PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “HORSE DISEASES”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 199 records · Page 11Linked to original sources
PubMed1981

Intestinal infarction associated with mesenteric vascular thrombotic disease in the horse.

Intestinal infarction associated with cranial mesenteric artery thrombosis, without strangulation obstruction of the intestine, was studied in 18 horses. Findings normally of value in evaluating horses with acute abdominal pain (heart rate, rectal palpation findings, gastric reflux) or classification of the degree of pain were not helpful in diagnosing the problem. Similarly, packed cell volume, plasma total protein, circulating white blood cell count, peritoneal white blood cell count, and peritoneal fluid total protein were not of value in predicting severity of the intestinal damage, location of infarction, or patient survival. In one half of the cases, peritoneal fluid color was of aid in distinguishing intestinal infarction from strangulation. Findings on gross dissection and limited histologic examination did not support the premise that thromboembolism was the major mechanism for production of infarction. In most of the horses, a thrombus or embolus was not found in the peripheral mesenteric vessels.

Animals↗
PubMed2006

Remote sensing based identification of environmental risk factors associated with West Nile disease in horses in Camargue, France.

Geographic information system and remote sensing technologies were used to identify landscape features associated with risk of West Nile virus transmission as defined by the presence of confirmed horse cases. SPOT-4 images of Camargue area were used to generate a map of landscape categories of epidemic foci and the geographic information system was employed to determine the proportion of landscape components surrounding 10 horse case sites and 17 control sites. The spatio-temporal analysis of the cases outbreak gave the best results for a spatial window of 9 km and a temporal window of 18 days. Two clusters were identified (relative risk=3.35), both in the wet area of Camargue, near the town "Les Saintes Maries de la Mer". The first one was 4 km radius, the second 9 km. The relationships between the presence of cases and proportions of landscape categories were analyzed using generalized linear model. The best model indicated that rice fields and dry bushes, wet "sansouire" and open water were the major components of the landscape that were associated with the presence of West Nile virus cases.

Animals↗
PubMedDate not supplied

Effects of orientation, intermittent rest and vehicle cleaning during transport on development of transport-related respiratory disease in horses.

The effects of various factors on the inflammatory and stress response in horses during transportation were examined in Experiments 1 and 2, carried out in April and August, respectively. In Experiment 1, three groups (G1-G3) of four Thoroughbreds were used, and in Experiment 2, two groups (G4, G5). G1 animals were loaded into lorries with their heads facing forwards (FF) and given periods of short rest (SR) (30 min for every 4 h driven). G2 horses were loaded facing rearwards (FR) and given SR. G3 horses were FF and given periods of long rest (LR) (2 h rest for every 4 h driven). G4 horses were transported FF with hay suspended in front of them and no cleaning of faeces or urine during rest stops. G5 horses were FF and given pellets instead of hay, and the lorry was cleaned and washed at each rest stop. G4 and G5 horses were rested for 1 h after every 5 h of driving. All groups were driven a distance of 1500 km, and the total journey time was 37 h for G1 and G2, 49 h for G3, and 40 h for G4 and G5. In Experiment 1, indicators of inflammatory and stress responses tended to be highest in G1, intermediate in G2 and lowest in G3. In Experiment 2 they tended to be higher in G4 than in G5. The results suggested that increasing the rest time and cleaning the interior of the vehicle during rest stops reduced transportation stress and respiratory insults, factors that may lead to respiratory disease.

Animal Husbandry↗
PubMed1986

[Endoscopic findings in horses with diseases of the upper respiratory tract].

With the aid of a flexible glassfibre endoscope, a 300 W cold light source and a special adapted camera, colour photographs of the upper respiratory tract of horses were taken. These pictures served to present especially the disease processes of the different areas of the upper respiratory tract which lead to a constriction of the lumen. These included proliferation in the nose, guttural pouch diseases and larynx diseases such as hemiplegia, subepiglottic cysts, epiglottic entrapment and rostral displacement of the plica palatopharyngica. Furthermore endoscopic findings of changes in the soft palate and in the recessus pharyngicus were shown.

