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PubMed1976

Four-channel radioisotope renography (complex investigations).

An attempt has been made at a fuller utilization of the information content of 131I-Hippurate in four-channel renography, recording the activities over the kidneys, heart and bladder. The four-channel system was supplemented with a digital scaler, which enabled also the volume of residual urine to be determined after renography. In functional disorder of the upper outflow tract, the examinations were performed in both supine and sitting positions. The expanded procedure has rendered the familiar method of renography more valuable and has often given essential diagnostic help when used in combination with other clinical data.

Adolescent↗
PubMed1981

[Kidney function study by radioisotope renography in lymphogranulomatosis patients subjected to radiation treatment].

An analysis of the results of renography in 68 patients with lymphogranulomatosis is presented. In 57 patients, a radionuclide investigation of renal function was carried out after irradiation of the spleen, paraaortic and iliac lymph nodes. Renograms were evaluated both qualitatively and quantitatively. The investigation established an impaired renal function in 18% of patients examined prior to radiation therapy. According to radionuclide renography, the excretory function of the tubular renal apparatus remains quite satisfactory after partial irradiation of kidneys in a dose of 38-40 Gy.

Adolescent↗
PubMed1975

The value of radioisotope renography in the followup of patients operated upon for hydronephrosis.

Isotope renography and excretory urography were perfored routinely before and 3 months after an operation on 21 patients with hydronephrosis. A year postoperatively all patients again underwent renography. Renography is a valuable and reliable method to estimate the results of an operation. By 3 months postoperatively the renograms revealed improved renal function and drainage in 75 per cent of the cases.

Follow-Up Studies↗
PubMed1975

A comparison between urography and radioisotope renography in the follow-up of surgery for hydronephrosis.

The result of surgical correction of hydronephrosis caused by chronic obstruction at the pyeloureteral junction has been evaluated clinically as well as by urography and body background substracted renography performed preoperatively and up to 65 months postoperatively. The average follow-up period was 24 months. Twenty-eight patients (29 kidneys) were operated. Clinically 24 patients were improved. Urography showed regress of hydronephrosis and/or improved urinary pelvic drainage in 22 patients, whereas kidney function is judged from renography was improved in only 8 patients. Improvement in all parameters was generally most marked during the first postoperative months. Renographic improvement was seen much more often when the contralateral (non-operated) kidney was abnormal. Thus, kidney function in terms of effective renal plasma flow is rather uninfluenced by hydronephrosis surgery if the contralateral kidney is normal, whereas clinical improvement in urinary drainage is regularly obtained. This improvement in drainage is poorly registered by renography. It is concluded that renography is an important complementary method to urography, but the method cannot replace the radiological methods in the follow-up of hydronephrosis surgery.

Adolescent↗
PubMed1999

Obstructive uropathy versus nephropathy: compartmental analysis in radioisotopic renography as a new methodology.

A study was carried out to determine the spatial-temporal distribution of the radiopharmaceutical, 99mTc-DTPA in the kidney and its compartments during renography and the use of compartmental analysis to improve the diagnostic capability of renography. A total of 60 individuals formed three groups: group A consisted of 30 normals taken as controls, group B consisted of 15 patients with unilateral nephropathy, and group C consisted of 15 patients with unilateral obstructive uropathy. This retrospective study was performed by processing of the frames acquired in the various stages of renography and determination of the time distribution of radioactivity in the aorta, the renal parenchyma and the renal pelvis. The data acquired were used to produce three curves instead of one for each kidney and to study renal function as a system of six compartments (aorta, left and right renal parenchyma, left and right renal pelvis, and bladder). In all the above compartments the differences among the three groups were significant and were quantified using the flow coefficients of the aortorenal compartments. The differences between the aortic flow coefficients (k1) were statistically significant not only between normal controls and patients, but also between individuals with parenchymatic dysfunction and patients with pelvocalyceal obstruction. The same differences were seen comparing the pelvocalyceal coefficients (k3) of all three groups. The parenchymatic coefficient (k2) presented statistically significant differences between normals and patients which were not observed between the two groups of patients (B and C). Compartmental analysis thus increases the sensitivity of renography, is objective by utilizing quantitative parameters, enables the separate analysis of the functional behavior of the various renal compartments, and improves the differential diagnosis between parenchymatic dysfunction and pelvocalyceal obstruction.

Adolescent↗
PubMedDate not supplied

[Radioisotope renography in the assessment of kidney function and urodynamics in children following the surgical treatment of hydronephrosis].

The paper provides radionuclide findings in children surgically treated for hydronephrosis. Altogether 109 children were operated on according to the technique by Andersen-Hines-Kucher with ureteral intubation and pelvic drainage. The radionuclide investigation allows determination of the time needed for functional recovery of the operated on kidney as well as visualization of changes in the contralateral follow-up period. Preoperative age-related changes in recovery of secretory and excretory functions of the operated on kidney were investigated.

Aging↗
PubMed1978

Sensitivity and specificity of radioisotope renography in renovascular hypertension.

Effective drug therapy for hypertension modifies the urgency of establishing a diagnosis of renal arterial stenosis. The cost of establishing a diagnosis must be considered with other factors in determining the usefulness of renography in renovascular hypertension. Recently published studies estimate the cost effectiveness of this procedure based on some data from a cooperative study of renal vascular hypertension. The small but costly incidence of false positives contributes significantly to the total cost of patient screening. Careful attention to technical details that are presented here could reduce false positives without sacrificing the true positives. However, even with increased specificity economic considerations would indicate limiting a screening program to younger patients or those in whom a drug regimen is unsuccessful.

False Positive Reactions↗
PubMed1986

[Radioisotope renography in the evaluation of the functional status of the kidneys in alcoholism].

Isotopic renography was used to study the characteristics of kidney function in alcoholics. A total of 178 patients with Stage I-III alcoholism and "habitual" drinkers aged 15-60 years were examined using the radiographic device "Gamma" (Hungary). Two types of pathological reaction of kidney function to chronic alcohol intoxication--acceleration and inhibition of function--are described, with accelerated function cases being predominant in the total sample. The ratio between them is determined by a stage of the disease, age and remission duration.

Adolescent↗
PubMed1980

Intravenous pyelography versus radioisotope renography combined with plain roentgenography of the urinary tract in the follow-up of patients with ureteral calculi.

Isotope renography combined with plain roentgenography of the urinary tract was compared with intravenous pyelography in the follow-up of 50 patients with pyelographically confirmed, radiopaque ureteral stone. The combined method was as informative as intravenous pyelography regarding the site of the obstruction, and gave better information on the function of the renal parenchyma and the passage of urine. Since in the combined method the level of radiation to which the patient is exposed is much lower than in intravenous pyelography, and since no allergic reaction to the combined method has been reported, it would seem useful in the follow-up of patients with roentgenographically visualized ureteral stone.

Adolescent↗
PubMed1985

Radioisotope renography in spinal cord injury.

Isotope renography was compared to excretory urography, voiding cystourethrography and endogenous creatinine clearances in 52 spinal cord injury patients. Renogram abnormalities were detected in 86 per cent of the cases. The most common abnormality was the delay of isotope excretion from the renal cortex and pelvis. Anticholinergic medication significantly reduced these excretion delays. A subgroup containing 22 newly injured patients was evaluated separately. Renogram abnormalities in this subgroup were associated with normal excretory urography and normal creatinine clearances. We postulate that the defect producing upper tract deterioration in spinal cord injury begins early, is obstructive to renal drainage, does not increase with time and probably requires early intervention with anticholinergic medication or transurethral sphincterotomy to prevent upper tract damage.

Adult↗