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Refinements in mandibular reconstruction.

The new advances in the application of the prevascularized bone grafts, i.e., fibula and inner cortex iliac crest, have contributed a major advance in the field of mandibular reconstruction. Better understanding of rigid skeletal fixation and its ability during vascularized bone graft transfers further enhances flap survival and patient rehabilitation. Additional advances in techniques of osteointegration, TMJ reconstruction, and soft-tissue reconstruction have greatly augmented our ability for further refinements in this field.

Adult↗

Part II. Mandibular reconstruction: combined intra-oral and in vitro placement of osseointegrated implants into a free and vascularized bone graft.

A 28-year-old Hispanic girl underwent a complete mandibular reconstruction many years following full mandibulectomy for fibrous dysplasia. Because of infectious complications, both free cranial and microvascular iliac crest grafts were used. The patient had osseointegrated implants placed directly into the grafted mandible. Osseointegrated implants were also placed into a segment of free iliac crest bone, in vitro, and then grafted laterally onto the reconstructed mandible. Prosthetic reconstruction was then carried out to restore the patient to normal function, health, comfort, and esthetics.

Adult↗

[Mandibular reconstruction using an iliac crest free flap vascularized by the deep circumflex iliac vessels. A clinical study apropos of 30 cases].

Thirty cases of mandibular defects were reconstructed with a free iliac flap vascularised by the deep circumflex iliac vessels. Twenty five of these cases involved soft tissue damage with a defect of the mandible. The surgical procedure described by I. Taylor was used. Three anatomical variations of the pedicle were found. The features of the iliac bone are particularly suitable for mandibular reconstruction. The natural shape of the iliac bone does not require complex osteotomies and its healing capacity allows simple osteosynthesis. The thickness of the muscular pedicle, and thus the flap, is determined by the position of the lower edge of the skin components with respect to the iliac crest. This type of flap currently remains very useful in reconstruction of major mandibular and adjacent soft tissue destruction because of the very low incidence of failure (2 cases) and complications.

Adolescent↗

Interface radiation dosimetry in mandibular reconstruction.

When a beam of radiation crosses the interface between two substances, secondary electrons are generated. This results in enhancement of the absorbed dose of radiation roughly proportional to the difference in atomic numbers. Interfaces are created in reconstruction of the mandible with implantable trays containing hematopoietic bone marrow and cancellous bone chips. Radiation was measured in tissue-equivalent material surrounding mandibular tray implants of titanium, vitallium, stainless steel, and Dacron/polyetherurethane. The absorbed dose was enhanced by 29% to 36% adjacent to the metallic trays; 1% dose enhancement was noted adjacent to the Dacron/polyetherurethane tray. We conclude that, when radiation therapy is necessary following mandibular reconstruction, homogeneity of dose is maintained and local soft-tissue reactions to excessive irradiation may be avoided by using a nonmetallic tray.

Biocompatible Materials↗

Mandibular reconstruction with composite microvascular tissue transfer.

Microvascular free tissue transfer has provided a variety of methods of restoring vascularized bone and soft tissue to difficult defects created by tumor resection and trauma. Over 7 years, 26 patients have undergone 28 free flaps for mandibular reconstruction, 15 for primary squamous cell carcinoma of the floor of the mouth or tongue, 7 for recurrent tumor, and 6 for other reasons [lymphangioma (1), infection (1), gunshot wound (1), and osteoradionecrosis (3)]. Primary reconstruction was performed in 19 cases and secondary in 9. All repairs were composite flaps including 12 scapula, 5 radial forearm, 3 fibula, 2 serratus, and 6 deep circumflex iliac artery. Mandibular defects included the symphysis alone (7), symphysis and body (5), symphysis-body-ramus condyle (2), body or ramus (13), and bilateral body (1). Fourteen patients had received prior radiotherapy to adjuvant or curative doses. Eight received postoperative radiotherapy. All patients had initially successful vascularized reconstruction by clinical examination (28) and positive radionuclide scan (22 of 22). Bony stability was achieved in 25 of 26 patients and oral continence in 24 of 26. One complete flap loss occurred at 14 days. Complications of some degree developed in 22 patients including partial skin necrosis (3), orocutaneous fistula (3), plate exposure (1), donor site infection (3), fracture of reconstruction (1), and fracture of the radius (1). Microvascular transfer of bone and soft tissue allows a reliable reconstruction--despite previous radiotherapy, infection, foreign body, or surgery--in almost every situation in which mandible and soft tissue are absent. Bony union, a healed wound, and reasonable function and appearance are likely despite early fistula, skin loss, or metal plate or bone exposure.

Adult↗

Mandibular reconstruction using silicone: fifteen-year follow-up.

