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At least 199 records · Page 11Linked to original sources
PubMed1988

Theoretical models of cyst formation and growth.

Although the formation of fluid-filled, epithelial-lined cysts is a common event in a variety of tissues, the mechanisms involved are not well understood. Discussed here are means by which those mechanisms might be elucidated. In general, there are too few data available for complete analysis of in vivo disease processes. It can be suggested only that epithelial proliferation and basement membrane growth are probably absolute requirements. Whether the forces for fluid accumulation precede or follow the stimuli for cell growth cannot be stated with certainty. On the other hand, in certain in vitro model systems the forces required to keep cyst cavities filled with fluid may be so small that cell growth, rather than fluid accumulation, seems the more likely primary event.

Animals↗
PubMed1969

A theoretical model of the dynamics of an Anopheles gambiae population under challenge with eggs giving rise to sterile males.

An explanation is given of the probable effects of seeding a breeding place of Anopheles gambiae with hybrid eggs that produce almost exclusively sterile males. For the calculations, the dynamics of an A. gambiae population in a single breeding place have been simulated in a computer programme.General considerations and implications are discussed with reference to practical applications, and the conclusion is reached that it will be feasible to eradicate the species from any breeding place only if the number of factory-produced eggs distributed daily bears a known, optimal relationship to the numbers deposited daily on the site.The period of treatment, if the first-day ratio of normal: factory-produced eggs is 1: 1, was estimated to be in the region of 9 weeks. Several runs of the computer have been condensed in a graph which might be used in the early evaluation of progress in the field.

Animals↗