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Results for “SALIVARY GLAND DISEASES”

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PubMed1997

[The potentials of computed tomography in the diagnosis of salivary gland diseases].

Computer-aided tomography (CAT) was carried out in 68 patients with tumors of the salivary glands and 45 with sialolithiasis. CAT detected the tumors and located them, showed the type of the tumor (benign or malignant) and the tumor invasion. Sensitivity of CAT in tumors of the salivary glands was 97%, specificity 81.8%, accuracy 94.9%. In sialolithiasis CAT not only detected the concrements, but helped assess the status of the gland and the adjacent structures; its sensitively, specificity and accuracy were 95.5, 100 and 98.0%, respectively.

Adolescent↗
PubMed1977

Non-neoplastic salivary gland diseases in children.

Parotid enlargement in childhood is a diagnostic challenge to all physicians. A frame of reference has been established wherein the disease spectrum involving the child's parotid glands can be outlined in a stepwise manner. In some instances after sialography, specific hematologic tests, and cultures the diagnosis will remain obscure until a biopsy is performed. Protracted conservative management should be instituted prior to the consideration of ablative surgical procedures.

Adult↗
PubMed2002

The genu of the submandibular duct--is the angle significant in salivary gland disease?

OBJECTIVES: To investigate whether the angle of the genu of the submandibular duct is a significant contributory factor in the development of salivary calculi or sialoadenitis. METHODS: A preliminary test with a phantom was performed, taking oblique lateral views with different vertical and horizontal beam angulations to assess the effect on the genu angle. The phantom comprised a dried mandible and a piece of wire bent to simulate the submandibular duct. There were no differences in the measured angle of the bend in the wire within the range of beam angulations used in the clinical study. One hundred and two sialographs were analysed from three separate groups of patients, normal controls (n=18), proven salivary calculi (n=61) and those with sialoadenitis (n=23). The oblique lateral radiographs were digitised and imported into the Denoptix digital system, and the angle measured using the VixWin 2000 software. Differences in angle between groups were investigated using analysis of variance. RESULTS: The mean angle of the genu was 103 degrees (range 41 degrees-147 degrees) in the control group, 108 degrees (range 46 degrees-178 degrees) salivary calculi group, and 91 degrees (range 24 degrees-155 degrees) in sialoadenitis patients. There were no statistical differences in the angle between the groups. CONCLUSIONS: There is a wide variation in the angle of the genu of the submandibular duct (24 degrees -178 degrees ). This angle does not appear to be associated with either sialolithiasis or sialoadenitis.

Adolescent↗
PubMedDate not supplied

[Cytomegalovirus isolation in chronic salivary gland diseases of adults].

The results of virological investigation of a rare clinical instance of familial disease with a localized form of cytomegalovirus infection which, as a rule, is not diagnosed in life are presented. The infection localized in the salivary glands was the source of generalization of the process with a high fever, eruptions, lymphadenopathy, inflammatory changes in the excretory ducts of the salivary glands. Exacerbation of the chronic process was accompanied with high antibody titres (1:256--1:1024) with inhibition of the cellular immunity reactions in the mother. The latent form of infection in the father and two daughters ran without clinical manifestations, with low antibody titres and moderate inhibition of cellular reactions. The isolated strains of cytomegalovirus were identical in all the subjects under study and antigenically close to the Ad-169 strain.

Adult↗
PubMed1987

[Computed tomography and diagnosis of salivary gland diseases].

A study was carried out to compare routine sialography and combination sialo-CT. The results in 36 patients with afflictions of the parotid and submandibular region are discussed. In addition to tumors, regarded as primary indications, inflammatory disorders were also considered. The diagnosis made by routine sialography is regularly confirmed by computed sialography (CTS), which is often an important complementary means. Visualization of the deep parotid lobe and parapharyngeal space (third plane) is very important for making the diagnosis and planning therapy.

Humans↗
PubMed1997

Lupus erythematosus profundus around the salivary glands: a case resembling submandibular salivary gland disease.

In a 29 year old Japanese woman with SLE, a bilateral submandibular mass was detected. Computed tomographic (CT) scan suggested inflammatory changes around the submandibular glands. Histological findings of the deep skin biopsy showed typical changes of lupus erythematosus profundus (LEP). LEP should be considered in the differential diagnosis of an unexplained submandibular mass in a subject with SLE.

Adult↗
PubMedDate not supplied

[Treatment of inflammatory salivary gland diseases by using intraductal UV irradiation].

