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Urticaria from Trichomonas vaginalis infection.

We report the case of a 32-year-old woman who had pruritic urticarial skin lesions associated with episodes of arthralgia. The first site affected by the eruption was the inside surface of the thighs; the patient also reported the presence of leukorrhea. The woman had previously been treated with H1 antagonist with moderate and transitory results; skin lesions reappeared just after the interruption of the treatment. Her biochemical data showed increased levels of erythrocyte sedimentation rate, blood eosinophilia and hypocomplementemia. Antinuclear antibodies, rheumatoid factor, cryoglobulins and serological diagnosis for hepatitis or mononucleosis viruses resulted negative. Considering the initial site of the cutaneous features and the presence of leukorrhea, we requested a vaginal smear and a culture of the cervical secretion, which revealed the presence of a Trichomonas infection. Furthermore, the SDS-PAGE revealed the presence of a molecular mass of 230,000 Da (230-kDa) in the serum, which indicated a Trichomonas surface protein. The following treatment with oral metronidazole caused the eradication of the Trichomonas infection after 3 weeks and subsequently the resolution of the urticarial clinical features. We wish to underline that in the presence of a case of urticaria vasculitis syndrome which seems to be without cause, it is important to investigate every diagnostic suspicion scrupulously.

Adult↗

Trichomonas vaginalis infection of the median raphe of the penis.

A case of trichomonas vaginalis infection involving the median raphe of the penis is presented. The infection was contracted after sexual exposure. The patient had no urethral discharge but had a penile swelling tht discharged pus. Microscopic examination and culture of the discharge showed the presence of T. vaginalis. Treatment with metronidazole (250 mg thrice daly for seven days) eradicated the infection, but the swelling remained and a cyst was excised. One month after the surgical procedure, the patient was clinically normal and cured of the infection.

Adult↗

Observations of Trichomonas vaginalis infections at the University Teaching Hospital in Calabar, Nigeria.

The pattern of Trichomonas vaginalis infections at the Outpatient Clinic of the University Teaching Hospital in Calabar, Nigeria was determined for the two-year period (January 1981 - December 1982). Of the 5520 patients examined in 1981, T. vaginalis was found in 10 males (0.11%) and 57 females (1.03%). Of the 2511 patients examined in 1982, the parasite was found in 27 males (1.07%) and 31 females (1.20%). A few prepubertal cases were observed. The increasing significance of T. vaginalis as a public health problem in this area is discussed.

Adolescent↗