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At least 199 records · Page 11Linked to original sources

Conservative treatment of liver hematoma in the postpartum period. A report of two cases.

Two pregnant women at term had antenatal symptoms of impending preeclampsia (thrombocytopenia, liver dysfunction) and developed clinical signs of a leaking subcapsular liver hematoma in the immediate postpartum period. They were managed conservatively, with blood transfusions and ultrasonic computerized tomographic monitoring of the hematoma. Both did well, and their hospital stays were brief. These cases suggest that immediate celiotomy may not always be necessary for suspected liver hematoma associated with preeclampsia.

Adult↗

Acute lupus pneumonitis in the postpartum period: a case history and review of the literature.

A patient is described who developed acute lupus pneumonitis in the puerperium. The difficulty in arriving at this diagnosis and the confusion with infectious etiologies of postpartum illness is described. Other manifestations of pulmonary disease in systemic lupus erythematosis are discussed, and the literature regarding acute lupus pneumonitis in the postpartum period is reviewed.

Acute Disease↗

Serum and saliva cortisol relations in adolescents during pregnancy and the early postpartum period.

The purpose of this investigation was to examine: (1) relations between serum and saliva cortisol in adolescents in pregnancy and early postpartum and (2) short-term consistency of serum and saliva cortisol across three samples, 20 minutes apart, as well as the long-term consistency from pregnancy to early postpartum. Pregnant adolescents (n = 40), ages 14 to 19 years, were enrolled in this study. Subjects were seen at 20 weeks gestation or earlier (T1), 34-36 weeks gestation (T2), and 2-3 weeks postpartum (T3). Blood samples were drawn at T1 and T3, at 0, 20, and 40 minutes. Saliva samples were collected across the same 40-minute period at T1, T2, and T3. Spearman rho (rs) correlation coefficients between serum and saliva ranged from 0.72 to 0.77 (T1), and 0.42 to 0.60 (T3) (p < or = 0.05). Short-term consistency between serum cortisol samples was 0.86-0.97 at T1 and 0.60-0.82 at T3. Short-term consistency for saliva cortisol samples was 0.70-0.96 at T1, 0.91-0.95 at T2, and 0.64-0.89 at T3. Long-term consistency (T1 to T3) for serum and saliva cortisol was low. Individual differences as well as dramatic changes in the endocrine environment in pregnancy and the early postpartum period may explain the more moderate serum-saliva correlations in the postpartum period.

Adolescent↗

[A combined reflex method in the treatment of suppurative-infectious diseases in the postpartum period].

The purpose of this study was to develop an effective pathogenetically validated method for the treatment of puerperants with pyoseptic diseases, making use of reflex therapy, and clinical assessment of this method. The study has involved 190 puerperants, in 50 of them the postpartum period ran a normal course and the rest 140 developed pyoseptic complications. Case histories were analyzed, clinical and laboratory tests (blood proteins, Mancini's test for immunoglobulins, Dorofeichuk's blood plasma lysozyme test) were carried out. Vegetative regulation was studied with the use of a vegetative test kit. A method for reflex therapy of the detected disorders of the vegetative regulation associated with puerperal pyoseptic diseases has been developed, resulting in strengthening of the defense potential of the body. Clinical assessment of the method has confirmed its high efficacy.

Female↗

Female genital mutilation (FGM) management during pregnancy, childbirth and the postpartum period.

Female genital mutilation (FGM) is a traditional practice with serious health consequences to women that is still practiced in 28 countries with approximately 2 million girls exposed to the practice annually. The complications of FGM cause suffering to the woman all her life. Pregnancy, childbirth and the postpartum period are particularly important as there is increased risk of mortality and morbidity from FGM complications. Although the overall strategy should be to eliminate the practice completely, the healthcare providers and policy makers in the meantime should not only be aware but also well trained in the management of FGM complications to decrease the risk of mortality and serious morbidity.

Circumcision, Female↗

Postpartum period: a risk factor for neuroleptic malignant syndrome.

