[The neuroendocrine and neurotrophic changes in combined brain concussion and locomotor trauma (a review of the literature)].
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The results of determinations of lysosomal enzymes: mannosidase, b-galactosidase and b-glucosidase, in the cerebrospinal fluid and blood are presented in 72 patients with severe brain trauma. The determinations were carried out at different times after the trauma. The study demonstrated a significantly lower level and in a smaller degree expressed variability of enzymes in the cerebrospinal fluid in relation to blood. It seems that the level of b-glucosidase in the cerebrospinal fluid depends on the level of this enzyme in the blood, while no such evident correlation was found for the remaining enzymes.
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The purpose of the study was a trial of using the calorie pendulum test and the test of reversal of the direction of caloric nystagmus with an optokinetic stimulus for assessment of the oculovestibular response in children after brain commotion. The investigations were carried out in 30 children aged from 6 to 10 years. In both tests the movements of the eyeballs were recorded with an electronystagmograph. It was found that in this type of craniocerebral trauma a transient disturbance occurs in the functions integrating the visual and vestibular stimuli in the central nervous system. It is suggested that these tests might be useful for determination of the otoneurological status of children after brain commotion.
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