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PubMedDate not supplied

Is osteoporosis a pediatric disease? Peak bone mass attainment in the adolescent female.

Osteoporosis in the elderly woman is determined by the amount of peak bone mass in adolescence, the premenopausal maintenance of such peak bone mass, and the rate of postmenopausal bone mass loss. The majority of research efforts in the past have been directed at defining the pathogenesis and treatment of postmenopausal osteoporotic bone loss. A comparatively new, and potentially fertile, area of research deals with factors responsible for attaining and augmenting peak bone mass in the adolescent female. Determinants of peak bone mass include genetic, nutritional, weight loading (exercise), and environmental factors. Nutritional factors, especially calcium, are potentially most amenable to therapeutic manipulation. Current data suggest that calcium deficiency exists in the adolescent female; and, although the current data are preliminary and not conclusive, they suggest that increasing calcium intake may be of value in increasing peak bone mass. However, assurance of compliance in the teenage female population in increasing calcium intake is difficult; relating a disease of the elderly, such as osteoporosis, to a teenage female population, a population that may experience the disease 40-50 years later, is frequently frustrating. Nevertheless, increased attention must be directed toward increasing calcium intake in this population of females. The amount of bone mass in adolescence may determine the amount of bone mass postmenopausally; a high or low peak bone mass may, therefore, contribute to protection against, or risk of, subsequent fracture. The ultimate target population for osteoporosis prophylaxis may indeed be the young, rather than the elderly, female.

Adolescent↗
PubMedDate not supplied

The significance of increased echogenicity in the detection and differentiation of pediatric disease.

Increased renal echogenicity, by ultrasonography, is seen in various pathological conditions. Correlation of renal size with the pattern and distribution of the increased echogenicity, and the patient's age and clinical data will limit the differential diagnosis and suggest the appropriate radiographic follow-up studies, obviating the need for unnecessary procedures.

Burkitt Lymphoma↗
PubMed1987

[Varicocele testis--a pediatric disease?].

The inquiries and evidences demonstrated deal with the consequences of the varicocele disease which had remained unattended in childhood. They are based on representative collective statistics and examinations of the own patients. The parameters density of spermatozoa, motility of spermatozoa, paternity, volume of the testes and histomorphology of the testes refer to the diminution of the fertility beyond adolescence. Operatively treated children have a more favourable prognosis of fertility.

Adolescent↗