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At least 181 records · Page 10Linked to original sources
PubMed1984

Experimental production of bovine respiratory tract disease with bovine viral diarrhea virus.

Five 6-month-old calves were inoculated with bovine viral diarrhea (BVD) virus (n = 3) or Pasteurella haemolytica (n = 2) endobronchially with a fiberoptic bronchoscope. Five additional calves were inoculated sequentially with BVD virus followed by P haemolytica at a 5-day interval. Blood samples were collected daily from the calves for bacterial isolation. Clinical signs of respiratory tract disease in calves were recorded daily. If the calves survived, they were killed for necropsy 3 or 4 days after inoculation with P haemolytica (or 8 days after inoculation with BVD virus). The extent and nature of pulmonary lesions in the calves were determined, and the lower portion of the respiratory tract (lungs and trachea) was examined for both these organisms. The 3 calves, inoculated with BVD virus only, developed mild clinical signs mainly manifested as fever, nasal discharge, and occasional cough. Approximately 2% to 7% of the total lung capacity of these calves was pneumonic. Mild clinical signs and localized lesions involving about 15% of the lung volume developed in the 2 calves exposed to P haemolytica only. However, severe fibrinopurulent bronchopneumonia and pleuritis involving 40% to 75% of lung volume developed in the 5 calves inoculated sequentially with BVD virus and P haemolytica. The possible role BVD virus may have in bovine respiratory tract disease is discussed.

Animals↗
PubMed1989

Epidemiology of gastro-intestinal and respiratory tract diseases in rural areas of Varanasi (India).

The pattern of gastro-intestinal (GIT) and Respiratory tract (RTI) diseases in rural areas of the Varanasi district, U.P. (India) was studied from the outpatient (OPD) attendance between July 1985 to June 1986. Out of a total of new patients, 19.71% had respiratory diseases in contrast to 27.9% with GIT disease. A decreasing trend was observed in attendance rates as age advanced. The difference in age distribution of males and females was statistically significant. The attendance rates for GIT diseases were higher in female (29.16%) than in males (25.16%) whereas in RTI, the rates were higher in males (19.39%) than in females (18.77%). The attendance rate was found to be higher in rainy season (23.59%) followed by summer (14.50%). Diarrhoea (15.44%) and upper (URTI) respiratory tract infection (19.93%) occupied the major recorded episodes.

Adolescent↗
PubMed1987

[Examination and treatment of respiratory tract diseases in the horse in clinical practice].

In spite of regular vaccinations against equine influenza we are still observing a high rate of patients with respiratory problems in the equine practice. In our practice in Munich Riem, into which a horse clinic has been integrated, 4000 horses have been treated in 1985 alone. 874 of these showed some form of respiratory disease (= 22%). All of the 4000 horses have only been treated curatively, i.e. preventive forms of treatment such as vaccinations, deworming and examinations for insurance companies and prior to selling have not been taken into account. From 1983 until today in our clinic 256 horses with COPD had undergone clinical treatment. While out-patient horses had been treated for acute, subacute and chronic diseases of the respiratory system, in-patients were examined and treated for chronic respiratory disorders. Hospitalised horses had previously undergone treatment for varying periods of time. Apart from endemic or epidemic horse affections with signs of acute infections, the majority of patients treated belonged to a basically sound population. In the latter cases it is often just not possible to ascertain the individual causes of respiratory disease. Following documentation of the history of the present illness and after careful clinical examination including determination of breath frequency and type, lung auscultation and endoscopy (laryngoscopy, bronchoscopy), a symptomatic treatment of the horse is usually initiated. In cases of laryngitis or laryngotracheitis inhalations may be successful.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1989

Field trial of theophylline in cattle with respiratory tract disease.

A field trial was conducted to determine the efficacy of theophylline in relieving respiratory distress associated with bovine respiratory disease complex (shipping fever). Theophylline (as aminophylline capsules) was administered PO at a dosage of 28 mg/kg of body weight daily for 3 days to 20 calves with naturally acquired disease. Twenty similarly affected calves from the same group were given a placebo, and all calves were administered antibiotics concurrently. Respiratory rate and rectal temperature decreased and physical appearance improved in both groups of calves and was attributed to antibiotic administration or to natural remission of the disease. Five of the calves administered theophylline died; however, no calves administered the placebo died. Plasma theophylline concentration was greatly increased, compared with that determined in clinically normal calves in a pilot study. Bovine respiratory tract disease and/or concurrent antibiotic administration appear to cause such a rapid accumulation of lethal concentration of theophylline that its use should be restricted to hospitals capable of monitoring plasma theophylline concentration.

