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The double-crush phenomenon--an unusual presentation and literature review.

The double-crush syndrome was initially described by Upton and McComas in 1973. They postulated that nonsymptomatic impairment of axoplasmic flow at more than one site along a nerve might summate to cause a symptomatic neuropathy. This was suggested by their clinical observation that the majority of their patients had a median or ulnar neuropathy associated with evidence of cervicothoracic root lesions. They also hypothesized that one of the constraints on axoplasmic flow could be a metabolic neuropathy, and this is supported by the high association of diabetes and carpal tunnel syndrome. Other researchers have since reported series of patients supporting the frequent association of a proximal and distal nerve compression syndrome, including carpal tunnel syndrome associated with cervical radiculopathy, brachial plexus compression, and diabetic neuropathy. Subsequently, MacKinnon and Dellon have expanded the description of this syndrome to include a) multiple anatomic regions along a peripheral nerve, b) multiple anatomic structures across a peripheral nerve within an anatomic region, c) superimposed on a neuropathy, and d) combinations of the above. We present an unusual case of symptomatic nerve compression caused by two nonanatomic structures within an anatomic region.

Aged↗

[Decompression of individual nerves in anatomical strictures in polyneuropathies].

During clinical and electromyographical examination of one patient with diabetic and one with alcoholic polyneuropathy we found an especially severe lesion of the ulnar nerve at the elbow on one side. As the polyneuropathy generally affects the nerves symmetrically we presumed in addition some other most probably ulnar nerve compression syndrome at the elbow. Both patients were operated and the nerves were transposed (Prof. NIGST). The local finding during the operation, the improvement of the paresis of ulnar nerve and the worsening of the polyneuropathy--found simultaneously at control after 2 and 4 years--confirmed our supposition. Should in cases of polyneuropathy an especially severely damaged nerve be found, one ought to think of the possibility of an additional mechanical lesion and treat the patient accordingly.

Alcoholism↗

Neurilemmoma of deep branch of ulnar nerve presenting as ulnar tunnel syndrome.

A rare case of neurilemmoma of the deep branch of the ulnar nerve presented as ulnar nerve compression syndrome. This tumour was arising from the deep branch at the wrist just distal to the ulnar tunnel. By its proximity to the sensory division, it led to sensory symptoms in the ulnar two digits. Certain features of this case, which are uncommon are discussed.

Diagnosis, Differential↗

Compression syndromes due to hypertrophic nerve roots in hereditary motor sensory neuropathy type I.

Three patients with hereditary motor sensory neuropathy type I developed neurologic deficits attributable to hypertrophic nerve roots. Compression of the cervical spinal cord by enlarged nerve roots occurred in our index patient. Multilevel decompressive laminectomies relieved the myelopathy. An unrelated patient who had syncope precipitated by neck rotation had hypertrophied nerve roots that eroded into the transverse foramina in juxtaposition to the vertebral arteries. In a 3rd patient, compression of hypertrophied nerve roots within the thecal sac and neural foramina was associated with spinal claudication and radiculopathy, respectively.

Adult↗

[Nerve compression symptoms after a long bicycle ride--the Great Test of Strength].

Every year a bicycle-race over 540 km is arranged from Trondheim to Oslo, attracting approximately 5,000 amateur participants. It is well known that nerve compression syndromes may occur in connection with cycling, affecting in particular the ulnar nerve in the Guyon's canal and the pudendal nerve. A questionnaire study was carried out to evaluate the frequency of such complaints (N = 260). 32 (20%) of the 169 cyclists who completed the questionnaire reported numbness in the innervation area for the superficial branch of the ulnar nerve and 11% in the area of the median nerve. Approximately 15% reported paresis in the hand. The problem seemed to be transient. There was a slight tendency towards more symptoms among the most experienced cyclists, indicating that chronic compression may be more serious than the compression related to a single long tour.

Bicycling↗

Preserved cutaneous silent periods in severe entrapment neuropathies.

Noxious digital nerve stimulation during isometric contraction of hand muscles leads to transient suppression of the electromyographic activity, the so-called cutaneous silent period (CSP), which is mostly due to a spinal reflex mediated by A-delta fibers. We investigated two patients with carpal tunnel syndrome (CTS) and two patients with ulnar entrapment at the elbow (UNE), in whom routine sensory conduction studies failed to document afferent fiber continuity across the lesion site. In three patients, motor nerve conduction studies and electromyography failed to demonstrate intact efferent fibers. Noxious stimulation of digit II elicited distinct CSPs in ulnar-innervated hand muscles in both patients with CTS, and stimulation of digit V evoked CSPs in median-innervated hand muscles in both UNE patients. The presence of a CSP can only be explained by preserved A-delta fibers crossing the respective lesion site. Thus, preserved CSPs may serve to document residual nerve continuity in severe entrapment neuropathies when fast-conducting fibers are so compromised that their continuity cannot be detected by standard electrodiagnostic techniques.

Action Potentials↗

[Anatomic variants as a rare cause of distal ulnar nerve compression].

A case of anatomical variation of the course and branching of the ulnar nerve causing a nerve compression syndrome at the wrist joint is described. Decompression and transposition as well as tenotomy of the flexor carpi ulnaris were carried out, followed by improvement in neurological findings and complaints.

Adult↗

[Decompensation of a supinator syndrome in submuscular lipoma. A rare differential diagnosis of elbow pain].

Important differential diagnoses to epicondylitis humeri radialis are the nerve compression syndromes of the elbow. After a long period of conservative treatment, paresis of the motor branch of nervus radialis in this case led to the diagnosis and surgical treatment showing an unknown submuscular lipoma as the cause of a supinator syndrome with paresis of the finger extensors. In cases of therapy-resistant pain of the elbow, especially resistant to the conservative therapy of an epicondylitis humeri radialis, a nontraumatic supinator syndrome should be considered as a differential diagnosis. A tumor as the cause of a compression syndrome of the motor branch of the nervus radialis is very rare.

Decompression, Surgical↗

Vascular compression syndrome of the vestibular nerve: a critical analysis.

The rationale, indications, and surgical results of microvascular decompression for the treatment of vertigo are reviewed, and a critical analysis is made. The syndrome of disabling positional vertigo is discussed. It is concluded that (1) vascular compressive vestibular neuropathy may exist, (2) the current published diagnostic criteria for this disorder are insufficient to firmly establish the diagnosis, and (3) further work delineating this syndrome should be undertaken.

Brain↗

Diagnosis of radial nerve palsy caused by ganglion with use of different imaging techniques.

Clinical features of six cases of radial nerve compression syndrome as a result of ganglion at the elbow are reported. The usefulness of different imaging techniques for detecting the location of ganglion is compared. The posterior interosseous nerve was involved in two patients, the radial sensory nerve in one patient, and both nerves in three patients. Ultrasonography, computed tomography, and magnetic resonance imaging revealed the location of the ganglion in every patient. Ultrasonography was most convenient for screening examination when it was difficult to clearly define a ganglion by palpation. In all patients, a ganglion arose from the anterior capsule of the elbow joint. Dynamic factors in addition to compression of the nerve by ganglion may influence occurrence of the nerve palsy.

Adult↗