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Results for “DENTAL PULP CAPPING”

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At least 217 records · Page 12Linked to original sources
PubMed2004

Dentin regeneration by dental pulp stem cell therapy with recombinant human bone morphogenetic protein 2.

Regenerative medicine is based on stem cells, signals, and scaffolds. Dental pulp tissue has the potential to regenerate dentin in response to noxious stimuli, such as caries. The progenitor/stem cells are responsible for this regeneration. Thus, stem cell therapy has considerable promise in dentin regeneration. Culture of porcine pulp cells, as a three-dimensional pellet, promoted odontoblast differentiation compared with monolayers. The expression of dentin sialophosphoprotein (Dspp) and enamelysin/matrix metalloproteinase 20 (MMP20) mRNA confirmed the differentiation of pulp cells into odontoblasts and was stimulated by the morphogenetic signal, bone morphogenetic protein 2 (BMP2). Based on the in vitro experiments, an in vivo evaluation of pulp progenitor/stem cells in the dog was performed. The autogenous transplantation of the BMP2-treated pellet culture onto the amputated pulp stimulated reparative dentin formation. In conclusion, BMP2 can direct pulp progenitor/stem cell differentiation into odontoblasts and result in dentin formation.

Animals↗
PubMed2005

Effectiveness of 4 pulpotomy techniques--randomized controlled trial.

Pulpotomy is the accepted therapy for the management of cariously exposed pulps in symptom-free primary molars; however, evidence is lacking about the most appropriate technique. The aim of this study was to compare the relative effectiveness of the Er:YAG laser, calcium hydroxide, and ferric sulfate techniques with that of dilute formocresol in retaining such molars symptom-free. Two hundred primary molars in 107 healthy children were included and randomly allocated to one of the techniques. The treated teeth were blindly re-evaluated after 6, 12, 18, and 24 months. Descriptive data analysis and logistic regression analysis, accounting for each patient's effect by a generalized estimating equation (GEE), were used. After 24 months, the following total and clinical success rates were determined (%): formocresol 85 (96), laser 78 (93), calcium hydroxide 53 (87), and ferric sulfate 86 (100). Only calcium hydroxide performed significantly worse than formocresol (p = 0.001, odds ratio = 5.6, 95% confidence interval 2.0-15.5). In conclusion, calcium hydroxide is less appropriate for pulpotomies than is formocresol.

Calcium Hydroxide↗
PubMed2002

Preserving the vital pulp in operative dentistry: 3. Thickness of remaining cavity dentine as a key mediator of pulpal injury and repair responses.

Confusion surrounds the pivotal role played by the remaining dentine thickness in a cavity in determining pulpal injury and repair response outcomes after restorative treatment. The multifactorial nature of the injury repair response requires that attention is focused on the most important factors, including remaining dentine thickness, to harness the natural regenerative properties of the pulp and to avoid postoperative treatment complications.

Cell Count↗
PubMed1979

Pulpectomy procedure for deciduous teeth with severe pulpal necrosis.

Pulpectomies of deciduous teeth with severe pulpal necrosis should be considered as a possible treatment plan. Systemic and dental criteria have been devised to help the clinician to select cases in which successful results may be produced. A clinical success occurs when the pulpectomized tooth is painless, is firm in its alveolar socket, and is without a fistulous tract. Radiographically, any radiolucent area should be resolving with six months, and no pathologic root resorption should be observed. Research should determine whether pulpectomies may be done on children with severe systemic disease and should determine long-term consequences of underfilled and overfilled pulpectomies.

Dental Pulp Capping↗
PubMed2005

How to kill a tooth.

Many dentists report increased activity in endodontic therapy. Although retention of teeth through most of life by many patients and the aging population are potential reasons for this increase, it is possible that some of the new dental procedures, instruments or materials that have become popular in recent years also are significant causative factors. Several potential preventable reasons for increased pulpal death and the resultant need for endodontic therapy are discussed in this article.

Composite Resins↗
PubMed2006

Mineral trioxide aggregate pulpotomies: a case series outcomes assessment.

BACKGROUND: The greatest threats to developing teeth are dental caries and traumatic injury. A primary goal of all restorative treatment is to maintain pulp vitality so that normal root development or apexogenesis can occur. If pulpal exposure occurs, then a pulpotomy procedure aims to preserve pulp vitality to allow for normal root development. Historically, calcium hydroxide has been the material of choice for pulpotomy procedures. Recently, an alternative material called mineral trioxide aggregate (MTA) has demonstrated the ability to induce hard-tissue formation in pulpal tissue. The authors describe the clinical and radiographic outcome of a series of cases involving the use of MTA in pulpotomy procedures. METHODS: Twenty-three cases in 18 patients were treated with MTA pulpotomy procedures in an endodontic private practice. All of the patients had been referred to the practice for diagnosis and treatment of a symptomatic tooth. All of the authors provided treatment. Pulpal exposures were either due to caries or complicated enamel dentin fractures. RESULTS: Nineteen teeth in 14 patients were available for recall. The mean time of recall was 19.7 months. Of the 19 cases, 15 involved healed teeth, and three involved teeth that were healing. One of 19 cases involved a tooth with persistent disease. CONCLUSIONS: MTA may be useful as a substitute for calcium hydroxide in pulpotomy procedures. Further research, however, is required to clarify this conclusion. CLINICAL IMPLICATIONS: MTA conceivably could replace calcium hydroxide as the material of choice for pulpotomy procedures, if future research continues to show promising results.

Adolescent↗
PubMed2000

Pulpal evaluation of two adhesive systems in rat teeth.

Formocresol is the agent most frequently used with pulpotomies in primary teeth, but its use is currently under discussion in regard to its possible toxic effects. Some current works suggest the use of dentinal adhesives in cavities with minimal dentinal thickness and even in small pulpal exposures. Our objective was to evaluate pulpal response to the application of two dentinal adhesives Syntac and Prime & Bond NT in pulpal exposures in rat teeth. Sprague Dawley rats were used, male, 150 to 200 gm in weight. The maxillary first molar, left and right, was employed in each case, a total of twelve teeth. Duration of the study was 45 days. Sections were evaluated using a light microscope in order to determine pulpal response to the two adhesives. In both groups the persistence of chronic inflammation was associated with the absence of dentinal bridges in the affected specimens. Areas of necrosis and absence of regularity of the odontoblastic layer could also be seen.

Animals↗
PubMed1980

A new approach to vital root resection.

This report deals with ten cases in which periodontal surgery was performed followed by immediate resection of one of the vital buccal roots on maxillary molars. The resultant pulpal opening was treated with calcium hydroxide, zinc oxide and eugenol then sealed with an amalgam alloy. Two additional cases were treated in reverse order by first resecting the vital root followed by immediate periodontal surgery. All cases were evaluated over a 1 to 3 year period. The results indicate that vital root resection at the same time as periodontal surgery compares favorably with cases treated in which periodontal surgery was completed at a prior appointment.

Adult↗
PubMedDate not supplied

Caries and dentin. Myths & consequences.

The dentin-pulp complex is sensitive to infection. Restorative treatment should function as a Band-Aid protecting the dentin-pulp complex from bacteria and their byproducts. This article describes different ways of treating the exposed dentin-pulp complex in such a way that bacterial infection can be avoided.

Dental Caries↗