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At least 199 records · Page 11Linked to original sources
PubMed1977

Pasteurella multocida infection of urinary tract in patient with ileal loop.

Pasteurella multocida infection in the ileal loop and in the pelvis of a hydronephrotic kidney of a patient whose other kidney had been removed at age six months was documented by the repeated isolation of this patthogen. Two episodes occurred, the first terminated after a dose of gentamicin and the other without chemotherapy. Since the patient prior to infection was in severe renal failure necessitating hemodialysis, the effect of this infection on renal function could not be ascertained. The probable source was a cat present in the household.

Adolescent↗
PubMed2001

Ultrastructural pathology of nasal and tracheal mucosa of rabbits experimentally infected with Pasteurella multocida serotype D:1.

Sixteen 8- to 9-week-old Pasteurella multocida-free New Zealand White rabbits were divided into two equal groups. The first group was inoculated intranasally with P multocida serotype D:1 strain and the second group that was inoculated with phosphate-buffered saline (PBS) only was used as a control group. Pasteurella multocida was isolated from the nasal cavity of all infected rabbits in group 1 and from tracheal swabs of seven rabbits in this group. Four rabbits in group 1 died with clinical signs of septicaemia, two rabbits had mucopurulent nasal discharge and pneumonic lesions and the other two did not show any clinical signs or gross lesions. The ultrastructural changes detected were deciliation or clumping of cilia of ciliated epithelium, cellular swelling, vacuolation and sloughing. The subepithelial capillaries showed congestion, intravascular fibrin deposition, platelets aggregation and endothelial injury. Pasteurella multocida was observed attached to the injured endothelial cells. Heterophils, mast cells, vacuolated monocytes and macrophages infiltrated the lamina propria and between the degenerated epithelial cells.

Animals↗
PubMed1997

Pasteurella multocida infection of a total hip arthroplasty following cat scratch.

Pasteurella multocida is a well recognized cause of sepsis following animal contact particularly bites and scratches. Spread to prosthetic joints may occur particularly in immunocompromised patients. Immunocompromised patients with prosthetic joints should be warned that animals are potential sources of serious infection and urgent medical advice should be sought if bitten or scratched.

Animals↗
PubMed1992

Polypeptides associated with Pasteurella multocida infection in rabbits.

Polypeptides from whole cell preparations of Pasteurella multocida serotypes A:12 and A:3 were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and transferred to nitrocellulose paper. Antigens were detected by immunoblot analysis, using sera from 3 groups of rabbits. Sera were obtained from rabbits inoculated intranasally with P multocida serotype A:12 or A:3, from rabbits maintained in a rabbitry with enzootic P multocida A:12 infection, and from rabbits maintained in a rabbitry with enzootic P multocida A:3 infection. Immunoblot analyses of pre- and postinoculation sera from experimentally infected rabbits, using serotype A:12 antigen, revealed 3 polypeptides with approximate molecular mass of 28, 30, and 37 kDa that consistently detected antibodies after P multocida-induced infection. Sera from rabbits naturally infected with either serotype, tested against serotype A:12 and A:3 antigens, detected the same polypeptides in both serotypes. Thus, immunologic reactivity to these polypeptides may be useful for serologic detection of P multocida infection.

Animals↗
PubMed1984

Pasteurella multocida urinary tract infection.

Most Pasteurella multocida infections in humans have been associated with animal bites or scratches. While a variety of infections involving P multocida, unassociated with animal trauma, have been described, infections of the urinary tract are rare. We studied a case in which P multocida was isolated from the urine of a woman with advanced uterine cervical cancer. In most of the cases in which P multocida has been isolated from urine, the patients have had anatomic defects of the urinary tract, as well as an underlying chronic illness. These host-related characteristics appear to be important in the pathogenesis of P multocida urinary tract infection.

Adult↗
PubMed1983

Protection against Pasteurella pneumotropica during infection with Angiostrongylus cantonensis.

Lung infections of specific-pathogen-free rats were studied to determine cross-immunity between infections with Pasteurella pneumotropica and Angiostrongylus cantonensis. Rats were found to have differences in mortality due to pneumonic infections with P pneumotropica and A cantonensis and to coinfections of P pneumotropica and A cantonensis. Single infections of P pneumotropica were not dosage-dependent in their lethality for specific-pathogen-free rats. The mortality of coinfection with P pneumotropica and A cantonensis was significantly lower than that of a monoinfection with P pneumotropica, demonstrating a cross-protective phenomenon.

Angiostrongylus↗
PubMed1995

Necrotizing fasciitis due to Pasteurella multocida infection.

Necrotizing fasciitis is a potentially fatal clinical disease caused by infection with various bacteria in addition to streptococci, which are common causative agents. We report on a rare case of this disease in association with Pasteurella multocida infection. A 58-year-old man had systemic features of shock after a 15-hour history of a painful swelling on the right lower leg. The swelling led to skin blistering and necrosis from which P. multocida was isolated. Those lesions progressed rapidly. The patient also had a history of chronic liver injury as described in previous reports.

