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The demographics of slipped capital femoral epiphysis. An international multicenter study.

One thousand six hundred thirty children with 1993 slipped capital femoral epiphyses were reviewed; 41.2% were girls and 58.8% were boys. There were 47.5% white, 24.8% black, 16.9% Amerindian, 7.4% Indonesian-Malay, 2.1% Native Australian/Pacific Islands, and 1.3% Indo-Mediterranean children. The diseased hip was unilateral in 77.7% and bilateral in 22.3% of the children, and chronic in 85.5% and acute in 14.5% of the children. Of the unilateral slips, 40.3% involved the right hip and 59.7% the left hip. The child's weight was greater than or equal to the ninetieth percentile in 63.2% of the children. The average age for the girls and boys was 12 and 13.5 years. The age at diagnosis decreased with increasing obesity. The youngest children were the Native Australian/Pacific Island children (11.8 years) and the oldest were the white and Indo-Mediterranean children (13 years). The Indonesian-Malay and Indo-Mediterranean children were the lightest in weight, and the black children the heaviest. The Indo-Mediterranean children had the highest proportion of boys (90.5%), and the Native Australian/Pacific Island children the lowest (50%). The highest percentage of bilaterality was in the Native Australian/Pacific Island children (38.2%), and the lowest in the Amerindian children (16.5%). The relative racial frequency of slipped capital femoral epiphysis compared with the white population was 4.5 for the Polynesian, 2.2 for the black, 1.05 for the Amerindian, 0.5 for the Indonesian-Malay, and 0.1 for the Indo-Mediterranean children. In children with unilateral involvement, the age at presentation was younger for those children in whom bilateral disease later developed (12 versus 12.9 years old). In 82% of the children with sequential bilateral slips, the second slip was diagnosed within 18 months of the first slip.

Adolescent↗

Factors correlated with caraniomandibular disorders in young and older adults.

This study was conducted to examine prevalence of craniomandibular disorders in young adults compared with that in older subjects. In addition, the relationship between various oral conditions and this dysfunction was studied. No difference was found in the incidence of craniomandibular disorders between the groups. Classification according to the Helkimo index showed significant difference in complaints of craniomandibular disorders symptoms between the groups. Most of the older patients did not complain of mild disorders. The results suggest that conditions such as the number of teeth, presence or absence of dentures, and the type of denture worn are not important factors in the pathogenesis of craniomandibular disorders.

Adult↗

Improving procedures for recording suicide statistics.

OBJECTIVE: To explore the changing relationship between rates of suicide and undetermined death in Britain and Ireland. DESIGN: Longitudinal analysis of the official statistics relating to unnatural deaths in England and Wales and the Republic of Ireland between 1976 and 1992. MAIN OUTCOME MEASURES: Male and female rates of suicide and undetermined deaths for Ireland and England and Wales, age adjusted to the standard world population. Ratio of undetermined deaths to suicide. RESULTS: The official Irish male suicide rate is now much higher than that of England and Wales while the female rates are broadly similar. The rate of undetermined deaths has risen amongst English males and remained stable for females but has significantly fallen off among both Irish males and females. The proportion of deaths classified as 'undetermined' is now very much less in Ireland than in England and Wales. DISCUSSION: National plans for suicide prevention in either country cannot be properly audited unless improved procedures are put in place to increase the validity and reliability of the official suicide figures. Each country could beneficially learn from the other in this regard.

Adolescent↗

Waist-hip ratio and blood pressure correlation in an urban Indian population.

Truncal obesity judged by increased waist-hip ratio (WHR) is an important risk factor for atherosclerosis. One of the mechanisms postulated by which truncal obesity increases coronary risk is high blood pressure (BP). Studies of correlation of WHR with systolic and diastolic BP have shown conflicting results. A study on 443 persons (250 males, 193 females) for WHR measurement during a comprehensive cardiovascular survey in an urban population of Rajasthan was undertaken. The mean WHR in males was 0.90 +/- 0.07 and in females 0.87 +/- 0.08. The median value was 0.91 in males and 0.88 in females. Correlational analysis of WHR with anthropometric and clinical parameters showed that in males there was a positive relationship of WHR with weight (r = 0.11), body mass index (r = 0.13) and systolic (r = 0.11) and diastolic BP (r = 0.11) but not with age and height. In females no significant relationship was seen with these variables. When classified according to the US Fifth Joint National Committee (JNC-V) recommendations for diagnosis of truncal obesity (WHR males > 0.95, females > 0.85) it was seen in 42 (17%) males and 131 (68%) females. Sub-analysis of these two groups showed that mean values of systolic and diastolic BP were not significantly different in truncally obese subjects. However, stratified analysis after classifying WHR in four groups (WHR < 0.85, 0.85-0.89, 0.90-0.95 and > 0.95) showed that in males there was a significantly rising trend of weight, body mass index, systolic and diastolic BP with increasing WHR. WHR of > or = 0.85 was associated with higher systolic and diastolic BP.

