PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Electrocoagulation”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 217 records · Page 12Linked to original sources

Palliative bipolar electrocoagulation therapy of obstructing esophageal cancer.

In a multicenter pilot study, a prototype bipolar electrocoagulation tumor probe was employed for palliation of obstructing circumferential esophageal cancer in 20 patients. Mean number of initial treatment sessions was 1.7. Dysphagia and tumor channel size improved significantly after treatment. Mean treatment interval before repeat treatment was 7.6 weeks. Major complications included delayed hemorrhage (two patients) and esophageal-pulmonary fistula (two patients). This new device may provide a less expensive alternative to laser or surgery for palliation of malignant esophageal obstruction.

Adenocarcinoma↗

A randomized comparison of multipolar electrocoagulation and injection sclerosis for the treatment of bleeding peptic ulcer.

Several options are available to the gastroenterologist for the endoscopic control of peptic ulcer hemorrhage. Sixty men (mean age, 62 years) were stratified into those with actively bleeding ulcers or ulcers with stigmata of recent hemorrhage, and then randomized to treatment with injection sclerosis or the multipolar probe until bleeding ceased. There were no significant differences between the randomized groups in terms of age, ulcer size, or transfusion requirements. We achieved hemostasis in 95% of all patients. Re-bleeding rates were 25% and 23% in patients treated with the multipolar probe and injection sclerosis, respectively. There was no significant difference in mortality (14% multipolar probe, 7% injection sclerosis). Patients over the age of 70, those whose onset of bleeding was while an inpatient, and those with an ulcer larger than 2 cm were more likely to have a poor outcome, regardless of the type of endoscopic therapy. Injection sclerosis and multipolar electrocoagulation are equally effective in controlling bleeding from peptic ulcer.

Adult↗

Reversal of Barrett's esophagus with acid suppression and multipolar electrocoagulation: preliminary results.

BACKGROUND: Barrett's esophagus is a premalignant lesion for esophageal adenocarcinoma. This study tests the hypothesis that re-injury of the metaplastic the epithelium in an acid-controlled environment will result in reversal of Barrett's to squamous epithelium. METHODS: Patients with at least 2 cm of Barrett's esophagus were treated with omeprazole, and half the circumference of the Barrett's was treated with multipolar electrocoagulation (MPEC); the other half served as an internal control. After 6 months, the remaining Barrett's esophagus was treated with MPEC. RESULTS: Twenty-four hour esophageal pH of less than 4 averaged 1.8% on a mean dose of 56 mg/day of omeprazole. Ten patients had visual and biopsy elimination of the targeted section of Barrett's esophagus after an average of 2.5 MPEC sessions. The remainder of the Barrett's esophagus is being treated in 9 patients; currently 5 have no evidence of Barrett's. CONCLUSIONS: The combination of control of esophageal acid exposure and reinjury of the metaplastic epithelium reverses Barrett's esophagus to squamous epithelium as determined by endoscopy and biopsy.

Aged↗

Antireflux surgery followed by bipolar electrocoagulation in the treatment of Barrett's esophagus.

BACKGROUND: Management of Barrett's esophagus requires reduction of gastric acid secretion and screening for the development of adenocarcinoma. However, the current therapeutic options are ineffective in reducing the Barrett's mucosa. The aim of this study was to evaluate the effectiveness of endoscopic thermal coagulation of Barrett's mucosa as an alternative therapeutic approach and the recurrence of the disease in the long term. METHODS: Fourteen patients (11 men, 3 women; mean age 45.7 years) with Barrett's esophagus participated in the study. They underwent laparoscopic fundoplication and were symptom free with no defective fundoplication wraps before therapeutic endoscopy. Endoscopic thermocoagulation was performed with a flexible videoendoscope and a bipolar probe. Mucosal areas were treated once a month until the Barrett's mucosa disappeared. Endoscopy was performed 1 and 7 months after completion of the treatments and once a year thereafter. RESULTS: The mean follow-up period was 21.6 months (range 18 to 30 months). The mean length of Barrett's esophagus was 4.8 cm. Successful ablation of the columnar epithelium was achieved in 3.7 sessions, as defined by demonstration of normal squamous epithelium at histologic examination of biopsy samples collected after completion of the treatments and at follow-up evaluations. Three patients experienced short-term (10 days) odynophagia or dysphagia. All patients were symptom free with no evidence of Barrett's esophagus at the end of the study. CONCLUSIONS: Bipolar electrocoagulation after antireflux operations is effective in promoting regression of Barrett's esophagus and has few complications. Endoscopic thermal coagulation might reduce risk for adenocarcinoma among these patients.

