 20 mg per bird to determine efficacy against northern fowl mites Ornithonyssus sylviarum (Canestrini and Fanzago) and the dissipation of residues over a 42-day period. Permethrin provided greater than 99% control of mites for at least 42 days posttreatment as compared to malathion which did not substantially reduce mite infestations. Carbaryl and coumaphos treatment resulted in limited reductions with mite populations recovering by two to three weeks posttreatment. Maximum residues of permethrin in breast muscle, body fat and the uropidium occurred on day 1 posttreatment and were still present in fatty tissue in detectable quantities on day 42. Residues in egg yolk appeared on day 3 posttreatment and peaked on day 7 with trace quantities still present on day 21. Permethrin was not found in egg white. Low residues were found in the liver and gizzard from day 1 through to day 7.
During October-December 1987, chigger mites infested on the striped field mice (Apodemus agrarius coreae) collected at Pochun-gun, Gyeonggi Province and Chinhae city, Kyongnam Province were identified. 1. Of 171 back-striped mice collected, chigger mites were found from 58 mice, showing 33.9% of infestation rate. 2. Total 865 chigger mites collected were classified into seven species; Leptotrombidium pallidum (4.3%), L. palpale(23.0%), L. orientalis(20.2), L. zetum(19.0%). Neotrombicula tamiyai(32.9), N. japonica(0.2%) and Euschongastia koreaensis(0.3%). Though the most dominant species in number was N. tamiyai(32.9% of the total), this species was collected at very limited locality and for a short period. Therefore, most common species in Korea seems to be L. palpale which was found at all localities throughout the whole survey period. L. pallidum which is known as the vector species of tsutsugamushi disease in Korea was collected in a very low number(4.3% of the total chiggers collected). 3. The number of chigger mites infested on a host animal showed great variations from one chigger up to 207 chiggers. The present study has shown that there may be other Leptotrombidium species mite(s) for the vector and host of tsutsugamushi disease in Korea.
Avian mite infestation is a rare cause of pruritic dermatoses in humans. The mites spend the majority of their life cycle on the avian host but may be transmitted to man as a result of direct contact and also through airborne spread. We describe a case of infestation with the Northern Fowl Mite (Ornithonyssus sylviarum) from an abandoned birds nest in the roof of a patients home. This caused a pruritic erythematous papular eruption on exposed sites that settled with topical steroids. We discuss the diagnosis and range of clinical manifestations produced by avian mites.
Five goats naturally infested with Sarcoptes scabiei, Psoroptes ovis and Bovicola caprae were treated with a combination of ivermectin and clorsulon. A subcutaneous injection in a dose of 1 ml/50 kg live weight was given. This provides dose levels of 200 ug ivermectin and 2 mg clorsulon. Four goats were cured from the three ectoparasites within one to two weeks. The last elder goat, which was anaemic and naturally infected with Trichostrongylus colubriformis, was still infested with the two scab mites, but was free from B. caprae. A postal dose of 0.5 ml/50 kg live weight was given one week later (=3 weeks after the 1st injection). This goat was cured within a week, but still passed some T. colibriformis eggs. The result was discussed.
Anaphylaxis after eating mite-infested wheat flour has been recently reported. This paper is to describe two cases and examine the occurrence of mite contamination in wheat flour in Japan. Packages of wheat flour from retail outlets and homes were examined microscopically for the presence of mites. Three of 176 packages from retail outlets and seven of 127 from homes were infested with mites, and it seems likely that the mite contamination takes place in most cases at homes after the packages have been opened. No mites were found in packages stored in a refrigerator, therefore, mite-sensitive patients must be advised to store wheat flour products in a refrigerator.
BACKGROUND AND PURPOSE: Ivermectin is a common anthelmintic drug, widely used in laboratory rodents for treatment of pinworm and mite infestations. We evaluated the action of ivermectin on sensitive behavioral tasks in mice during treatment for mites within a barrier facility. METHODS: A total of 21 (5 males, 16 females) mice (129/SvEv) were used for measuring body weight, open field locomotor activity, and rotarod motor coordination. For acoustic startle and prepulse inhibition, 20 C57BL/6J and 29 AKR/J mice were studied. For the Morris water task, the same 20 C57BL/6J mice were studied. Ivermectin (0.08% sheep drench) was administered in the drinking water of the home cage for 8 weeks. Control groups received normal tap water in identical bottles. RESULTS: Ivermectin did not affect general health, body weight, motor coordination, swimming behavior, or spatial learning in several inbred strains of mice. However, it induced a small but significant effect on some sensitive behaviors. CONCLUSIONS: A cautious approach to initiating ivermectin treatment in mice should be used for sensitive behavioral experiments.
We studied the effect of a recently-developed special mite-preventive futon (bedding) on mite population and mite allergen contents (Der I and Der II) in asthmatic children and their families (23 sets) for 2 years. 1. The number of mites (vacuumed samples) in the 124 sets of futon for 2 years was 6.4 (SD +/- 8.8) in average in the mite-preventive futon which was significantly smaller than the number (about 1/10) in the control futon: 70.0 (SD +/- 99) (p less than 0.001). 2. Follow-up studies were made on the mite population about 2 years (3, 6, 9 12 and 27 months afterwards). The numbers of mites in all the mite-preventive futon was always 1/10 or less than that of in the control futon (p less than 0.01). 3. The mite allergens (Der I and Der II) were measured in the cotton stuffing of the futon used for 2 years. The mite allergen counts in the mite-preventive futon averaged about 1/24 of those in the control futon. 4. Airborne mite allergens (Der I and Der II) obtained by beating the futon were measured. The ratio of the mite allergen count in the mite-preventive futon to the control futon was found to be 1:22-264. These results indicate that the special mite-preventive futon always inhibit mite infestation at least 1/10 of that in the ordinary (control) futon and that the count of mite allergens in the cotton stuffing and in the airborne particles was even lower in the mite-preventive futon.
A randomized block design study was conducted to confirm the efficacy of topical eprinomectin against naturally acquired Chorioptes bovis mite infestations. Twelve adult Simmentaler Fleckvieh cattle were formed into six replicates of two animals based on pretreatment mite counts. Within replicates, animals were randomly allocated to untreated controls or were treated with eprinomectin 0.5% pour-on solution at 1 mL/10 kg body weight (0.5 mg eprinomectin/kg body weight). Live mites were counted, and mange lesions were scored prior to treatment and at weekly intervals until the end of the study on day 56. Feed consumption was recorded daily throughout the study, and body weights were measured. Differences between variables were declared significant if p < or = 0.05. Mite counts for the cattle treated with eprinomectin were reduced by 100% from day 14 through the end of the study (p < 0.05). At each examination from day 21 through the end of the study, treated animals were significantly clinically improved as measured by lesion scoring compared with untreated controls. Weight gain and feed conversion efficiency were numerically higher in the eprinomectin-treated group. Results of this study demonstrate a positive response in growth rate following effective treatment of cattle for chorioptic mange and underline the economic importance of the parasite and the value of treatment.