[Biochemical indices in dynamic disturbances of cerebrovascular circulation].
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
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The frequency of myocardial ischemia onsets, QT interval dispersion, homeostasis characteristics, and lipid peroxidation parameters were studied in a group of 49 patients with acute disturbance of cerebral circulation (ADCC). The Holter ECG monitoring revealed myocardial ischemia episodes in 42% of patients, and myocardial instability manifested by the QT interval variance in 82% of patients. The control group (30 patients) received standard complex therapy, while the test group (19 patients) additionally received emoxypine. The administration of emoxypine reduced the incidence of myocardial ischemia and positively influenced the QT interval variance and the main parameters of homeostasis.
One hundred and six males aged 40-59 were examined generally, neurologically and using ultrasonic dopplerography within one month following an emergency call for transitory ischemic attacks, hypertensive cerebral crises. Ultrasound signs of arterial lesions were recorded in 79.2% of the examinees. Hemodynamic disturbances occurred most frequently (50.9%). Arterial stenosis was diagnosed in 27.4% of cases. With growing number of risk factors, the incidence of major arteries lesions was on the increase.
The results of surgical treatment of 106 patients with occlusive lesions of the brachiocephalic trunk vessels have been analysed. A necessity of reorientation of the conservative approach to the treatment of patients in favour of surgical angioneurology is stressed.
The authors characterize the current stage of studies into the problem of focal cerebral ischemia under experimental and clinical conditions, formulate research priorities in the prevention, pathogenesis, diagnosis and treatment of ischemic disturbances of cerebral circulation, demonstrate the significance of new approaches to and methods of solving disputable and unsolved problems of preventive and urgent angioneurology. Based on an analysis of the latest information, the authors distinguish the most important research data on the problem of ischemic disturbances of cerebral circulation and outline prospective ways of further scientific research endeavours.
A total of 94 cases were analyzed. Transient cerebral circulatory disorders in a majority of the patients with cardiac defects were caused by intraoperative factors. Clarification of these factors and the study of clinical course of the disorders made it possible to diagnose them timely and begin the differentiated treatment.
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