Adolescent↗

Regression of childhood Barrett's esophageal mucosa by antireflux surgery and bipolar electrocoagulation.

The authors report a case of a 13-year-old girl with Barrett's esophagus who underwent antireflux surgery and was subsequently treated with endoscopic thermal coagulation using bipolar electrocoagulation. Follow-up endoscopy 15 months after completion of the endoscopic therapy showed normal esophageal mucosa without intestinal metaplasia. Longer follow-up is needed to assess the long-term effects of endoscopic treatment of the Barrett's mucosa with thermal coagulation, and this procedure should still be considered under investigation.

Adolescent↗

Pregnancy following the laparoscopic bipolar electrocoagulation of polycystic ovaries resistant to medicamentous ovulation induction--a case report.

The case of a primarily infertile patient with polycystic ovaries (PCOS) resistant to medicamentous ovulation induction is presented. The preoperative condition, laparoscopic ovarian drilling using an original technique of bipolar electrocoagulation and consecutive spontaneous pregnancy and delivery are described. This case suggests that bipolar forceps with jaws 1 mm wide could be a useful instrument for laparoscopic ovarian drilling.

Adult↗

Multipolar electrocoagulation.

Multipolar electrocoagulation (MPEC) is a readily available technique that can be applied for endoscopic ablation of Barrett's esophagus. MPEC, in combination with high dose proton pump inhibitor therapy or antireflux surgery, results in normal squamous epithelium in most patients without major adverse effects. The ultimate clinical role of MPEC has not been determined but may be adjunctive to other techniques in appropriately selected patients at high risk for neoplastic progression.

Barrett Esophagus↗

Monopolar versus bipolar electrocoagulation in canine laparoscopic ovariectomy: a nonrandomized, prospective, clinical trial.

OBJECTIVE: To compare the effect of using monopolar (MEC) or bipolar electrocoagulation (BEC) on surgical time for laparoscopic ovariectomy in dogs and to evaluate the influence of age, weight and obesity, and estrus or pseudopregnancy on surgical time. STUDY DESIGN: Prospective, nonrandomized, clinical trial. ANIMALS: One hundred three female dogs. METHODS: Laparoscopic ovariectomy was performed with MEC or BEC by 1 surgeon using a standard protocol. Surgical time was recorded for the different procedural stages and was statistically evaluated for differences between MEC and BEC (chi(2), Student t test, and ANOVA). The influence of significant variables was analyzed using multiple linear regression analysis. RESULTS: Mean surgical time was 47 minutes (range, 27 to 110 minutes). With BEC, surgical time was significantly shorter (41 minutes; P <.001) than with MEC (53 minutes). Obesity (56 vs. 42 minutes; P <.001) and intraoperative mesovarial bleeding (56 vs. 46 minutes; P =.03) increased surgical time. Dog age, estrus, and pseudopregnancy did not significantly influence surgical time. CONCLUSIONS: BEC decreased laparoscopic ovariectomy time, decreased intraoperative hemorrhage, and, with the technique used, facilitated exteriorization of the ovaries. CLINICAL RELEVANCE: Laparoscopic ovariectomy can be performed more rapidly when using BEC instead of MEC and with less risk of mesovarial hemorrhage.

Animals↗

The healing process of experimentally produced bleeding lesions after hemostatic electrocoagulation with simultaneous instillation of water.