Adult↗

Prevalence of malocclusion traits in an Australian adult population.

The prevalence of certain malocclusion traits in an Australia adult population was examined in a sample of 113 female and 103 male adult subjects aged between 18 and 64 years (average age = 38.1 years). If cross-sectional studies of younger population groups are to be used for research into the long-term physiological effects of malocclusion, it is essential to know if certain and specific malocclusion traits are stable over time. In this cross-sectional study, the prevalence of many malocclusion traits did not change; however, with advancing age, the incidence of posterior crowding, posterior rotations, posterior crossbite and anterior irregularity increased significantly.

Adolescent↗

Blood lead in U.K. children--time for a lower action level?

1. Blood lead measurements in samples collected from 660 London schoolchildren during 1991 to 1992 suggest that the blood lead values in children in the U.K. are decreasing. 2. Geometric mean values for blood lead were 0.18 (range 0.05-0.71) micromol/l [3.7 (1. 0-15.0) microgram/dl]. Analysis of variance showed differences between ethnic groups, sex and schools. An age-matched subset of 148 children was compared with 136 children from an earlier study in 1986 and 1987. Trend analysis of the geometric mean lead values showed a negative slope (b=-0.484, P<0.0001), with maximum values of 0.81, 1.00, 0.71 and 0.43 micromol/l (17, 21, 15 and 9 microgram/dl) for the years 1986, 1987, 1991 and 1992 respectively. 3. It is recommended that children in the U.K. being investigated for anaemia, pica, recurrent abdominal pain or a high-risk environment should have blood lead values measured and that the action level for blood lead in children should be decreased from 1.19 micromol/l to 0.48 micromol/l (from 25 microgram/dl to 10 microgram/dl). 4. Guidance is offered to clinicians and other health professionals investigating excessive lead exposure.

Adolescent↗

Variations in angioplasty and bypass surgery.

OBJECTIVES: This article describes rates of and times to revascularization procedures for heart attack patients. DATA SOURCE: The data are from Statistics Canada's Person-Oriented Information Data Base. Hospital discharge records for heart attack patients were linked for fiscal years 1992/93 and 1993/94. ANALYTICAL TECHNIQUES: Hospital patients admitted between April 1 and September 30, 1993 with a primary diagnosis of acute myocardial infarction (AMI) were followed for six months to determine what percentage underwent percutaneous transluminal coronary angioplasty and/or coronary artery bypass graft surgery. Analyses of time-to-procedure were performed for those patients who had not been hospitalized for AMI in the previous 12 months. MAIN RESULTS: Approximately 24,000 Canadians were discharged from hospital during the first half of fiscal year 1993/94 with a diagnosis of AMI. Within six months, 8.7% had an angioplasty and 6.7% had a bypass; overall, 14.9% were revascularized. Women were less likely than men to have a bypass, but angioplasty rates did not differ significantly. The rate of revascularization declined with age. After adjusting for age and sex, rates were higher in the western provinces.

Adult↗

Signs and symptoms of temporomandibular disorders in 19-year-old individuals who have undergone orthodontic treatment.

Fifty-five per cent of the 1554 19-year old subjects in Halmstad, Sweden, born in 1975, have received orthodontic treatment. Among these, 520 have been treated by specialists (specialist group) and 340 by general practitioners after consultation with specialists (consultation group). The aims were to study the prevalence of signs and symptoms of temporomandibular disorders (TMD) in these two groups on a long-term basis, to identify any possible difference between the groups, and to compare the results with those from a previously presented epidemiological study (control group). From the population of orthodontically treated subjects, a sample was randomly selected to represent the two groups, and 260 subjects agreed to attend for investigation, the participation rate being 77%. The investigation consisted of a questionnaire and clinical examination focusing on function and dysfunction of the masticatory system. Severe signs and symptoms of TMD were rare, the prevalence did not differ significantly between the two orthodontic groups, and the results were similar in the control group. The prevalence of several signs and symptoms was more common in females than in males. No significant correlation between TMD signs and symptoms and occlusal contact recordings was found. It was concluded that the vast majority of the 19-year old individuals who had undergone orthodontic treatment had well-functioning masticatory systems, and severe signs and symptoms of TMD were rare.

Adult↗

Urinary 1-hydroxypyrene as a marker of exposure to pyrene: an epidemiological survey on a general population group.

