SEARCH · PubMed Health

Results for “Body Weight--changes”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 199 records · Page 11Linked to original sources

PubMedDate not supplied

[Parenteral hyperalimentation in patients with advanced neoplastic disease (author's transl)].

Two groups of patients suffering from advanced neoplastic disease were fed parenterally for a period ranging from 1 to 16 weeks. The parameters considered were: weight change, serum albumin level, lymphocyte transformation test and serum immunoglobulin level. There were 23 patients in one group and 21 patients in the other. Regimens included for group I: saline solution (1000-1500 ml), glucose (100-150 g) and amino acids (15-30 g) per day; for group 2: 40-50 Cal/kg per day (dextrose about 15 g/kg per day), about 2 g of amino acids/kg/day and about 40-50 ml water/kg/day. In addition, 13 patients underwent both treatments sequentially. All the Group I patients lost weight (1.3 kg/week); while out of 23 patients in Group 2, 15 gained weight, 2 remained unchanged and 6 continued to lose weight, but to a lesser rate than before hyperalimentation (the average weight gain was 1.1 kg/week). Serum albumin levels decreased in 19 out of 25 patients in Group I and increased in 14 out of 26 patients of Group 2. Initial values of the lymphocyte blast transformation test were very low in both groups of patients, and an increase was observed only in patients treated by hyperalimentation. The increase was more evident in patients who were not under antiblastic treatment. Changes in serum immunoglobulin levels were not significant. The authors conclude that malnutrition plays a very important role in neoplastic cachexia and can be improved by parenteral hyperalimentation. Although it is possible that in the near future hyperalimentation and conventional neoplastic therapies will play complementary roles in treatment of advanced neoplastic disease, malnutrition is still the specific indication for intravenous hyperalimentation.

Amino Acids↗

PubMed1975

Spleen and liver weight changes in NZB mice with haemolytic anaemia.

Spleen and liver weights from 998 NZB mice were subjected to computerised multivariate analysis. 3-dimensional graphs relating predicted spleen and liver weights to age and bodyweight were prepared and the relationship of the fitted surface to the histology and pathological autoantibody is discussed. On the basis of spleen weight increase, red-cell destruction throughout the greater part of life seems to be mainly intrasplenic, while intrahepatic destruction does not become important until later, when it is probably a dominant feature in the terminal period of the disease. Only limited organ weight increases occur in breeding females, and it is suggested that pregnancy lessens the effect of the haemolytic disease, the 'protective' effect extending long after the cessation of breeding.

Anemia, Hemolytic, Autoimmune↗

PubMed1978

An index for assessing weight change in children: weight/height ratios.

Weight and height data from two studies were recomputed, and original data were computed using a Weight Index formula that accounts for the interaction of actual weight/height changes in growing children and compares this ratio with that of normed weight/height ratios for equal-aged children. Recomputing the data of one study showed that the Weight Index is a more sensitive procedure for assessing long-term behavioral treatment of obesity for girls than weight alone. Recomputing the data of a second study showed that the Weight Index formula is consistent for boys and girls and is a more sensitive procedure for assessing long-term effects of a variety of medical treatments for obesity than the Ponderal Index or weight alone. Computation of the data for 17 "normal" children in a preschool class showed a zero Weight Index score before and after a six-month interval elapsed without treatment. The procedure may be useful in assessing ponderosity or anorexia over intervals of six months or more with growing children or difference between actual and normed weight over shorter intervals.

Adolescent↗

PubMed1992

Adolescent smoking, weight changes, and binge-purge behavior: associations with secondary amenorrhea.

BACKGROUND: The association of secondary amenorrhea with extreme forms of substance use, weight control, and exercise in nonrepresentative samples raises questions as to whether adolescents in the general population who engage in these behaviors are at increased risk for secondary amenorrhea. We examined the prevalence and behavioral correlates of secondary amenorrhea in a county-wide high school population of 2544 girls aged 13 to 18. METHODS: A survey questionnaire, which elicited menstrual history as well as weight history, weight control practices, level of exercise, and use of cigarettes, wine, and beer, was administered during school hours; absentees were also surveyed. The completion rate was 91%. RESULTS: The 1-year prevalence of secondary amenorrhea was 8.5%. Secondary amenorrhea was associated with smoking one or more packs of cigarettes per day (adjusted relative risk [RRa] = 1.96, 1.21-3.10), with multiple binge-eating behaviors in combination with laxative use or self-induced vomiting (RRa = 4.17, 2.54-6.32), and with weight fluctuation due to weight control (RRa = 2.59, 1.33-4.79). There was no association between amenorrhea and alcohol consumption or exercise level. CONCLUSIONS: Estimates of attributable risk are provided and indicate that bulimic behaviors and cigarette smoking may result in a considerable excess of cases of secondary amenorrhea in an adolescent population.

