PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “ILEITIS, REGIONAL”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 217 records · Page 12Linked to original sources
PubMed1977

Long-term results in the treatment of regional ileitis with coherin.

Nineteen patients with severe symptoms of ileitis, not responsive to other forms of therapy, have been treated with coherin, a peptide isolated from bovine posterior pituitary glands. This study encompasses observations over a total of 50-patient years. tcoherin has proven efficacious by three criteria: As a result of coherin treatment those patients receiving steroids could either eliminate them or reduce the dosage to safe levels. A significant number of patients whose symptoms have been controlled by coherin have demonstrated their therapeutic dependence on coherin for relief of symptoms by multiple unsuccessful attempts to discontinue treatment over a long period of time. Diarrhea, in patients with ileitis symptoms, is effectively controlled by coherin therapy on a long-term basis.

Crohn Disease↗
PubMed1961

Primary Crohn's disease of the colon and rectum.

Crohn's disease of the large bowel has been increasingly recognized and this paper presents a clinical and pathological study of 45 patients in whom the disorder was confined entirely to the large intestine. The clinical and pathological factors are contrasted with those of 86 patients with regional ileitis and of 200 patients with ulcerative colitis. Compared with regional ileitis the disease occurred in an older age group, had a different sex distribution, and a higher incidence of perianal and rectovaginal fistulae. A high incidence of recurrent disease following surgical treatment, found in the patients with regional ileitis, was not found in the patients with primary Crohn's disease of the large intestine. The incidence of the disease relative to ulcerative colitis was approximately 6%. The disease had the same sex distribution as ulcerative colitis but occurred in an older age group. The disease was usually of gradual onset and continuous course, and periods of freedom lasting a month or more were uncommon. The patients came to surgery much earlier than patients with ulcerative colitis.

Colitis, Ulcerative↗
PubMed1994

Endoscopic study of the ileal papilla in a normal case and in patients under several pathological conditions.

The ileal protrusion into the lumen of the large intestine was studied in 9 patients (8 adults and 1 girl), 6 females and 3 males, all Brazilians and Caucasians. One of the patients resulted to have no disease, whereas in the others was confirmed the suspected diverticulosis, non specific ulcerative colitis, polyposis, regional ileitis or tuberculosis. In all cases the papillary and bilabial types of the termination of the ileum was documented by endoscopic photography, justifying the change of the expression "Bauhin's ileocecal valve" to that of "eminentia ilealis". Even in cases (one with regional ileitis and the other with tuberculosis) in which the disease altered the eminentia ilealis, it was possible to recognize the ileal papilla. Endoscopy confirmed direct, in vivo observations of ileal papilla, excluding the influence of the surgical procedure (incision and exteriorization in cases of cecostomy) in the morphological aspect of the normal eminentia ilealis.

Adult↗
PubMed1976

Fruit pit obstruction. "The propitious pit.".

Ingestion of fruit pit must be a frequent and innocuous phenomenon, judging from the expected frequency of such occurrences and the relative dearth of medical reports to the contrary. Reported here are four cases in which fruit pits of varied nature completed an otherwise incomplete intestinal obstruction. On of these was in the terminal ileum, with incomplete obstruction due to regional ileitis, in which the offending pit was seen radiologically but was not recognized as such. The other three were in the transverse colon, at the site of annular carcinomatous lesions. The completion of the obstruction by the fruit pits eventuated in earlier symptoms, diagnosis, and treatment. In one case, the fruit pits were multiple; in the remainder, they were single.

Aged↗
PubMed1989

Small bowel carcinoma in Crohn's disease. Distinguishing features and risk factors.

An 86-year-old woman who developed small bowel adenocarcinoma 40 years following in-continuity bypass of a 60-cm segment of regional ileitis represents the 22nd reported patient with this complication of bypassed Crohn's disease. Her case demonstrates several of the typical clinical features of such cancers: late recrudescence of disease following a 40-year period of relative quiescence; delayed diagnosis due to misinterpretation of the clinical picture (intestinal obstruction, abdominal mass, intraabdominal abscess, and fistula formation) as due to inflammatory bowel disease; and an exceedingly poor prognosis with rapid widespread local dissemination and death. Histologically, severe dysplasia was demonstrated both in close proximity to and at a distance from the lesion. The increasing number of case reports of adenocarcinoma arising at the site of long-standing Crohn's disease, many with dysplasia within areas of diseased bowel, is further evidence that Crohn's disease is a precancerous condition. Physicians must continue to search for methods of earlier diagnosis to improve the prognosis of small bowel carcinoma in Crohn's disease.

Adenocarcinoma↗
PubMed1988

Circumferential nodulocystic keratopathy. A case report.

An apparently unique type of corneal nodular keratopathy is presented. The keratopathy was characterized by large, circumferentially bilaterally located, cystic nodules just inside the limbus. No epithelial cell or collagenous degeneration nor evidence of chronic inflammatory process was found on histopathologic examination of a biopsy of a nodule. Proteinaceous material was present between the epithelial cell basement membrane and collagenous stroma. There was no antecedent history of keratitis or uveitis. The patient was known to have inflammatory bowel disease (regional ileitis) and rheumatoid arthritis with ankylosing spondylitis. However, the corneal lesions could not definitely be associated with any of these disorders. This case does not correspond with any previously described corneal disorders. We have termed it circumferential nodulocystic keratopathy, which best describes its clinical and histologic features.

Albumins↗
PubMed1983

Rectourethrocutaneous fistula in Crohn disease.

Fistulae from the gastrointestinal tract to the urinary tract are a well-known complication of Crohn disease. The majority of these are ileovesical. On rare occasion, patients with perianal complications of regional ileitis or granulomatous colitis may develop rectourethrocutaneous fistulae. The authors have encountered 2 such patients and add them to the 3 previously reported cases in the English literature. Retrograde urethrography and voiding cystourethrography established the diagnosis.

Adult↗
PubMed1979

The physiologic properties and therapeutic potential of coherin.

Coherin, a peptide isolated from the bovine neurohypophysis, has been shown to be an effective therapeutic agent in post-gastric surgery physiologic obstruction and regional ileitis. Of twenty-four patients with post-gastric surgery physiologic obstruction, coherin relieved symptoms in twenty-three, a 96 per cent efficacy rate. The efficacy of coherin with ileitis was based on the fact that ten of twenty-seven patients treated have required coherin on a continuing basis to stay functional. These patients have requested coherin treatment for an average of five years each, and have each on multiple occasions tried to discontinue coherin treatment with prompt return of symptoms and cessation of symptoms when coherin was reinstituted. All of the ileitis patients had previously failed to respond to standard and usual medical treatment.

Animals↗
PubMed1981

Pathogenesis of cholesterol gallstones.

The factors leading to cholesterol cholelithiasis are probably multiple. Although the secretion of bile supersaturated with cholesterol seems to be a common feature among all patients who form cholesterol stones, a variety of pathophysiologic events can produce an increase in lithogenicity. Dietary factors, particularly in the grossly obese, lead to an absolute increase in secretion of cholesterol into bile. Occasionally, excessive loss of the bile salt pool, for example with regional ileitis, may decrease the ability of bile salts to solubilize cholesterol. In many other, subtle alterations in the enterohepatic circulation of bile salts may adversely affect solubility by both decreasing the secretion of bile salts and increasing the secretion of cholesterol. Regardless of its cause, supersaturation of bile with cholesterol appears to be a prerequisite for gallstone formation. However, additional factors within the gallbladder, such as increased secretion of glycoprotein, increased absorption of fluids, infection, and stasis, appear to contribute to the formation of macroscopic stones.

Animals↗