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At least 199 records · Page 11Linked to original sources
PubMed2004

[Weil's disease: a severe case with respiratory insufficiency].

In the patient case (man, age 25) with suspected leptospirosis, indication for polymerase chain reaction (PCR) are supposed and procedures suitable for taking biological material are recommended. In the presented case of leptospirosis, serious conditions were accompanied by high fever, chills, hepatorenal failure, meningitis, pneumonia, increased bleeding time and further symptoms are described. Introduction of the molecular biological methods (PCR) enables to determine leptospiroses diagnosis even in the early phase of the disease, when the antibodies are not yet formed. Detection of DNA pathogenic leptospires in the PCR method is completed with serological examination by microagglutination-lysis (MAL) method for determination of the corresponding serovar that is important from therapeutic and epidemiological reasons.

Adult↗
PubMed1978

Bilateral neuralgic amyotrophy complicating Weil's disease.

The case of a patient with leptospirosis (treated with trimethoprim) with late neurological complications manifesting as a bilateral plexus syndrome is described. The probable reasons for the continued weakness, in this patient, of the muscles supplied by the anterior interosseus nerve, despite improvement in the proximal muscles, are briefly discussed.

Brachial Plexus Neuritis↗
PubMedDate not supplied

[Weil's disease: report on 5 cases in the valley of Mexico].

Leptospirosis, an acute generalized infection transmitted to humans from wild or domestic mammals, is rarely found in urban areas. We report here our experience with five cases of confirmed leptospirosis in the urban area of Mexico City. All five patients had epidemiologic risk factors, fever and a multisystemic illness, and two underwent laparotomy for acute abdominal syndrome. One patient died and four recovered completely. Problems in clinical and laboratory diagnosis are discussed. Leptospirosis should be suspected in patients with fever, jaundice and multiorgan involvement, and a proper epidemiologic setting.

Adult↗
PubMed2000

[Endemic and imported severe leptospirosis (Weil's disease) in southern Switzerland].

We report on 4 cases of severe icteric leptospirosis. Three patients developed renal failure requiring haemodialysis and one required mechanic ventilation for 10 days. On entry all patients presented with severe myalgia, particularly in the calves, jaundice, oligo-anuria and severe thrombocytopenia. In one case an acute abdomen-like presentation led to exploratory laparotomy. We believe that the abdominal pain was mainly due to rhabdomyolysis of the abdominal wall. The outcome was favorable in all cases and recovery of renal function was observed after a few days to several weeks. Three out of 4 patients were infected in southern Switzerland. This observation underscores the importance of wild and domestic animals as a leptospira reservoir. Patients presenting with acute renal failure and jaundice, but only mild-to-moderate elevation of transaminases, are suspect for leptospirosis regardless of travel to a tropical or subtropical country.

Acute Kidney Injury↗