Adolescent↗

PubMed1992

Feeding wash water solids to sows during gestation and lactation: sow productivity, pig performance, and tissue compositions.

Diets containing 0, 10, or 20% dried wash water solids (WWS) from a milk processing plant were fed to 54 Yorkshire gilts (160 to 270 kg) for five parities. Feed intake, weight changes, and morbidity of sows were measured; number of pigs per litter, birth weight, and weight gain of pigs were also determined. Blood, tissue, and milk samples were taken from sows for hematological and mineral analyses, and tissue samples were taken from newborn pigs from each treatment per parity. Overall, initial sow weight, sow weight at weaning, and weight losses were not affected (P greater than .05) by treatment. At 107 d of gestation, overall weights decreased (P less than .05) linearly with level of WWS in the diet. The number of pigs per litter and weight of pigs were not affected (P greater than .10) by diet. Concentrations of NA (P less than .10) and Cd (P less than .05) were lower in kidney of sows fed 20% WWS, and concentrations of Zn were lower in bone and in kidney of sows fed the 20% WWS diet. The Sr and Ba concentrations increased (P less than .05, P less than .10) linearly in bone from sows with level of WWS in the diet. In pigs, concentrations of Mn in kidney and Zn in liver were lower for the 20% WWS treatment. In conclusion, feeding WWS to sows over five parities had minimal adverse effects on sow productivity and pig performance; the reduction in Zn concentrations in tissues of sows and pigs seemed to be related to the Ca content of WWS.

Animal Feed↗

PubMed1992

Etiology of acetonemia in Norwegian cattle. 1. Effect of ketogenic silage, season, energy level, and genetic factors.

Plasma acetoacetate concentration in the 1st mo of lactation and its relation to BW change, milk yield, DMI, and BW postpartum were studied in 361 first lactation cows during 6 yr. The cows were fed concentrate at 6 and 3 kg/d. Calvings took place from August to December. Single observations for all cows were fitted by a multitrait animal model that accounted for all genetic relationships. Heritability for acetoacetate was .11 with a genetic correlation of .87 for milk yield, -.65 for weight change, and -.13 for BW postpartum. Acetoacetate was higher at 3 kg/d of concentrate than at 6 kg/d, and calving after 3 to 4 mo of indoor feeding was related to higher acetoacetate than was calving shortly after the pasture season. Acetoacetate was related to weight loss postpartum, but at a different degree in different years. In some years, compounds of the silage caused strongly elevated plasma concentrations of acetoacetate after feeding. Experiments were performed to compare hay with silages of different qualities. Rumen concentration of different amines 3 h postfeeding was taken as an index of the amine load of the cow. The concentration of several amines in rumen fluid were high after feeding ketogenic silage.

Acetoacetates↗

PubMed1978

The metabolic and endogenous energy losses of adult roosters.

The metabolic plus endogenous energy losses of 300 adult, White Leghorn roosters during a 24 hr period, following 24 hr of starvation, were measured. The losses ranged from 2.37 to 6.93, with a mean of 4.46, kcal/kg body weight/24 hr. Multiple regression analysis showed that only 23% of the variation in the loss/bird/24 hr was explained by differences in body weight and weight change. The measurements were made during 38 experiments spread over 3 years but there was no evidence of any relationship between the year or time of year and magnitude of the energy loss.

Animals↗

PubMed1992

Oestrogen and cyclical progestogen in postmenopausal hormone replacement therapy.

OBJECTIVE: To ascertain the effectiveness, safety and incidence of side effects of a postmenopausal hormone replacement regimen consisting of continuous conjugated equine oestrogens and cyclical medroxyprogesterone acetate given for the first 14 days of each calendar month. DESIGN: A six month, prospective, open label, two centre, outpatient study of continuous Premarin (0.625 mg; Wyeth-Ayerst) and cyclical Provera (10 mg; Upjohn). Dosage adjustment was allowed in one centre. STUDY POPULATION: Seventy-six postmenopausal women in Adelaide and Brisbane. MAIN OUTCOME MEASURES: Menopausal symptom score, serum lipid levels, routine biochemical and haematological indices, endometrial histology and clinical bleeding pattern, blood pressure, weight changes, side effects, withdrawal from the study, compliance and necessary dose adjustment. MAIN RESULTS: Eight women withdrew from the study and nearly 50% experienced some minor side effect. Where dosage adjustment was allowed, almost all side effects were eliminated. Most patients had acceptable regular withdrawal bleeds although some were deemed heavy. There was a statistically highly significant 54% reduction in the menopausal symptoms score at three months and a 62% reduction at six months. Endometrial biopsy at six months showed atrophic or secretory endometrium with no inappropriate proliferation or hyperplasia. Total cholesterol and low density lipoprotein (LDL) cholesterol levels were significantly decreased. The high density lipoprotein (HDL) cholesterol level remained unchanged and triglyceride levels were raised within the normal range. There were no other clinically relevant biochemical, haematological or clinical changes. CONCLUSION: Continuous conjugated equine oestrogens (0.625 mg) and cyclical medroxyprogesterone acetate (10 mg) for the first 14 days of each calendar month proved to be a safe and effective postmenopausal therapy regimen. Initial minor side effects were common but could be readily ameliorated with early follow-up and dose titration.