Animals↗
PubMed1992

Periodic paralysis in quarter horses: a sodium channel mutation disseminated by selective breeding.

We recently reported on a linkage study within a Quarter Horse lineage segregating hyperkalaemic periodic paralysis (HYPP), an autosomal dominant condition showing potassium-induced attacks of skeletal muscle paralysis. HYPP co-segregated with the equine adult skeletal muscle sodium channel alpha subunit gene, the same gene that causes human HYPP. We now describe the Phe to Leu mutation in transmembrane domain IVS3 which courses the horse disease. This represents the first application of molecular genetics to an important horse disease, and the data will provide an opportunity for control or eradication of this condition.

Amino Acid Sequence↗
PubMed1983

Chronic obstructive pulmonary disease in the horse. 1: Nature of the disease.

The aetiology, pathophysiological changes, pathology and clinical signs of the disease as presently understood are discussed. The condition appears to be a hypersensitivity of the respiratory system in some horses to poor quality hay and straw. Micropolyspora faeni is the chief agent identified in the northern part of the United Kingdom. In other locations, the chief agent is probably different. The principal changes are spasm of the airways and bronchiolitis of the small airways. Onset may be acute or insidious. The chief clinical signs are well known but the disease process is reversible if the source of the antigen is removed. In early cases, determination of increased maximum intrathoracic pressure changes and co-existent subnormal arterial oxygen pressure are the best objective confirmation of diagnosis. The same measurements may be made on asymptomatic horses if they have been challenged 4 to 5 h earlier by inhalation of the appropriate antigen, or even exposed to poor quality hay or straw. Other methods available to the clinician are discussed.

Allergens↗
PubMed1998

Monitoring and detection of acute viral respiratory tract disease in horses.

OBJECTIVE: To develop a system to monitor and detect acute infections of the upper respiratory tract (i.e., nares, nasopharynx, and pharynx) in horses and to assess the association among specific viral infections, risk factors, and clinical signs of disease. DESIGN: Prospective study. ANIMALS: 151 horses with clinical signs of acute infectious upper respiratory tract disease (IURD) from 56 premises in Colorado. PROCEDURE: Health management data, blood samples, and nasal or nasopharyngeal swab samples were obtained for 151 horses with clinical signs of acute IURD. Of these horses, 112 had an additional blood sample obtained during convalescence and were considered to have complete sample sets. Samples were tested for evidence of respiratory tract infection by use of ELISA, virus isolation, and serologic testing of paired serum samples. RESULTS: Viral infections were identified in 65 horses with complete sample sets; influenza virus infection was identified in 43 horses, equine herpesvirus (EHV) infection in 18, and mixed influenza virus and EHV infections in 4. On 14 premises, samples were obtained from more than 1 affected horse. Viral infections were identified in horses on 11 of 14 premises. Equine herpesviruses were isolated from 10 horses. A relationship was not found between vaccination history and identification of EHV or influenza virus infections. An infection with EHV was less likely to be identified in horses with initial (acute) antibody titers > 1:16 to EHV. CLINICAL IMPLICATIONS: Influenza virus (specifically, A/equine/2) was the most common virus associated with acute IURD. Use of multiple diagnostic tests and obtaining samples from more than 1 horse in an outbreak may improve detection of viral infections.

Acute Disease↗
PubMed1980

Correlation of dermal-epidermal laminar lesions of equine hoof with various disease conditions.

Dermal and epidermal laminar lesions were correlated with acute intestinal, primary hepatic, septicemic, chronic laminar, and acute laminar diseases. Horses with acute intestinal disease had edema in the secondary dermal laminae. Those with hepatic disease had increased keratinization of the secondary epidermal laminae. Septicemia caused increased keratin formation in the primary and secondary epidermal laminae. Chronic laminitis caused architectural changes of the epidermal laminae characterized by hyperplasia and keratin formation of the basal epidermal layer. Horses with acute laminitis had epidermal necrosis, especially with peracute laminitis. Various insults to the epidermal laminae led to epithelial hyperplasia of the secondary epidermis with ventral deviation of the third phalanx.

