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Risk of vaccinia transfer to the hands of vaccinated persons after smallpox immunization.

Transmission of vaccinia virus after smallpox vaccination is a concern. We conducted a prospective examination of the protection afforded by vaccination-site bandages in recently vaccinated individuals. After smallpox vaccination, inoculation sites were covered with 2 occlusive dressings. Site assessment and bandage changes occurred every 3-5 days until the site was healed. At each visit, specimens from the vaccination site, outer dressing surface, and contralateral hand were obtained for vaccinia culture. For 148 vaccinated subjects, vaccinia was detected from vaccination lesions of every subject on several occasions. Only 6 (0.65%) of 918 dressing (95% CI, 0.24%-1.4%) and 2 (0.22%) of 926 hand (95% CI, 0.03%-0.78%) specimens tested positive for vaccinia. The mean number of bandage changes was 9.6 (95% CI, 9.17-10.0). Vaccinia autoinoculation did not occur. The rate of vaccinia recovery outside occlusive bandages covering smallpox vaccination sites was remarkably low, suggesting excellent protection against inadvertent transmission.

Adult↗

[Properties and acceptance of Melolin wound dressing in postoperative management of male urethral reconstruction].

In a prospective study we examined the quality and acceptance of the non-adhesive wound dressing Melolin during postoperative treatment following urethral reconstruction in 30 male patients. The wound dressing was cut individually for each patient and sterile Bepanthen ointment was applied to it. We fixed the dressing with a cohesive elastic bandage (Easifix Cohesive) and three cutaneous stiches and left it in place for 9 days. Both acceptance and absorbance of this bandage were good. Complete removal of the wound dressing was possible with no problems, although a camomile-water bath was necessary in two cases. No wound infections were observed. As functional and cosmetic results are so good, we now use this wound dressing routinely.

Adolescent↗

Characteristics and uses of biologic dressings and skin substitutes.

Biologic dressings used for temporary coverage of open wounds exert both mechanical and physiologic effects by protecting the wound, maintaining microbial control, and hastening wound maturation. Synthetic wound dressings modeled after the biologic dressings have been evaluated by several investigators. Those studies have shown unilaminate synthetic membranes to be ineffective when applied to full-thickness wounds and have identified a bilaminate construction as being necessary for membranes to serve as effective skin substitutes. The desirable properties of skin substitutes have been identified and incorporated in the design of recently developed membranes. Recent studies in this and other laboratories have resulted in the development of collagen-synthetic bilaminates, a totally synthetic biologically inert bilaminate, and tissue culture-derived membranes. The characteristics and limitations of each skin substitute determine the optimum usage of these composite membranes and define the modifications needed to improve the effectiveness of such dressings.

Animals↗

Treatment of leg ulcers.

A system of treatment of venous leg ulcers by leg elevation, dry gauze dressings and inelastic bandage boots is compared with regimens in which a series of elastic bandage boots are applied to squeeze oedema from swollen ulcerated legs.

Bandages↗

Allevyn adhesive.

Allevyn Adhesive is a development of Allevyn Hydrocellular produced by Smith & Nephew Healthcare. Allevyn Adhesive comprises three layers and has the same absorbency as Allevyn Hydrocellular. The dressing is waterproof and requires no secondary dressing, tape or bandages. It is able to conform to the most awkward body areas such as the sacrum, heels and elbows. It is suitable for use on a variety of exuding wounds and can be used in conjunction with a hydrogel for sloughy wounds.

Aged↗

Does the use of low-level laser influence wound healing in chronic venous leg ulcers?

OBJECTIVE: Venous leg ulcer treatment often requires months or years of regular wound care by trained staff. It has been suggested that low-level laser irradiation has a biostimulative and wound healing effect, but this has not been clinically verified by controlled studies. This study aimed to compare the effectiveness of low-level laser irradiation with that of a placebo 'light source'. METHOD: Forty-four patients were assigned to two treatment groups (laser and placebo) or a third group (standardised treatment only) to quantify the effect of the laser therapy. Patients in all three groups received standardised wound care (disinfection, a hydrofibre dressing and compression bandaging). Ulcer size was measured at baseline (day 1), at the end of therapy (day 28) and then two months later (day 90). The relative difference in wound size was evaluated. RESULTS: The difference in the reduction in wound size was not statistically significant in all three groups. A positive effect of using the non-laser device (placebo effect) was demonstrated in some patients. CONCLUSION: These study results suggest that low-level laser does not stimulate wound healing in venous leg ulcers. Further controlled studies are needed to clarify the efficacy of low-level laser treatment as a wound-healing stimulant.

Adult↗