Administration, Oral↗
PubMed1990

Use of beta 2-adrenergic drugs in obstructive respiratory tract diseases of childhood.

The chemical structure and clinical application of beta 2-mimetic drugs used currently in obstructive respiratory tract diseases of childhood have been discussed. It has been pointed out that these drugs may be used as bronchodilators in manifesting obstruction and as prophylactic agents in chronic forms of such obstructive diseases. The aerosol forms of these compounds are the most effective but this route of administration meets some technical difficulties and cannot be used in children younger than 5-6 years. In the treatment of this age group, besides the tablet and elixir forms, the aerosol inhalation is the most useful. Selective slow-release beta 2-mimetics introduced about 25 years ago are successfully used in form of monotherapy or combination therapy in respiratory tract obstructions.

Adrenergic beta-Agonists↗
PubMed1987

Usefulness of chest radiographs in children with acute lower respiratory tract disease.

To determine how frequently and under what circumstances the chest radiograph changes pre-x-ray diagnoses and plans for management of suspected acute lower respiratory tract disease, experienced pediatricians performed a three-phased sequential evaluation (observation, history, physical examination), determined an initial diagnosis and the need for a chest radiograph after each phase, and recorded pre- and post-x-ray diagnoses and plans of management. Of the 102 children evaluated, the chest radiograph resulted in a change of the pre-x-ray diagnosis in 21% and pre-x-ray management plans in 16%. In the majority of these cases, a diagnosis previously considered less likely was "ruled in" or therapy was instituted rather than withheld. More important, when the pattern of decision making was consistent, with the initial diagnosis and the need for a chest radiograph remaining the same throughout all phases, the chest radiograph resulted in a change of pre-x-ray diagnosis in five (10%) of 48 patients, compared with a change in 16 (30%) of 54 when the pattern was inconsistent (P less than 0.02). Similarly, when the pattern was consistent, the pre-x-ray management was modified in only three (6%) of 48 patients versus 13 (24%) of 54 inconsistent cases (P less than 0.015). Chest radiographs are least useful when information from sequential observation, history, and physical examination is consistent in suggesting the same diagnosis and need for a chest radiograph. Radiographs appear to have greater impact on diagnosis and management when any inconsistencies arise.

Acute Disease↗
PubMed1977

Recovery of reovirus type 2 from an immature dog with respiratory tract disease.

Two similar cytopathic agents were recovered from the throat and rectal swab specimens of an immature dog with upper respiratory tract disease. The reference isolate, 14-72R, was shown to be a member of the reovirus group by its physicochemical properties, cytopathic effects in cell cultures, and appearance when examined in the electron microscope. Both isolates hemagglutinated human type O erythrocytes and antigenically were closely related to reovirus type 2. The affected pup had an increase in antibody titer to reovirus types 2 and 3. The latter findings provide evidence for possible heterotypic antibody responses in dogs to reovirus infection.

Animals↗
PubMed1995

Molecular characterization of Pasteurella testudinis isolated from desert tortoises (Gopherus agassizii) with and without upper respiratory tract disease.

Isolates of Pasteurella testudinis recovered from clinically healthy desert tortoises (Gopherus agassizii) and tortoises with upper respiratory tract disease (URTD) were characterized in an attempt to identify strains associated with disease. Eighty-nine isolates, 52 from ill and 37 from healthy tortoises collected from Nevada (USA), June 1990 to September 1991, were genomically fingerprinted and grouped based on ribotype similarity. Twelve isolates (six from ill and six from healthy tortoises) were further characterized with regard to whole-cell protein (WCP) and outer membrane protein (OMP) composition and their ability to survive in normal tortoise plasma. The 89 isolates were initially distributed into 33 distinct ribotype groups using the restriction enzyme EcoRI; five ribotypes contained over 50% of the isolates. Only one EcoRI ribotype was comprised of multiple isolates (n = 4) exclusively recovered from tortoises with URTD. When the ten EcoRI ribotypes that contained more than one isolate per ribotype were further studied using a second restriction enzyme, EcoRV, one EcoRI/EcoRV ribotype contained five isolates recovered from URTD tortoises and none from healthy animals. The EcoRI ribotype comprised of four isolates, all from tortoises with URTD, was further separated into three distinct groups with EcoRV. All 12 isolates studied grew equally well in normal tortoise plasma, and when broth-grown WCP and OMP profiles were evaluated, no proteins were unique to isolates from URTD tortoises. Iron-regulated OMP's were produced in three isolates examined, but these OMP's apparently were not virulence-related.

Animals↗