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Results for “MYXOMATOSIS, INFECTIOUS”

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PubMed1982

[Administration of vaccine against myxomatosis using live MXT by means of external ear puncture with a special needle].

A new application method was developed and tested for the immunoprophylaxis of rabbits against myxomatosis using a live MXT vaccine. This new application method--injection of the ear with a special double needle--is very simple and easy. Its use enables a five-fold increase in vaccination doses as compared with subcutaneous application while the amount of vaccine remains the same. In laboratory this method with the MXT vaccine secured a 98.2% protection of the vaccinated animals. One vaccination dose contains 18.1 to 37.2 PD50. Eleven months from a single vaccination by injecting the ear, 83% of the rabbits still remained protected against experimental infection. With the use of the new application method of injecting the ear with the special double needle, the live MXT vaccine against myxomatosis in rabbits represents an effective, easily practicable and economically advantageous direction in the immunoprophylaxis of rabbits against myxomatosis.

Animals↗
PubMed1994

[Myxomatosis in the sub-antarctic islands of Kerguelen, without vectors, thirty years after its introduction].

Myxoma virus was introduced into the Kerguelen archipelago in 1955-1956. Thirty years after its introduction, the virus is present in most areas inhabited by rabbits. Rabbit fleas and mosquitoes are absent from this group of islands and the disease is transmitted by contact. The timing of the beginning of new myxomatosis outbreaks, the absence of real epizootics as well as the higher percentage of infected males over females are specific observations in favour of this mode of transmission. The majority of 34 isolates tested between 1984 and 1988 are of intermediate virulence (Grades IIIA-IIIB). In these conditions, the impact of myxomatosis virus on rabbit populations estimated on two sites is low. Myxomatosis therefore plays only a minor role in the regulation of rabbit populations.

Animals↗
PubMed1993

[Reaction of the complement fixation test on microtitration plates: application to the serology of myxomatosis. Comparative study of the results with the reaction of indirect immunofluorescence].

The authors describe a complement fixation technique on microtitration plates, using an antigen prepared from myxomas induced in rabbits. Compared with indirect immunofluorescence this technique was less cumbersome, more economical, easier to read and (as a conventional procedure) applicable in all laboratories. Results obtained with 165 serum samples tested by both methods showed good correlation and a specificity at least equal to that of indirect immunofluorescence. Taking into account its lower sensitivity, the positive threshold value for complement fixation under the described experimental conditions was a dilution of 1:4 (H50).

Animals↗
PubMed1993

[Preliminary studies of the effect of diseases and environmental pollution on the population dynamics of wild rabbits (Oryctolagus cuniculus Linnaeus, 1758) in the federal state of North Rhine-Westphalia (Germany)].

A survey was conducted of wild rabbits (Oryctolagus cuniculus) shot in all districts of the Federal State of North Rhine-Westphalia (Germany). A total of 104 rabbits were examined during 1988 and 1989. Attempts to isolate myxoma virus and other viruses were unsuccessful. Two serum samples neutralised myxoma virus. In 1990, 210 rabbits were examined; 57 animals were subjected to tests for the presence of the virus of viral haemorrhagic disease of rabbits and 42 were tested for specific antibody. No virus was isolated. Antibody titres were judged to be significant in 5% of the rabbits tested. Bacteriological, histological and virological tests showed no evidence of ill health in these animals. With the exception of abnormal cadmium content of tissues, detailed examination of ovaries and testes and lead assays failed to reveal reduced fertility as a reason for the fall in population.

Animals↗
PubMed1977

Myxomatosis in domestic rabbits in Oregon.

An epizootic of myxomatosis involved 26 rabbitries in western Oregon. Major clinical signs were inflammation and edema of the eyelids, conjunctiva, and anogenital area. Mortality ranged from 20 to 50%. On histologic examination, intracytoplasmic inclusion bodies were readily apparent in the epithelial cells of the conjunctiva. Lymphoid depletion of the spleen was also a common finding.

Animals↗