Blister↗
PubMed2003

Postoperative wound infection with Pasteurella multocida from a pet cat.

We summarize an unusual postoperative wound infection that was caused by Pasteurella multocida from a house cat licking the incision in an obese gynecologic oncology patient. A 48-year-old morbidly obese woman had a wound abscess 6 weeks after hysterectomy and panniculectomy for a International Federation of Gynecology and Obstetrics stage IA grade 1 endometrial cancer. P multocida was cultured from the abscess and the patient was treated with drainage and intravenous antibiotics. Further history revealed that her house cat had licked the wound. P multocida wound infection is a potential complication for people with dog or cat contact postoperatively. Penicillin G is the antibiotic of choice for treatment.

Abscess↗
PubMed1984

Promotion of Pasteurella haemolytica infection in mice by iron.

Mice given 60 micrograms iron, as aqueous ferric ammonium citrate, intravenously were more susceptible than untreated controls to intraperitoneal infection with T serotypes of Pasteurella haemolytica as shown by significant reductions in LD50 values. Iron injection has advantages over administration of bacteria suspended in mucin for studies of P haemolytica infection in mice.

Animals↗
PubMed2006

Pasteurella multocida infection of a total knee arthroplasty after a "dog lick".

The patient we report here underwent a total knee arthroplasty (TKA) which got infected with P. multocida after her dog had licked a small wound at the third toe of the same foot. Despite a correct treatment comprising synovectomy and cleansing, and an active antibiotic treatment for 3 months, the patient was readmitted for persistent infection of the same knee 2 weeks after the end of the antibiotic treatment. Sampling during surgery allowed for the growth of a P. multocida isolate proven by a molecular method to be identical to the previously isolated strain. This recurrent P. multocida infection was treated by a two-step change of the TKA comprising a 2-month period of antibiotic treatment between the two surgical interventions.

Aged↗
PubMed1994

The role of eicosanoids in the chemotactic response to Pasteurella haemolytica infection.

The chemotactic role of eicosanoids in the pathogenesis of Pasteurella haemolytica infection was studied, using a tissue chamber infection model and pharmacological inhibitors of eicosanoid synthesis. Tissue chambers were implanted subcutaneously in 12 calves allotted to three treatment groups of equal size. At 45 days after implantation, calves received saline, dexamethasone, or phenylbutazone treatments, and tissue chambers in all animals were then inoculated with P. haemolytica. Chamber fluid samples were collected before inoculation and at 2, 6, 18, 40, and 90 h after inoculation. Bacterial counts, total leukocyte counts, pH and albumin concentrations in chamber fluids were determined using standard bacteriological and clinical pathological methods. Concentrations of eicosanoids and activity of interleukin-1 (IL-1) were measured by radioimmunoassay and a helper T cell bioassay, respectively. Concentrations of leukotriene B4 (LTB4), thromboxane B2 (TXB2), 6-keto-prostaglandin F1 alpha (PGF1 alpha) and prostaglandin E2 (PGE2) increased markedly after inoculation. An inhibitory effect of dexamethasone on both LTB4 production and neutrophil influx, together with the temporal relationship between these two events, suggested that LTB4 served as a chemo-attractant. Activity-time profiles for IL-1 in chamber fluids were similar to those of the eicosanoids. Phenylbutazone and dexamethasone reduced the severity of the inflammatory responses as measured by lower concentrations of albumin and higher pH in treated versus control chamber fluids. The results of this study suggest that eicosanoid inflammatory mediators play an important chemotactic role in the pathogenesis of P. haemolytica infection.

Animals↗
PubMedDate not supplied

Ophthalmia in turkeys infected with Pasteurella multocida.

Blepharoconjunctivitis and hypopyon were observed in eyes of turkeys infected during 2 epornitics of fowl cholera. Blepharoconjunctivitis, hypopyon, anterior synechiae, and panophthalmitis were observed sporadically in turkeys experimentally exposed to Pasteurella multocida via drinking water. P. multocida was isolated from these lesions.

Animals↗
PubMed1996

Detection of toxigenic Pasteurella multocida infections in swine herds by assaying antibodies in sow colostrum.

Toxigenic Pasteurella multocida is the causative agent of progressive atrophic rhinitis (PAR), a serious respiratory infection of swine. Diagnosis of the disease has hitherto been based on clinical signs, pathologic findings, and subsequent isolation of the agent. The best Finnish pig breeding herds participating in the Finnish Pig Health Scheme have been surveyed for PAR since 1963, and the disease has been eradicated from these herds. In this study, a total of 5,650 colostrum samples from 188 Finnish Pig Health Scheme herds were analyzed with a new serologic screening method: an enzyme-linked immunosorbent assay (ELISA) able to detect antibodies to the toxin of P. multocida (PMT). Although the herds had been continuously controlled for PAR, 1 herd with PMT antibodies was found. The positive reactions in the ELISA were confirmed by isolating the causative organism. The origin of the infection also appeared to be obvious. The serologic ELISA is a suitable method for the detection and screening of toxigenic P. multocida-infected pig herds.

Animals↗