A patient is presented in whom a carved Dacron felt-covered silicone prosthesis was used to replace the mandible. Although not recommended as the procedure of choice for mandibular reconstruction, the prosthesis remains in place 15 years following implantation, the jaw appears and moves satisfactorily, and speech is within normal limits.

Follow-Up Studies↗

[Mandibular reconstruction. An historical overview].

In a historical review the most important technologies and auxiliary materials for lower jaw reconstruction are demonstrated and discussed. Personally developed implants for anatomical and functional reconstruction of the continuity and rigidity based on the latest experiences of bone surgery, are presented. The results of this development are demonstrated by several steps of mandibular reconstruction in a special clinical case. The discussion deals with the conclusions drawn from the historical review in comparison to our own clinical results.

Bone Nails↗

[A scapular osteo-cutaneous flap in mandibular reconstruction].

The authors report their experience with 6 cases involving the scapular T.O.L.V. technique described by Swartz et coll. They review the anatomy of the vascularisation of the flap together with the possible operative techniques. The 6 cases involved mandibular reconstruction following transmandibular bucco-pharyngectomy, either as first or second line surgery. In all cases the osteo-cutaneous flap gave a good quality reconstruction both in terms of oro-bucco-pharyngoplasty and in terms of repair of the horizontal portion of the mandible. The vascular pedicle was of satisfactory quality. Primary closure of the donor site was possible. No functional complications occurred at shoulder level. Combined reconstruction of the loss of bony and mucosal substance following this type of surgery considerably improves swallowing and phonation in these patients who previously had to undergo hemi-mandibulectomy.

Bone Transplantation↗

Conceptual considerations in mandibular reconstruction.

Microsurgical free tissue transfer allows for the immediate reconstruction of any composite mandibular defect. Most patients are candidates for reconstruction, and careful preoperative planning is an important key to success. Osteocutaneous free tissue transfer is currently the reconstructive modality of choice. The type of free flap used is determined by the requirements of the defect. Techniques such as condylar autotransplantation and osseointegrated implants are important adjuncts in achieving the best aesthetic and functional result.

Bone Plates↗

Mandibular reconstruction using electrically stimulated periosteum.

Electrically stimulated periosteum (ESP) grafting to a 12-year-old female patient who had had a segmental mandibulectomy in the anterior region following a diagnosis of Ewing's sarcoma was tried for the mandibular reconstruction. One year after the ESP transplantation, examination of the patient showed that fine, radio-opaque bone formation had occurred. The new technique consists of 1) electrical stimulation of the tibial periosteum with 20 microamperes for five weeks, and then 2) ESP transplantation into a titanium mesh tray placed in the mandibulectomized region. In the present report, these new procedures are detailed, and the process of calcification in the transplanted ESP is discussed.

Bone Transplantation↗

Fixation methods in mandibular reconstruction using fibula grafts: A comparative study into the relative strength of three different types of osteosynthesis

BACKGROUND: Bone staples made of a nickel titanium alloy exert dynamic compression, require little dissection, and may provide an alternative to conventional fixation in mandibular reconstruction with a free vascularized fibula graft. METHODS: To evaluate its stability relative to conventional methods of fixation with interosseous wires or miniplates, an in vitro model using beech dowels was developed. Torsional stiffness and strength and compression stiffness and strength were examined. RESULTS: The compression test results showed that maximum strength of interosseous wires is significantly less than memory staples, which in turn are significantly weaker than titanium miniplates. Miniplates are significantly the most rigid form of fixation. Torsional testing showed no significant difference in strength between staples and miniplates and only a marginal difference in elasticity. Interosseous wires show a rapid decrease of strength and rigidity during torsional stress. CONCLUSION: When considering interosseous wires the least and miniplates the most stable form of fixation by which bone healing can occur, memory staples can provide enough stability to ensure consolidation. Copyright 2000 John Wiley & Sons, Inc. Head Neck 23: 1-7, 2001.

Journal Article↗

Fixation methods in mandibular reconstruction using fibula grafts: a comparative study into the relative strength of three different types of osteosynthesis.

BACKGROUND: Bone staples made of a nickel titanium alloy exert dynamic compression, require little dissection, and may provide an alternative to conventional fixation in mandibular reconstruction with a free vascularized fibula graft. METHODS: To evaluate its stability relative to conventional methods of fixation with interosseous wires or miniplates, an in vitro model using beech dowels was developed. Torsional stiffness and strength and compression stiffness and strength were examined. RESULTS: The compression test results showed that maximum strength of interosseous wires is significantly less than memory staples, which in turn are significantly weaker than titanium miniplates. Miniplates are significantly the most rigid form of fixation. Torsional testing showed no significant difference in strength between staples and miniplates and only a marginal difference in elasticity. Interosseous wires show a rapid decrease of strength and rigidity during torsional stress. CONCLUSION: When considering interosseous wires the least and miniplates the most stable form of fixation by which bone healing can occur, memory staples can provide enough stability to ensure consolidation.

