Brain function and macromolecules. II. Site of increased labeling of RNA in brains of mice during a short-term training experience.
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The blood flow to a given brain region increases as the level of neural activity is augmented. Hence mapping of variations in regional cerebral blood flow affords a means of imaging the activity of various brain regions during various types of brain work. The paper summarizes the patterns of cortical activity seen during various language functions, emphasizing the practically symmetrical involvement in both hemispheres. A case of auditive agnosia (with complete cortical word deafness but preserved pure tone thresholds) is presented. The patient's normal speech constitutes evidence that auditory feedback (absent in his case) is not a prerequisite for speaking.
A report on investigations with Piracetam, recently introduced into therapy, is given. Piracetam is mainly characterized by cerebral metabolic effects, leading to an activation of cerebral functions as well as to brain protection. Experimental studies showed the highly selective activity of Piracetam on cerebral cortex, which is responsible for higher mental functions as consciousness, vigilance and memory. Therapeutic results in 48 adolescents with poor school results are reported. These patients were treated with Piracetam for a continuous period up to 14 months. The therapy lead to convincing improvements in terms of school results.
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