Fifty experimentally induced, standardized gastric bleeding lesions were successfully arrested in the dog using electrocoagulation with simultaneous instillation of water (EHT-coagulation). The contact pressure of the coagulating electrode was kept almost constant by means of a spring mechanism. The coagulated lesions healed without secondary enlargement of the coagulation effect and without complication. No secondary perforations were observed. Even when coagulation was carried out at an output power about 30% higher than the mimimum power necessary for reliable hemostatic coagulation, no complications were observed. Only with additional post bleeding arrest coagulation in excess of 10 seconds at this higher output, were two primary performations produced in 2 out of 12 cases. The non-perforated remaining 10 lesions healed without complication. With additional coagulation (at power output setting 6 for 20 seconds - 8 cases; at power setting 7 for 10 seconds - 6 cases), no perforations were observed and healing was without complications. Thus, in animal experiments, the therapeutic range for the arrest of bleeding using the electro-hydro-thermo-electrode is adequately large. The technique should be tested in clinical trials.

Animals↗

[Percutaneous electrocoagulation of posterior ramus of spinal nerves in pain relief treatment of spondylogenic low back pain (author's transl)].

The author presents his results on 70 patients under treatment of low back pain by means of electrocoagulation of the posterior ramus of spinal nerves. In many cases of disc hernia it was possible to attain good results that enabled us to abandon the operative procedure. The best results were achieved in cases of sciatalgic pains, which were diminished more considerably than the local lumbosacral ones. When conservative methods fail, and no absolute operative indications exist, coagulation may be helpful in pain relief.

Back Pain↗

[The electro-hydro-thermal probe. Clinical results and possible use of modified electrocoagulation in the gastrointestinal tract].

Electrocoagulation with simultaneous water infusion (electro-hydro-thermal probe) was applied in 58 patients. In 43 there had been active bleeding which was stopped in over 90%. The use of this probe thus proved to be of clinical importance for endoscopic arrest of bleeding. Non-bleeding lesions, most of them vascular changes, were coagulated in 15 patients, removing a potential source of bleeding. There were no complications.

Electrocoagulation↗

Vital pulp therapy with bipolar electrocoagulation after intentional pulp exposure of fixed prosthodontic abutments: a clinical report.

A clinical protocol is described for the treatment of intentional and unavoidable exposed pulps during crown preparation. The protocol includes a definitive cavity preparation to create space in the exposed dentin for an adhesive pulp barrier; procedures to develop the highly desirable hybrid zone to prevent microleakage; the use of a specific resinous material that serves as a long-term pulp barrier with a relatively neutral and biocompatible impact on the pulp; and the use of precise bipolar electrocoagulation to provide durable hemostasis for restoration of the pulp wall and a relatively clot-free surgical wound to facilitate healing. The protocol involves the application of gentle surgical and restorative procedures to support the inherent healing process to restore the health of the pulp. The patient presented was part of a larger investigation and was selected in an attempt to identify a fixed prosthodontic application of the proposed pulp therapy protocol.

Acrylic Resins↗

Recovery and utilization of useful by-products from egg processing wastewater by electrocoagulation.

The efficacy of a laboratory electrocoagulation (EC) system for treating egg processing plant waste-water (WW) is reported. For simulated and industrial egg processing WW, chemical oxygen demand, turbidity, and total suspended solids (TSS) were reduced 92 to 97%, 97%, and 99%, respectively, after treatment with EC. The final TSS concentration and turbidity values were 30 mg/L and 5 formazin turbidity units (FTU), respectively, similar to that of potable water standards. The recovered by-product solids had a similar pattern of essential amino acids compared to that of liquid whole egg and were comparable to the Food Agriculture Organization's essential amino acid profile for an ideal protein. The relative protein digestibilities of the recovered solids and a commercial corn meal averaged 130 and 56%, respectively, compared to liquid whole egg (set at 100%). An economic analysis of EC indicated that this treatment is economically feasible in that a savings of approximately $425,000 per year is possible in addition to recovering the capital equipment costs after about 14 mo of operation. These findings demonstrate that EC can be successfully applied to treat egg processing plant WW, yielding a high quality water suitable for recycling and valuable by-products having a highly digestible protein and fat value.

Agriculture↗

Transcatheter electrocoagulation: experimental evaluation of the anode.

Transcatheter electrocoagulation using direct current has been shown to be an effective method for vessel occlusion. To date, the stainless steel anode has not been entirely satisfactory. Thus, an evaluation of bipolar platinum electrodes and a comparison of monopolar platinum and stainless steel electrodes have been performed. Experimental results have shown that both monopolar and bipolar platinum electrodes caused perforation in most cases. At the present time, we have not found a satisfactory replacement for the unipolar stainless steel anode.