Animals↗
PubMed1994

Evaluation of the thoraco-laryngeal reflex ('slap test') as an aid to the diagnosis of cervical spinal cord and brainstem disease in horses.

A study was conducted over a 12 month period to assess the specificity and sensitivity of the 'slap test', using endoscopic evaluation, in the detection of cervical spinal cord and caudal brainstem lesions in horses. Fifteen ataxic horses were subjected to the 'slap test' and subsequently examined post mortem. Twelve out of the 15 had histopathological lesions consistent with their clinical signs. Thirteen horses with no history of neurological dysfunction and no histopathological evidence of cervical spinal cord or brainstem disease were used as controls. The laryngeal adductory responses exhibited by all horses were filmed and later scored independently by 3 assessors. The proportion of animals diagnosed with cervical spinal cord and/or brainstem disease, defined by histopathological criteria, was found to be statistically similar to the proportion with abnormal 'slap test' responses, using the McNemar chi-Square test. Despite statistical significance between proportions, sensitivity of the 'slap test' was low, 50% for the left side on both days and 58% for the right side. Specificity was higher, 69% (Day 1) and 75% (Day 2) for the left side and 75% (Day 1) and 69% (Day 2) for the right side. In contrast to this, conventional neurological examination was found to be 100% sensitive and 81% specific in the detection of lesions of histopathological significance in the cervical spinal cord/caudal brainstem. Agreement between scores for the 'slap test' from the same assessor on different days was good, with values for kappa of 0.59 to 0.85. In contrast, agreement between assessors on the 'slap test' score was poor, with kappa 0.35.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1986

Diurnal variation of dynamic compliance, resistance and viscous work of breathing in normal horses and horses with lung disorders.

Dynamic compliance, airway resistance, viscous work and respiratory frequency were measured at intervals in horses over 12 h periods. Variation, daily averages and circadian patterns were recorded. Examinations were performed on 24 horses. They were divided into three groups: Normal horses, horses with chronic latent bronchitis and horses with manifest chronic obstructive pulmonary disease (COPD). Significant differences were found between the daily averages and the fluctuations when the normal group and the COPD group were compared. In most cases differences between all three groups were significant. A significant circadian rhythm for airway resistance was detected in diseased horses. It was also established that single measurements give an incomplete picture of lung function. As has been established in humans, analysis of fluctuations in respiratory mechanics may be of diagnostic value. The above results should be taken into account particularly in trials with bronchodilators in horses with COPD.

Airway Resistance↗
PubMed1998

Onychomycosis in white line disease in horses: pathology, mycology and clinical features.

This paper describes onychomycosis in horses and reports the pathological findings, associated fungi and incidence of concurrent white line disease. In addition to these observations, relevance between post mortem and clinical findings of onychomycosis are discussed in 3 necropsied horses. Samples were collected from 100 hooves from a total of 51 Thoroughbreds suffering from white line disease. Of these, 15 hooves from 13 horses were also complicated with severe hoof wall fissure formation. Preparations from the same samples were used both for histopathology and for culture to identify the associated fungi. Onychomycosis was diagnosed when it could be confirmed histologically. Fungal identification was based on morphological characteristics in culture and the associated fungi were determined by comparison with culture morphology. As a result, 10 samples collected from horses were diagnosed as suffering from onychomycosis. Seven of these showed complicating severe inner hoof wall fissures and the soil fungus Scedosporium apiospermum or the teleomorph of this fungus, i.e., Pseudallescheria boydii, was isolated. The fungus was found to be ubiquitous in the fissure cavities, the terminal horn of the white line and the terminal horn-like laminae of the metaplastic white line-like tissue. It can be concluded that onychomycosis frequently causes white line disease and/or makes it worse. Associated with deterioration of the submural condition, the main associated fungus for onychomycosis in this series, was Genus Scedosporium and the most susceptible region was the terminal horn of the hypertrophied white line and/or the terminal horn-like laminae of the metaplastic white line-like tissue.

Animals↗