[Blood capillaries and otorhinolaryngology. V. Ionization in otorhinolaryngology].
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The cardiovascular effects of the ingestion of ethyl alcohol are determined by the amount consumed and time factors as well as the nutritional status of the individual. Acute alcoholism produces various cardiac manifestations that are related primarily to the concentration of alcohol in the blood. Chronic alcoholism is associated with three identifiable cardiovascular syndromes that have been designated alcoholic myocardosis, nutritional heart disease and beriberi heart disease. Differentiation is indicated because of their respective distinguishing diagnostic features and prognostic implications. The therapeutic effects of alcohol in coronary artery disease are apparently attributable to cerebral responses rather than demonstrable increase in coronary blood flow.
Penicillin remains the most useful antibiotic for treatment of infections due to organisms sensitive to this drug because of its bacteriocidal properties and its freedom from toxicity. Enormous doses may broaden its antibacterial spectrum and it may act synergistically with certain other drugs. New penicillin compounds have been developed which serve such special purposes as (1) concentration in lung tissue, (2) maintenance of therapeutic concentrations in the blood for long periods after injection, (3) avoidance of allergic reactions and (4) prolongation of therapeutic content in the blood after oral administration. Erythromycin and carbomycin may be effective against bacterial infections not sensitive to other antibacterial drugs. Streptomycin combined with dihydrostreptomycin is less toxic than is either drug used alone. Isoniazid is a valuable antituberculosis drug, especially when combined with streptomycin.Viomycin may be useful in treating tuberculous infections that have become resistant to other specific drugs.