Neuroleptic malignant syndrome (NMS) occurred in four postpartum patients treated with various psychotropic medications including depot-neuroleptics over a 5-year period. All four patients had the onset of NMS in the first few weeks of the postpartum period. Whether or not there is an increased risk for the development of NMS in the puerperium period is discussed.

Adult↗

Maternal prolactin concentrations and lactational behaviour in the early postpartum period in women with lactational amenorrhoea.

OBJECTIVE: To compare early postpartum differences in maternal prolactin concentrations and lactational behaviour between women who have short and long periods of lactational amenorrhoea. METHODS: Healthy lactating women resuming regular menstruation before 24 weeks [short amenorrhoea (SA) group; n = 15], and at or after 24 weeks [long amenorrhoea (LA) group; n = 15] postpartum were studied from 4 to 12 weeks postpartum. Infant feeding pattern and maternal plasma prolactin concentrations were compared between the two groups using repeated measures ANOVA. RESULTS: Breastfeeds/24 h were significantly higher and other feeds/24 h were significantly lower (p < 0.01) at 12 weeks postpartum in the LA group when expressed as a percentage of all feeds. Number of breastfeeds (total/24 h and night) significantly decreased and the number of other feeds significantly increased (p < 0.05 to 0 < 0.001) with time in both groups. Prolactin concentrations (basal, suckling stimulated and increment) were higher in the LA group, but consistent significant differences were observed mainly in the increment (p < 0.05 to p < 0.001). Prolactin concentrations significantly (p < 0.01 to < 0.001) decreased with time postpartum in the SA group, but not in the LA group. CONCLUSIONS: Women with longer periods of lactational amenorrhoea maintain higher prolactin concentrations than those with shorter periods of lactational amenorrhoea during the early postpartum period, even when the breastfeeding frequency is reduced. This could be explained by a greater sensitivity of the pituitary lactotrophe to the suckling stimulus in women who have longer periods of lactational amenorrhoea.

Adult↗

Comparison of two positive reinforcing stimuli: pups and cocaine throughout the postpartum period.

This set of experiments investigated the appetitive or motivational processes underlying the performance of maternal behavior. The place preference paradigm was adapted to simultaneously investigate the reinforcing properties of cocaine and pups for maternal, lactating dams. These modifications allowed the authors to assess which stimulus, either a 10 mg/kg s.c. injection of cocaine or 3 pups, had the strongest reinforcing value. At Postpartum Days 10 and 16, the dams preferred the cocaine cue-associated chamber, whereas the dams tested at Postpartum Day 8 preferred the pup cue-associated chamber. Overall, the data revealed an interaction between the postpartum period at testing and the exhibited preference for cocaine or pups. Further testing will investigate the neural circuitry underlying the appetitive processes of each stimulus.

Animals↗

Course of mood and anxiety disorders during pregnancy and the postpartum period.

Because the onset of mood and anxiety disorders often occurs during the childbearing years, many women may be taking psychotropic medications for these disorders when they conceive. These medications easily diffuse across the placenta, and their impact on the fetus is of concern. But discontinuation may lead to relapse, in which case psychiatric symptoms may affect the fetus. Thoughtful treatment planning presents a dilemma to the clinician. Limited data suggest heightened vulnerability to relapse of mood and anxiety disorders in women during the postpartum period. Pregnancy appears to exacerbate symptoms of obsessive-compulsive disorder, while panic disorder patients may remain well after discontinuing medication. Future studies should address the prevalence and relapse rates of mood and anxiety disorders, particularly after medication discontinuation, among pregnant women.

Anxiety Disorders↗

Vaginal colonization or infection with Candida albicans in human immunodeficiency virus-infected women during pregnancy and during the postpartum period. Women and Infants Transmission Study Group.