Urinary levels of 1-hydroxypyrene in a general adult population group are studied. Experimental data are not normally distributed; statistical analysis required a base 10 logarithmic transformation of data. The concentrations of urinary 1-hydroxypyrene measured were expressed as microgram g-1 urinary creatinine and are comparable with those reported by other authors, both for smoker and non-smoker subgroups. Multiple regression analysis shows that, for smokers, the number of cigarettes smoked per day and the body mass index (BMI) significantly influence the levels of urinary 1-hydroxypyrene expressed as microgram g-1 urinary creatinine, whereas no personal or behavioural variable (age, sex, alcohol consumption, dietary intake of pyrene, BMI) modified the 1-hydroxypyrene levels for non-smokers.

Adult↗

Birthweights in Goroka and Kainantu Hospitals.

Birthweight data for 4474 live, healthy, singleton, full-term births of 2000g or over were analysed. The mean birthweights were 3136 +/- 445g at Goroka, and 3106 +/- 473g at Kainantu. Birthweights varied with sex, region of maternal origin, season and birth order, but not with year. Significant influences on Goroka birthweight values were, in order of importance, birth order, sex and season.

Birth Order↗

[Magnesium, calcium, zinc, potassium, total and HDL cholesterol and total creatine kinase in 37 cases of instable angina: a correlation study].

Plasma and erythrocyte magnesium (P-Mg, E-Mg), zinc (P-Zn, E-Zn) and potassium (P-K, E-K), plasma calcium (P-Ca), HDL-cholesterol and total cholesterol and total creatine kinase (TCK) were determined in 37 cases (26 men, 11 women) of unstable angina pectoris (UAP) on the first day of hospitalization. The same variables, except P-K and TCK, were measured in 58 male and 53 female reference subjects. The methods of measurement were emission spectrometry for K, atomic absorption spectrometry for Mg, Ca and Zn, and the R CK NAC-activated Merckotest for TCK. According to the normality of distributions, statistical analysis of results was performed either by parametric or nonparametric tests. Multiple (R), simple (r) and Spearman (rs) correlation coefficients were calculated, and only significant correlations (p less than or equal to 0.05) were accepted. There was no significant R for UAP patients. For UAP men, r was negative and significant between P-Mg and E-K, but positive between P-Ca and P-Zn, as for reference subjects; and rs was negative and significant between P-Zn and TCK. For UAP women, only rs was positive and significant, between P-Mg and TCK. In the UAP population, contrary to the reference population, there were no significant differences relative to sex. In comparison with reference men, UAP men presented a significant (p less than 0.005) increase in E-Mg and significant (p less than 0.001) decreases in P-Ca and P-Zn.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Estimating age-related trends in cross-sectional studies using S-distributions.

Growth trends in children are often based on cross-sectional studies, in which a sample of the population is investigated at one given point in time. Estimating age-related percentiles in such studies involves fitting data distributions, each of which is specific for one age group, and a subsequent smoothing of the percentile curves. The first requirement for this process is the selection of a distributional form that is expected to be consistent with the observed data. If a goodness-of-fit test reveals significant discrepancies between the data and the best-fitting member of this distributional form, an alternative distribution must be found. In practice, there is seldom an objective argument for selecting any particular distribution. Also, different distributions can yield very similar fits, so that any selection is somewhat arbitrary. Finally, the shapes of the observed distributions may change throughout the age range so drastically that no single traditional distribution can fit them all in a satisfactory manner. To overcome these difficulties in population studies, non-parametric smoothing techniques and normalizing transformations have been used to derive percentile curves. In this paper we present an alternative strategy in the form of a flexible parametric family of statistical distributions: the S-distribution. We suggest a method that guides the search for well-fitting S-distributions for groups of observed distributions. The method is first tested with simulated data sets and subsequently applied to actual weight distributions of girls of different ages. As far as the results can be tested, they are consistent with observations and with results from other methods.

Adolescent↗

Normative and reliability data for the Children's Depression Inventory.

The present study was undertaken to examine some of the psychometric properties of the Children's Depression Inventory (CDI), a self-report inventory devised by Kovacs and Beck (1977) to measure depression in children and adolescents. Normative and reliability data were obtained from three independent samples taken from eight public schools in central Pennsylvania. Age- and gender-related differences in reported characteristics of depression were also investigated. The subjects were 594 males and 658 females whose ages ranged from 8 to 16 years and whose combined mean age was 11.67 years (SD = 1.91). The CDI was group-administered to all 1,252 subjects; 155 fifth-grade subjects (77 males and 78 females) were retested after 3 weeks, and 107 seventh- and eight-grade subjects (45 males and 62 females) were retested after 1 year. The distribution statistics for the combined samples yielded an overall CDI mean of 9.09, a standard deviation of 7.04, and a cutoff score of 19 for the upper 10% of the distribution. Reliability assessed through coefficient alpha, item-total score product-moment correlations, and test-retest coefficients proved acceptable. Gender differences were obtained for several item-total score correlations and for test-retest reliability of CDI scores.

Adolescent↗