Bone Plates↗

Simultaneous maxillary and mandibular reconstruction with one free osteocutaneous flap.

The concept of immediate reconstruction of massive facial injury with rigid internal fixation and free-tissue transfer continues to evolve. This case is unique in that it is the first report of the following: (1) simultaneous combined maxillary and mandibular reconstruction with one vascularized bone graft and (2) immediate total maxillary reconstruction with vascularized fibular bone. The nasopharynx was closed with a tubed radial forearm flap. Reconstruction was staged over several days, with dissection/banking of flaps, grafts, recipient sites, and debridement as a preliminary stage.

Adult↗

Vertical distraction osteogenesis of fibula transplants for mandibular reconstruction--a preliminary study.

INTRODUCTION: When reconstructing the mandible after tumour resection with a fibular graft, the mandible is often vertically deficient, making placement of dental implants impossible. PATIENTS: Segmental vertical distraction of the reconstructed mandible was performed in nine patients following tumour surgery between February 1998 and 2001. Their age was 14-65 years (average 46.3); all underwent radiotherapy with a dose of up to 55.6 Gy prior to tumour resection. Mandibular discontinuity was repaired with a microvascular fibular bone graft. All grafts had a vertical bone deficit ranging from 9 to 12 mm when compared with the non-resected part of the mandibles. METHODS: All patients underwent segmental vertical distraction of the transplants. The distraction devices were applied intraorally. Distraction of 1.0 mm/day was performed using a Martin distractor (TRACK 1.5) followed by 12 weeks retention time. RESULTS: The increase of vertical bone height was stable and enabled placement of dental implants without any complications. CONCLUSION: Vertical distraction osteogenesis may become a common procedure in the treatment of alveolar ridge deficiency resulting from transplanting fibulae for mandibular reconstruction following tumour surgery.

Adolescent↗

[Osteomuscular serrato-costal free flap: application to mandibular reconstruction].

The serrato-costal free flap provides a large costal flap vascularized by a digitation of the serratus anterior muscle supplied by the dorsal thoracic artery. The flap is easy and rapid to raise with low morbidity. The repair obtained is functionally very satisfactory, but does not allow insertion of an implant. Six cases are reported. The indications of this technique of mandibular reconstruction are discussed.

Adult↗

Femoral nerve palsy after mandibular reconstruction with microvascular iliac flap: a complication under anticoagulation therapy.

Pharmacological prophylaxis and intervention are used extensively in head and neck reconstructions with microvascular flaps. There is no universally accepted protocol, but the microvascular surgery literature recommends intraoperative anticoagulation with heparin. Here is reported a case of iliacus haematoma with subsequent femoral nerve palsy after the harvest of a microvascular iliac flap for mandibular reconstruction in a patient who had been treated with heparin. The association between femoral nerve palsy and anticoagulant therapy has been well described. It remains unclear as to why the iliacus muscle is particularly vulnerable to intramuscular haemorrhage. Femoral nerve neuropathy is also an uncommon but recognized complication after abdominopelvic surgery. Iliacus haematoma secondary to microvascular surgery has not been previously reported. This case illustrates the need to be aware of this type of complication and its clinical manifestations for patients under anticoagulant therapy in the perioperative period during microvascular reconstructions.

Adult↗

The fate of osseointegrated implants in patients following oral cancer surgery and mandibular reconstruction.

BACKGROUND: The feasibility of implant treatment in patients after oral ablative tumor surgery and defect reconstruction has not yet been investigated in terms of the requisite high standards of success assessment. A report on this topic must address not only implant survival but implant health, bone response, soft tissue health, failure pattern, and time of failure, as well. METHODS: From June 1990 through December 1997, 90 patients received 320 dental implants after oral tumor resection and immediate soft tissue reconstruction. Included in the study were 45 patients with 162 implants loaded for at least 1 year. Regular follow-up for 6 years consisted of detailed medical history and evaluation of periodontal parameters. Out of this population, 10 vascularized iliac bone grafts for mandibular reconstruction containing loaded implants were selectively evaluated for bone loss. RESULTS: The assessment of pocket probing depths, plaque accumulation, bleeding disposition, implant mobility by means of the Periotest method applied to the restoration type, horizontal and vertical (peri-implant) bone loss according to x-ray findings, causes and time of implant loss, and subjective statements offered results comparable to those found in healthy subjects examined with periodontal success parameters. CONCLUSION: Prosthetic restoration of patients after oral ablative tumor surgery followed by hard and soft tissue reconstruction can be achieved with dental implants with similar long-term efficacy as found in healthy subjects adhering to internationally established requirements.

Adult↗