Animals↗

Transcatheter electrocoagulation of the pulmonary artery: an experimental model in dogs for studying pulmonary thrombosis.

Transcatheter electrocoagulation (TCEC) has been shown to produce permanent arterial occlusion. This study was performed to evaluate the potential of using TCEC of the pulmonary artery as an experimental model of pulmonary thromboembolism. Fourteen lobar or first-order pulmonary arteries were occluded in ten dogs in the acute studies. Eight pulmonary arteries were occluded in eight dogs that were sacrificed 25 to 85 days after TCEC. There were permanent occlusions in seven, and all seven evidence of pulmonary infarction. The animals tolerated the procedure well. The technique may have merit as an experimental model for studying pulmonary thrombosis and infarction.

Animals↗

Effect of increasing current and decreasing blood flow for transcatheter electrocoagulation (TCEC).

Arterial occlusion by direct-current transcatheter electrocoagulation (TCEC) has been developed experimentally and used successfully in clinical situations. The major shortcoming of the technique has been the lengthy time necessary for occlusion of larger arteries. In the present study we attempted to decrease the time necessary for TCEC occlusion of the renal and femoral arteries of heparinized mongrel dogs. The results showed that the occlusion time could be significantly decreased, either by increasing the TCEC current from 15 ma to 30 or 60 ma, or by using a Meditech balloon catheter to occlude the artery during TCEC. The combination of higher current and simultaneous balloon occlusion consistently produced permanent occlusion of arteries up to 7 mm in diameter in 15 minutes or less. Balloon occlusion with TCEC is significantly faster than without this modification and makes the technique of TCEC more applicable for human use and for continued experimental study than any previous refinements.

Animals↗

The mechanism of transcatheter electrocoagulation (TCEC).

This study was performed to evaluate the temperature, pH change, and electrolysis products at the anode during transcatheter electrocoagulation (TCEC). Stainless steel and platinum anodes insulated by standard angiographic catheters were placed in renal dialysis tubing. The tubing, filled with either saline solution or plasma, was placed in a water bath (25 degrees C) containing a cathode. Temperature was recorded at the tip of the anode, placed in saline solution, using 15 ma for 20 minutes (n = 5 for each wire and current). pH was measured during applications of 15, 30, and 60 ma for 20 minutes (n = 6 for each current, anode, and solution). The solutions were analyzed for products of electrolysis. The temperature remained constant. The pH declined to 1.5 +/- .3 (mean +/- SEM) with the platinum electrode and to 2.5 +/- .5 with the stainless steel anode. Metallic elements and oxygen were the electrolysis products recovered from the stainless steel experiments. Chlorine gas was the major product recovered from the platinum studies. These results confirm that during TCEC there is no thermal injury. The pH change at the anode is probably a major mechanism in TCEC. Different types of reactions take place at platinum and stainless steel anodes, which may account for differences between TCEC with these two electrodes.

Catheterization↗

Evaluation of embolization distal to arterial occlusion by transcatheter electrocoagulation (TCEC) and Gianturco coils.

A technique was developed to evaluate the degree of embolization distal to arterial occlusion by transcatheter electrocoagulation (TCEC) and Gianturco coils. The kidneys of mongrel dogs were used to collect emboli distal to conventional TCEC or Gianturco coil occlusion of the renal arteries. TCEC controls (TCEC setup without current), normal kidneys, kidneys embolized with autologous clot, and kidneys whose renal arteries were surgically ligated were evaluated for comparison. The renal vasculature was flushed and then fixed by glutaraldehyde infusion. The kidneys were filled with a barium gelatin mixture and examined both radiographically and pathologically. The four normal kidneys and the four ligated kidneys gave a characteristic complete filling of the vascular web, while filling defects were evident in the following conditions: 3/12 TCEC controls; 26/34 with TCEC occlusion; 6/10 with Gianturco coils; and 11/11 with autologous clot. An excellent correlation existed between radiographic intraluminal filling defects and grossly and microscopically identified emboli.

Animals↗