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At least 217 records · Page 12Linked to original sources
PubMed1992

[The diagnosis of congenital heart defects today. Part 1: Ventricular septal defect, pulmonary stenosis, patent ductus arteriosus, atrial septal defect].

Most congenital heart diseases are detected in childhood, but some, such as atrial septal defect, can remain undiagnosed until adulthood. In the first part of this review, taking the auscultation findings and the clinical picture as a basis, the diagnosis of four common congenital heart diseases is discussed: ventricular septal defect, pulmonary stenosis, patient ductus arteriosus, and atrial septal defect. In addition, the latest developments in the field of therapy are briefly considered.

Ductus Arteriosus, Patent↗
PubMed2000

Nuchal translucency and congenital heart defects: heart failure or not?

OBJECTIVE: To determine whether heart failure is the mechanism underlying the association between increased fetal nuchal translucency and congenital heart defects. METHODS: Retrospective analysis of the types of congenital heart defect observed in fetuses with increased nuchal translucency and those with normal nuchal scans. Retrospective quantitative analysis of cardiac size and left ventricular ejection fraction in fetuses with ventricular septal defects or the hypoplastic left heart syndrome. RESULTS: Eighty-three fetuses with congenital heart defects had undergone nuchal screening of which 51 had increased nuchal translucency and 32 had normal nuchal translucency. A wide variety of different congenital cardiac lesions with different hemodynamic effects were observed in fetuses with increased nuchal translucency and those with normal nuchal scans. Defects primarily characterized by left heart obstruction, right heart obstruction and septal defects occurred in both groups. All measurements of cardiothoracic ratio and left ventricular ejection fraction fell within the normal range and there was no significant difference between fetuses with increased nuchal translucency and those with normal nuchal scans. CONCLUSIONS: No specific type of congenital heart lesion is associated with increased nuchal translucency. The contention that heart failure explains the association between congenital heart defects and increased nuchal translucency is not supported by this study.

Heart Defects, Congenital↗
PubMed1990

[Angiocardiographic diagnosis of atresia of the right atrioventricular orifice and associated congenital heart defects].

Ninety patients with atresia of the right atrioventricular orifice were examined. Their ages ranged from 3.5 to 24 years (9.9 +/- 0.5 years on the average). Stenosis of the pulmonary artery was found in 86 patients and was absent in 4 patients. Various intraarterial anastomoses had been established previously in 46 patients with stenosis of the pulmonary artery. All the patients were subjected to angiocardiographic examination including angiocardiography from the right and left parts of the heart and from the great vessels. Several anatomical variants of atresia of the right atrioventricular orifice and concomitant anomalies were studied. The following program of roentgeno-surgical examination in this complex congenital heart disease was elaborated. 1. Catheterization of the right and left parts of the heart and the great vessels. 2. Angiocardiography: right atriography; left ventriculography in anteroposterior, lateral, and, if indicated, axial views; aortography; pulmonary arteriography and, when indicated, right ventriculography.

Adolescent↗
PubMed1989

[Pathologic anatomy of congenital heart defects].

The heart of neonates and infants with marked hypoplastic left- or right-heart-syndrome contains--despite the very low weight in the hypoplastic parts--myocytes of approximately the same size as in the non-hypoplastic ventricular wall. This means that the number of cells is not constant, because in contrast to the regularly developed right and left ventricular walls, the total number of myocytes in the hypoplastic parts is significantly lower. Hypertrophy of the myocardium in congenital heart disease shows histological and ultrastructural findings that are similar to those found in other forms of myocardial hypertrophy. Hypertrophy is reversible after successful surgical correction. However, regression is often incomplete, especially if surgery is delayed until adolescent or adult life. During this time scar formation in the hypertrophic ventricular wall may develop. In addition to these scars, also postoperative scar formation may contribute to the origin of arrhythmias. In hearts with cyanotic and non-cyanotic vitia distances between capillaries and capillary lengths are approximately the same as in normal hearts. Obviously, these parameters are genetically determined.

Arrhythmias, Cardiac↗
PubMed2004

[Parachute mitral valve coexisting with complex congenital heart defect. Successful multistage surgical treatment].

Type parachute valve is a very rare bicuspid valve congenital anomaly. When signs of dysfunction are noted the valve has to be replaced with an artificial one. The case describes a 7-year old girl suffering from complex congenital heart defect: coarctation of the aorta followed by hypoplastic aortic arch, ventricular septal defect and parachute mitral valve. In the neonatal period the girl had been operated on by the subclavian floppy aortoplasty method due to coarctation of the aorta. At the age of 2, another surgical correction was performed: ventricular sept defect closure simultaneously with mitral valvuloplasty. In infancy she failed to thrive, also signs of heart failure had been observed which resulted from increasing mitral valve stenosis and III grade mitral insufficiency. These findings in with artificial valve replacement (type Sorin O 23 mm). Procedure has been performed by the left atrium. Post operational period was uneventful. Proper function of the implanted valve has been observed with no perivalvular leakage and left atrium diameter has been normalized.

Child↗
PubMed1998

Partial biventricular repair for complex congenital heart defects: an intermediate option for complicated anatomy or functionally borderline right complex heart.

BACKGROUND: Partial biventricular repair consists of bidirectional cavopulmonary anastomosis in the presence of separated systemic and pulmonary circulations, with antegrade flow of inferior caval return through an intact or reconstructed pulmonary outflow tract. This versatile procedure may be used as a definitive repair for patients with a functional right heart complex incapable of supporting an entire cardiac output or in patients with complicated anatomy. METHODS: From July 1992 to April 1997, 23 patients (median age 5.2 years) underwent partial biventricular repair. In 15 of these cases the entire repair, including bidirectional cavopulmonary anastomosis, intracardiac repair, and right ventricular outflow reconstruction, was performed as a planned procedure at our institution. The other eight patients had previously been placed on a Fontan track and had undergone bidirectional cavopulmonary anastomosis; their circulations were converted to a partial biventricular circulation. RESULTS: There were no early deaths. Complete atrioventricular block developed in two patients with straddling tricuspid valve. At a median follow-up of 17 months, there were no late deaths and three patients had undergone reintervention. Partitioning of the pulmonary arteries to create a classic Glenn anastomosis with antegrade flow to the left lung was performed in one case; another patient underwent an atrial septectomy, and the third patient required revision of tricuspid valve repair. All patients are in New York Heart Association functional class I. CONCLUSIONS: Partial biventricular repair is a versatile strategy that can be used to manage a variety of forms of complex congenital heart disease. Cases for which the repair is useful include those in which complete biventricular repair is unlikely to be achieved because of limited size or function of the right side of the heart and those in which a patient with a ventricle capable of supporting inferior vena caval return was previously placed on a Fontan track.

Abnormalities, Multiple↗