Adult↗

PubMed1976

[Hypolipidemic effects of DH581 during prolonged administration (author's transl)].

A new cholesterolol lowering agent, DH581, has been studied in eighteen patients with elevated cholesterol levels for more than one year. The data showed twelve patients studied as being cholesterol responders with an overall decrease of 21%. The Placebo period had an overall rise in cholester with a return of effect after re-administration of the drug. During the remainder of the study period, responders had a 17% decrease in cholesterol. Non-responders varied widely but did not demonstrate a significant cholesterol decrease. Triglyceride levels demonstrated wide fluctuation. Nine responders of eighteen patients studied had an overall decrease of 32% and the remainder demonstrated an increase in triglyceride values. Weight changes were not significant and did not account for the observed changes. There was no consistent relationship of sex to the observed response. DH581 appears to be effective antyhypercholesterolemic drug of low toxicity.

Adolescent↗

PubMed1979

[Effectiveness of a preventive mass examination for cardiac risk factors (author's transl)].

18 months after a mass examination for coronary heart disease risk factors in employees of a large industrial firm, 75% of the subjects examined at that time were re-interviewed and measurements of blood pressure and weight repeated. Despite an altogether inadequate longterm control of the risk factors detected, a part of the subjects examined had drawn consequences regarding their way of life by reducing weight, changing smoking habits and increasing physical activity, thus proving the effectiveness of information and advice received in a screening investigation. In about 40% of the overweight subjects a reduction in weight and in half of the hypertensives a lowering of blood pressure to values below 160/95 mmHg was noted.

Adult↗

PubMed1979

Determination of the caloric requirement of patients with cancer.

The weight change of 16 adult patients with cancer receiving total parenteral nutrition for an average period of 12 days was evaluated. The nitrogen to calorie ratio of the hyperalimentation fluid ranged from 1:144 to 1:235. The amount of nonprotein calories delivered was expressed as a multiple of the resting metabolic expenditure, and patients were divided according to the following different rates of calories delivered/resting metabolic expenditure into three groups: group 1, 1.11 to 1.48, mean 1.33; group 2, 1.55 to 1.76, mean 1.67, and group 3, 1.78 to 2.10, mean 1.87. The weight change in group 2 patients, +0.32 kilograms per day, was statistically different from that of group 1 patients, p less than 0.01, but not from that of group 3 patients. We conclude that the optimal hyperalimentation infusion rate to achieve weight gain in patients with cancer includes 50 nonprotein calories per kilogram per day as well as 1.5 grams of amino acids per kilogram per day with a nitrogen to calorie ratio of 1:208.

Adenocarcinoma↗

PubMed1992

Parity-related weight change in women.

Pregnancy is thought to be a major contributor to the excess prevalence of obesity in women compared to men. Pregnancy-related increases in weight are purported to increase the risk that women will develop chronic diseases associated with high body weight. The assertion that pregnancy is associated with permanent weight gain and overweight was examined among 41184 post-menopausal women participating in a population-based study. Women reported lifetime parity, weight at ages 18, 30, 40 and 50 years, and current height. Body weight and body mass index (BMI) increased with age. On average, women gained 11.05 kg, or 0.35 kg per year between the ages of 18 and 50 years. Parity was associated with an increase in body weight from age 18 to 50 years of 0.55 kg per live birth, or 0.09 kg per live birth per year. At each age, women with lifetime parity of one or two live births had lower mean body weight and BMI, and a lower proportion overweight (BMI greater than 27 kg/m2), than either nulliparous women or those with three or more lifetime births. These results indicate a strong association between ageing and weight gain and a weak association between parity and both weight gain and overweight in women.

Adolescent↗

PubMed1992

Reproduction and maternal nutrition in Madura, Indonesia.