We evaluated the relationship between immunologic status and vaginal colonization or infection with Candida albicans for 605 women enrolled in a multicenter, prospective cohort study of mother-to-infant transmission of human immunodeficiency virus type 1 (HIV-1). A low CD4+ lymphocyte level (< 14% vs. > or = 14%, which corresponds to an absolute count of approximately 200 x 10(6)/L) was associated with a two- to fivefold increased likelihood of vaginal colonization (odds ratio [OR], 2.28; 95% confidence interval [CI], 1.01-5.19) and vaginal candidiasis (OR, 3.08; 95% CI, 1.21-7.71) during pregnancy and during the postpartum period (OR, 2.98; 95% CI, 1.51-5.88 and OR, 5.45; 95% CI, 1.73-16.6, respectively). These associations persisted in multivariate logistic regression analyses. No associations with CD8+ lymphocyte levels or CD8+ CD38+ or other lymphocyte subset levels were found after adjustment for CD4+ cell level and other covariates. However, postpartum (but not antepartum) antibiotic use and pregnancy were also associated with vaginal colonization and candidiasis (P < or = .001 for each). Vaginal candidiasis was not associated with an increased risk of mother-to-infant transmission of HIV-1; however, a related, more inclusive variable, clinical vaginitis or vaginosis of any etiology at the last antepartum visit, was associated with mother-to-infant transmission (OR, 1.92; 95% CI, 1.07-3.43). These findings emphasize the complex, multifactorial nature of vaginal candidiasis and highlight the need for safe and effective treatment and prevention strategies for women with advanced HIV infection.

Adult↗

Electrolyte composition of human breast milk beyond the early postpartum period.

The electrolyte composition of breast milk beyond 6 months postpartum has not been extensively examined, particularly chloride concentrations. A total of 140 samples of breast milk from 30 breast-feeding mothers were collected and analyzed. Mean mother's values +/- standard error of sodium (141 +/- 17 mg/L), potassium (480 +/- 11 mg/L), and chloride (452 +/- 32 mg/L) were found to be stable after 4 months postpartum until weaning commenced. Considerable variability was found for each constituent, equally divided between intra-individual and inter-individual for chloride and potassium, and predominantly intra-individual for sodium and lactose. In light of reported nutritional deficiency states involving electrolytes in exclusively breast-fed infants, it is possible that the variability of breast milk electrolyte concentrations may adversely affect infant nutrition in selected cases of older exclusively breast-fed infants.

Chlorides↗

Cardiac tamponade in the early postpartum period as the presenting and predominant manifestation of systemic lupus erythematosus.

Pericarditis is a common manifestation of systemic lupus erythematosus (SLE), however, tamponade seems to be extremely rare. A review of the English literature revealed 12 such cases and in 5 the tamponade was the presenting symptom of the disease. We describe an additional patient. She developed pericardial tamponade one week after delivery of a healthy child, and subsequently was diagnosed to have SLE. The effect of pregnancy and the postpartum period on SLE is discussed.

Adult↗

Seronegative systemic lupus erythematosus: etiology of nephrotic syndrome and acute renal failure in early postpartum period.

Systemic lupus erythematosus (SLE) is an autoimmune syndrome that occurs most commonly in women during their reproductive years. Nephritis is known to be one of the most serious complications of SLE. Lupus nephropathy is frequently associated with ANA and anti-dsDNA antibodies. Rarely, serological markers may be initially absent, and in many cases, they become positive after sometime. We present a 28-year old, otherwise healthy female who admitted to our clinic with edema, hypertension, proteinuria and acute renal failure following her fourth delivery. Serum immunological markers were negative and renal biopsy showed histopathological changes consistent with systemic lupus erythematosus as the etiology of nephrotic syndrome. A dramatic therapeutic response was achieved by pulse steroid and cyclophosphamide treatment following oral steroid therapy. In women with new onset nephrotic syndrome or renal function deterioration in postpartum period, even if the patient is asymptomatic or seronegative, it is crucial to exclude SLE for a rapid diagnosis and prompt treatment in the case of lupus nephritis. Renal biopsy is of diagnostic importance in such cases in which there is no other clinical, biochemical and serological evidence of the disease.

Acute Kidney Injury↗