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[Comparative evaluation of the treatment of radiation skin injuries with oxycort ointment and Peruvian balsam].

The regenerating action of Peruvian balm and oxycort was compared in experiments on rats with experimental radiation skin injuries. Radiation skin ulcers entailed severe morphological and biochemical abnormalities, there was also observed an unstable healing provided the treatment was not applied. Oxycort ointment slightly reduced the period of healing. However, formation of secondary microdefects was conducive to recurrent ulcer in the future. Peruvian balm exerted a pronounced bactericidal action, strongly intensified the reparative processes, and, therefore, reduced the period of healing and favoured the differentiation of the cicatricial tissues that led to a stable healing of the ulcers.

Administration, Topical↗
PubMed1991

Canada balsam.

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Canada↗
PubMed2002

Alpha-glucosidase inhibitor from the seeds of balsam pear (Momordica charantia) and the fruit bodies of Grifola frondosa.

Alpha-glucosidase inhibitory activities were found in aqueous methanol extracts of the seeds of Momordica charantia and the fruit bodies of Grifola frondosa. An active principle against the enzyme prepared from rat small intestine acetone powders was isolated and characterized. The structure of the isolated compound was identified as D-(+)-trehalose by FDMS, 1H-, 13C-NMR, and [alpha]D measurements. The inhibitory activity of trehalose was compared with 1-deoxynojirimycin. Trehalose showed 45% inhibitory activity at the concentration of 2 x 10(-3) m, but 1-deoxynojirimycin had 52% inhibitory activity at 1 x 10(-7) M.

1-Deoxynojirimycin↗