The prevalence and severity of chronic energy deficiency (CED) among women of reproductive age as well as its consequences on the newborn and the mother were assessed in a longitudinal study. More than 40% of the mothers had a Body Mass Index (BMI) less than 18.5 before pregnancy, a level below which CED is considered to exist. Weight gain during pregnancy was low, on average 6.6 kg. Taking the difference between 4 week postpartum weight and pre-pregnant weight as net weight gain during pregnancy, mothers with a BMI less than 18.5 before pregnancy gained weight while those with a higher BMI lost weight. This observation suggests that the partitioning of energy to the fetus and the mother depends on the energy reserves of the mother before pregnancy. The functional significance of BMI as an indicator of CED is illustrated by its relation with birth weight. Similarly, 4 week postpartum, weight and BMI were predictive for the weight changes in the mother in the first 12 months after delivery. The groups with the lowest values gained weight, while the heaviest mothers lost weight. In view of the negative effects of CED among women of reproductive age on the infant and the mother, maternal undernutrition should receive the same attention as malnutrition among preschool children.

Body Weight↗

PubMed1976

[A study of toxic substances in pertussis cultures].

For the purpose of studying the toxic properties of pertussis strains with different agglutination composition and to ascertain the interrelationship between the action of the toxic substances and the serological type of the strains the author used a test of the weight change in albino mice to which crude and heated (at 56 degrees C for 10 minutes) suspensions of the strains of various serological types were injected intraperitoneally. The toxic properties were checked in 17 strains. The test of the change of the animal body weight with the determination of the regression coefficient permitted to determine roughly the presence of the toxic substances in the strains; the action of the thermostable dermonecrotic toxin and thermostable endotoxin was expressed with greater constancy than that of the lymphocytosis stimulating factor. There was no interrelationship between the manifestation of the action of toxic substances in the pertussis strains and their serological type. The toxic activity peristed in the strains stored in dried condition.

Agglutination Tests↗

PubMed1977

[Relations between weight changes and various biological parameters. Results of a longitudinal epidemiological survey].

Weight changes over a three year period were measured on a group of about 1400 working men aged 46 to 52 years and related to several biological parameters (cholesterolemia, triglyceridemia, uricemia, glycemia and blood pressure). We observed: a) a slight increase in mean weight over the three year period; b) significant correlations between weight change and changes in these biological parameters. These results are compared to those found in cross sectional studies. Their implications for public health and prevention of ischemic heart disease are discussed.

Blood Glucose↗

PubMed1978

Some effects of uninfected laboratory-reared tsetses (Glossina morsitans morsitans westw.) (diptera: glossinidae) on host-rabbits.

Rabbits (Flemish giant x French lop-eared) exposed to 300 to 500 tsetses (Glossina morsitans morsitans Westw.) a day, 2 or 3 days a week, did not show significant differences from littermates receiving no exposure, with respect to weight changes, haematocrits, red and white blood cell counts or whole blood clotting times. In other rabbits, the same daily exposure, 6 days a week, resulted in sharp decreases in haematocrit levels and in some, changes in weights, but no change in citrated plasma thrombin times. Rabbit haematocrit levels correlated negatively with estimated weekly blood loss. Weights and haematocrits of most rabbits exposed to 1,200 to 1,500 flies on a single occasion were not affected. However, following heavy exposure, ears were cold and blood letting difficult, indicating the possibility of arteriolar vasoconstriction.

Animals↗

PubMed1979

Effects of social and environmental change on institutionalized mentally retarded persons: the relocation syndrome reconsidered.

The "relocation syndrome" in multiply-handicapped, institutionalized mentally retarded residents was examined in an observational study. Weight change and the initiation and duration of constructive and nonconstructive behavior was observed, as well as resident-staff interactions before and after relocation to a new living unit. The hypothesis that there would be an increase in behavior deleterious to the health of clients after relocation, when compared to two premove baseline periods of crowding, was not totally supported. Although relocation did cause significant changes in a variety of behaviors, not all were deleterious (i.e., no mortalities, weight gains). Results were discussed in terms of a social-situational model.

Adolescent↗

PubMed1979

Ingestive behavior and composition of weight change during cyproheptadine administration.

The effect of cyproheptadine on spontaneous energy intake was studied by means of an automated (liquid diet) food-dispensing apparatus in two nonobese adults confined to a metabolic ward. The experimental design included both single and double-blind periods. Throughout, the composition of daily weight change was determined by the energy-nitrogen balance method. While on cyproheptadine, both subjects exhibited increases in energy intake with the following average composition of weight gain: protein 16%, fat 14% and water 70% (first subject), and protein 5%, fat 49% and water 46% (second subject). The cyproheptadine-induced increase in energy intake was statistically significant in one of the subjects, who was at his desirable weight level at the outset. The other subject was underweight initially and tended to gain throughout the experiment, although rate of weight gain appeared to be more rapid during the periods of cyproheptadine administration. Energy output in both subjects remained fairly constant throughout. We conclude that cyproheptadine induces weight gain of 'normal' composition by stimulating increased energy intake.

Adult↗