Conditions for high resolution radioisotope scanning.
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A 22-year-old man with burning pain in the lower abdomen and rectal bleeding had a sodium pertechnetate Tc 99m scan. The scan showed an area of uptake in the right lower quadrant which at operation was found to be a Meckel's diverticulum. The ability of ectopic gastric mucosa within a Meckel's diverticulum to concentrate sodium pertechnetate Tc 99 m allows for this noninvasive diagnosis of some types of rectal bleeding, especially when the cause has escaped detection by conventional endoscopic and barium contrast examinations.
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Quantitative thyroid scanning using low doses of 99mTc sodium pertechnetate (1.85-3.7 MBq) was performed in 38 cases of congenital hypothyroidism. Of these 38 cases, 29 were scanned at 14 +/- 6 days old, and 9 at 1 year old. The scans show the full range of gland anatomy from athyreotic to normal. All morphologically normal scans had grossly increased uptakes of 99mTc. The incidence of the various thyroid anatomies was different in each age group. The average radiation dose to the thyroid was 2.29 mGy, with at least 70% of patients receiving a dose of 3.0 mGy or less. Such low doses of 99mTc should allow further scanning in later life. Neonatal thyroid scanning reveals the aetiology of congenital hypothyroidism and enables the clinician to assess the short- and long-term needs of the child.
Sixteen outpatients with rheumatoid arthritis took part in a placebo controlled double-blind crossover study. In addition to conventional measurements, a radioactive index was measured using a gamma camera that indicated a radioactive count over the measured joints and a comparable area of normal adjacent bone. This index showed poor correlation with other conventional measurements of change in the clinical trial.
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