A novel technique is offered for treatment of sialadenitis. Ultraviolet irradiation conductors are inserted into the gland via its major duct for subsequent intracorporeal UV therapy of the gland. The results of the treatment are analyzed in 57 cases of sialadenitis observed during 1 to 2.5 years. The technique proved effective enough to be recommended for practical application.

Brachytherapy↗
PubMedDate not supplied

[Comprehensive radiologic examination in the diagnosis of parotid salivary gland diseases].

Comprehensive x-ray, ultrasonic and radionuclide examinations of 131 patients with chronic sialadenitis (n = 50), sialosis (n = 59), sialolithiasis (n = 9), autoimmune disorders (n = 6), and bulky processes (n = 7) of the parotid salivary glands were carried out. The diagnostic potentialities of each method in every of these conditions were analyzed. No correlation between the structural and functional disorders of the parotid glands could be traced. A complex of radiologic methods is necessary to fully assess the anatomic and functional status of the parotid glands. An algorithm of examination in such conditions is presented.

Adolescent↗
PubMed1978

Alterations in lactoferrin in salivary gland disease.

During the active phase of chronic recurrent parotitis there is a marked elevation in the parotid concentration of lactoferrin (Lf), and iron-binding glycoprotein with antibacterial properties. The Lf concentration decreases during the recovery period, but still remains above normal levels. The changes of Lf in parotitis parallel recent findings in mastitis and pancreatitis. Elevations in Lf were also noted in five of six subjects with Sjögren's disease, but not in subjects with sarcoidosis, diabetes or "dry mouth" without sialographic changes. The source of the Lf has not been determined; it could arise in part from disrupting polymorphonuclear leucocytes and in part from epithelial cells that synthesize Lf in the salivary glands. Inflammatory stimulation of Lf synthesis would suggest a basic protective mechanism in exocrine glands and should be fully explored.

Albumins↗
PubMed2005

Major salivary gland diseases. Multicentre study.

This multicentre study involved 28 Italian ORL Centres responding to a questionnaire sent by us which allowed recruitment of a high large number of cases of parotid neoplasms observed over a 10-year period. Statistical data obtained partly confirmed previous findings. Benign tumours account for 80% of case histories with a relationship 1:4 M/F, the most frequent being pleomorphic adenoma (57.3% of cases), followed by Warthin's tumour (32.4%), this rating not having been confirmed in case histories (8-10%) in the literature. Malignant tumours instead were fewer in number compared to the literature (14% vs 25-30%); the most frequent being mucoepidermoid carcinoma (18.2%) of which 44% G1, 33% G2 and 23% G3. Adenoid-cystic carcinoma was observed in 15.3% and < or = 10% for all the other most frequent histological malignant neoplasms. Diagnostic work-up included echotomography and fine-needle aspiration biopsy, less used imaging techniques were computed tomography, magnetic resonance imaging, Sialo-computed tomography. During this multicentre investigation more widespread use of imaging techniques has, however, been observed. The greater use of ecotomography and of fine-needle aspiration biopsy was due to simplicity of application and low cost offering good sensitivity and specificity. Surgical treatment of benign tumours consisted, in 50% of cases, in superficial paroditectomy and in approximately 30% of total paroditectomy. Enucleoresection was limited to approximately 15% of neoplasms, enucleation to <10% of cases with only 2% of pleomorph adenoma due to the well-known anatomo-pathological characteristics which may lead to relapse. For malignant neoplasms, total parotidectomy was performed in approximately 50% of cases, while in the remaining 50% an almost equal rate of superficial parotidectomy was carried out and enlarged parotidectomy, with or without sacrificing the facial nerve, which was rebuilt in 60% of cases. The lateral neck dissection most frequently carried out was of functional type in 54% and selective type in 46% with removal of levels I-III and II-IV in approximately 60% of cases. Sentinel lymph node was observed in a limited number of centres. When no clinically evident lymph nodes were present (NO) considering the tumour histotype, two thirds of patients underwent surgery or radiotherapy, while in the remainder the wait-and-see attitude was prefered. Post-operative-complementary radiotherapy was very frequently performed instead of chemotherapy. Oncological results obtained were compared with those reported in the literature: in fact for all benign neoplasms relapse ratings are about 5%, while for malignant tumours the worst prognosis was in squamous cell carcinoma with median of 37.7 on survival and metastasis rate of 16.5%. Finally, mucoepidermoid carcinoma tumours showed best survival, followed by adenoid-cystic carcinoma with ranges, respectively, 83 and 81.

Adult↗