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Results for “GENERAL ADAPTATION SYNDROME”

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At least 217 records · Page 12Linked to original sources
PubMed1983

[Biological role of the reactive inhibition of mitoses during stress].

The course of cell division processes under the influence of various stressors reflecting the main variants of the general adaptation syndrome were studied in corneal epithelium. The process of cell division was assessed by counting mitoses, including pathological ones, and by autoradiographic and cytophotometric analysis of interphase. In the adequate course of the general adaptation syndrome, lengthening of G2-period provoked by enhanced secretion of adrenal hormones and causing a decrease in the number of mitoses occurs in the first hours of stress, the level of pathological mitoses and DNA synthesis remaining stable. When stress was exerted on adrenalectomised rats, the premitotic period did not increase, the number of mitoses did not decrease, the number of pathological mitoses, however, increased, their spectrum extended, DNA synthesis was altered. Adrenal hormones are considered to be an important part of the functional system of mitosis contributing to the maintenance of host genetic stability.

Adrenal Cortex↗
PubMed1989

Constructive integration of learning theory and phenomenological approaches to biofeedback training.

Two major sources of theoretical development for biofeedback as an intervention paradigm are considered. An integration of cognitive learning theory approaches to the potential regulation of autonomic processes in an information-processing framework and the phenomenological information-processing approach of Kelly's personal construct theory suggest a new methodological paradigm for biofeedback as a tool of psychotherapeutic intervention, especially for the discipline of behavioral medicine. Biofeedback is reconstructed as a sequence of allocating attention to automatic cognitive processes until cognitive control has been mastered. This sequence is also seen as a circumspection-preemption-control cycle that Kelly (1955) suggested was essential to all problem solving. In light of Kelly's fundamental assumptions regarding the nature of constructs, it is suggested that controlled processing approaches to biofeedback require the biofeedback trainee to investigate both ends of psychophysiological dichotomies instead of demonstrative constructs of traditional biofeedback methodology. Other psychotherapeutic techniques are reviewed to validate this new theoretical approach. Finally, treatment within this paradigm is discussed as a recircumspection of relevant constructs that were routinized during the alarm reaction phase of Selye's general adaptation syndrome.

Biofeedback, Psychology↗
PubMedDate not supplied

[The lysosomal acid phosphatase activity of the peripheral blood neutrophilic leukocytes in inflammation].

The investigation was carried out on 56 adult rabbits. The level of activity of lysosomal acid phosphatase in blood, its dependence on a degree of degranulation of granulocytes and interaction of these processes on parametres of some humoral systems of blood controlled by the Hageman factor were investigated under conditions of aseptic inflammation caused by intramuscular injection of formaline. The conclusion is made that exocytosis of lysosomal enzymes and changes in activity levels of some humoral systems controlled by them under conditions of inflammation are nonspecific components of a general adaptation syndrome.

Acid Phosphatase↗
PubMedDate not supplied

[Morphofunctional changes in the lysosomal apparatus of the peripheral blood neutrophilic leukocytes in aseptic inflammation].

The investigation was carried out on 47 adult rabbits. The reaction of lysosomal apparatus of neutrophilic leucocytes of peripheral blood was investigated under conditions of aseptic inflammation, caused by intramuscular injection of formaline. The conclusion is made that neutrophilic leucocytosis and a decrease of lysosomes in neutrophils under conditions of inflammation are nonspecific components of a general adaptation syndrome and result from the vivid granulocytopoesis and leucergy process.

Animals↗
PubMed1986

Magnetostatic field effect: stress syndrome pattern and functional relation with intensity.

The stressing action of a medium-intensity, magnetostatic field was studied for several levels of intensity. Our purpose was to verify a stressing action by display of the general adaptation syndrome pattern on the growth rate of mice and to establish the relation between effect and field intensity on the same variable. Eight groups of mice showed a linear relation. Moreover, stressing action was noticed at lower intensities than previously suggested.

Animals↗
PubMed1979

Sensory deprivation and homeostasis.

Most afferent inputs are sensory stimulants, and physical activity is probably one of the most significant of all sensory stimulations. Gravity is a constant stimulus. These demands are also known as stress, and the stressor effect as the general adaptation syndrome (Selye). In this study, these demands are called sensory afferent stimuli, which are necessary triggers to start the hypothalamus-pituitary-adrenal mechanism and thus maintain the general mechanical, autonomic and metabolic functions of the body in the state of homeostasis. If the sensory stimulus is removed, there is no stressor effect and the cycle of response is eliminated. This results in a decreased hypothalamus-pituitary response and a decreased production of ACTH and corticoids. A decrease in the sensory input creates changes in the central nervous system and in the musculoskeletal system which are compatible with lack of the hypothalamus-pituitary responses. When a person becomes ill, physical inactivity as well as sensory and perceptual deprivation are at a maximum, and the absence of these stimuli interrupts the cycle of homeostasis. Physical activity is one of the most important stressors (sensory input) or triggering mechanisms for the cycle of homeostasis (hypothalamus-pituitary-adrenal cycle). Therefore, it is imperative to provide the patient with physical activities which ensure motion and take into account the effect of gravity. This is best accomplished by a program of physical, occupational and recreational therapy.

Aged↗
PubMedDate not supplied

[Stress among public safety and security forces. Genetic and physiopathology].

Hans Selye used the word "stress" exactly 68 years ago, in hi paper "A syndrome produced by diverse nocuous agents", published in Nature. The syndrome termed as "stress" induces hormonal autonomic responses and, over time, these hormonal changes can lead to ulcers, high blood pressure, arteriosclercosis, arthritis, kidney disease and allergic reactions. The aim of this study is to analyse the General Adaptation Syndrome (GAS), the response of the body to external stimuli, and the current knowledge about biochemistry, physiology and stress genetics. The police forces work is a complex profession, particularly liable to stress disease, as the adverse occurrences of the social life add to the stressing events specifics of callings regarding public order keeping. The results of the present study suggests the advisability of instituting a preventive monitoring for these workers.

Feedback↗
PubMed1980

Fatigue: towards an analysis and a unified definition.

Fatigue is the commonest, yet least understood and most neglected symptom in medicine. A physiological formula for fatigue is proposed, based on the concept of a reduction of the "latent capacity" of cells, tissues and organs whose states are constantly monitored by the brain. Reduced "latent capacity" is postulated as being the sought-after, non-specific alarm signal of the General Adaptation Syndrome of Selye (G.A.S.). The relationship between fatigue and pain is discussed. Reduced "latent capacity" is postulated as being the common thread in the different kinds of fatigue - physiological, pathological, psychogenic, acute and chronic.

Blood-Brain Barrier↗