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Implant-retained mandibular overdentures with immediate loading. A retrospective multicenter study on 226 consecutive cases.

A multicenter retrospective study has been conducted on 226 patients necessitating an implant-supported overdenture in the lower jaw. The patients were provided with 904 osseointegrated implants inserted in the interforaminal area of the mental symphisis (4 implants per patient). 4 titanium implant systems were used: TPS and ITI screw implants (Straumann Institute, Waldenburg, Switzerland); Ha-Ti screw implants (Mathys Dental Implants, Bettlach, Switzerland); NLS screw implants (Friatec, Mannheim, Germany). Immediately after implant placement, a U-shaped gold bar was fabricated and implants were immediately loaded with an implant-retained overdenture. Out of 226 patients treated, 194 were followed from a minimum of 2 years to a maximum of 13 years, with a mean follow-up of 6.4 years, whereas 32 patients dropped out during follow-up. The overall failure rate of implants was 3.1% (24/776 implants), whereas the failure rate of bars was 1.5% (3/194 bars). Results from this study showed that the success rate of immediately loaded implants is similar to that obtained in the case of delayed loading, after osseointegration has taken place. In contrast, this method shortens dental rehabilitation times with relevant satisfaction for patients.

Adult↗

Long-term evaluation of single crystal sapphire implants as abutments in fixed prosthodontics.

49 patients participated in a prospective study of treatment of total or partial edentulism with fixed prosthodontics supported by Bioceram sapphire implants. 15 patients were treated for maxillary or mandibular edentulism, and 7 for a missing maxillary anterior tooth. The remaining 27 patients, with Applegate-Kennedy Class I-IV residual dentitions, were treated with fixed bridges supported by free-standing implants, or bridges supported by teeth and implants. Implant success, prosthesis stability, radiographic marginal bone level as well as parameters for peri-implant health were evaluated. The study began in 1982, and clinical treatment of the last patients was completed in 1988, i.e., a follow-up period ranging from 7 to 13 years. Of the patients treated for total mandibular edentulism, one implant fractured after 6 years in situ. The bone implant score (BIS) values for those implants were at the time for the bridge cementation 63.5 +/- 1.4 and at 1, 2, 3 and 5 year follow-ups 62.1 +/- 1.4, 61.9 +/- 1.5, 61.5 +/- 1.6, and 60.95 +/- 1.3, respectively. The success rate was 100%, 100% and 97.7% for the mandible at 3, 5 and 10 years, respectively. Of the 7 edentulous patients treated with maxillary fixed bridges, 6 implants in 1 patient had to be removed after 1 year in service. Another 2 patients lost all their implants, 6 each, after 36 months. 6 implants in the 4th patient did not fulfil the criteria for success and were rated as failures at the four year follow-up. The success rate was thus 58.1%, 44.2% and 44.2% for the maxilla at 3, 5 and 10 year follow-ups, respectively. Of the 7 patients in whom single missing teeth were replaced, 1 implant in the premolar region was lost during the 1st year post-operatively, but no other complications or changes in BIS were observed. Of the 27 patients treated for partial edentulism (56 implants total) 1 implant, of a 4-unit free standing maxillary bridge fractured after 6 years and was later replaced. There were no statistically significant differences in BIS changes for the implants when used as abutments for partial maxillary or mandibular edentulism. The cumulative success rates for the implants in the partially maxilla were 96.3, 92.6 and 92.6 at the 3, 5 and 10 years respectively and 100% in the mandible over the whole period.

Adult↗

A prospective evaluation of Frialoc implants with ball-abutments in the edentulous mandible: 1-year results.

Several surgical and prosthetic concepts for the treatment of patients with mandibular atrophy and related lower denture problems are proposed and described in the literature. The present study discusses and evaluates the use of a new single-stage implant and overdenture with ball-attachment for this purpose. This study evaluates the clinical performance of the implants and abutments and addresses surgical and prosthetic complications that were encountered. Eighteen fully edentulous patients received two, single-stage Frialoc implants (Friadent, Mannheim, Germany). The implants were left to osseointegrate for 3 months and were subsequently provided with ball-abutments and loaded through a mandibular overdenture. After 1-year of clinical service, two implants were lost, which accumulated to a 1-year survival rate of 93.9% (SE 4.2%). Patient satisfaction was high, and prosthetic complications and postinsertion maintenance were minimal. Three abutments loosened, one of which subsequently broke after 5 months of loading. Retightening of the attachment (gold matrix) was performed on seven occasions in four patients. Soft tissue response was excellent. Although minor hypertrophy of the peri-implant mucosa was observed, hardly any marginal bone loss between baseline and 1-year observations occurred. Short-term results indicate that mandibular implant overdenture treatment by means of two ball-abutments, using Frialoc implants and prosthetic components, leads to good clinical results, both from an objective and a subjective perspective.

Aged↗

Deformation at the implant interface to prosthetic superstructure: an interferometric approach.

Dental implants are deformed by masticatory forces. These deformations may affect the implant, the prosthetic superstructure or, in particular, the interfaces between the implant and the superstructure. The resulting changes in the geometrical relationships may lead to gap formation in this region. The objective of the present pilot study was to present an interferometric method for the direct recording and quantitative three-dimensional analysis of load-induced dynamic implant deformation. Three implant screws of 4.1 mm diameter were loaded using a piezoelectric device. The results showed that the screws itself exhibited a homogeneous deformation pattern, whereas implants with screw-retained superstructures demonstrated dislocations of the crown and resulting gap formations (0.27 +/- 0.37 microm--mean +/- SD; max: 0.82 microm). The results supported the hypothesis that the high precision of prefabricated abutments is adversely affected by dynamic deformations under functional loading.

Analysis of Variance↗

Dynamic fatigue resistance of implant-abutment junction in an internally notched morse-taper oral implant: influence of abutment design.

PURPOSE: To compare dynamic fatigue resistance of one- and two-piece abutments connected to internally notched morse-taper oral implants. MATERIAL AND METHODS: Sixteen synOcta ITI implants were tightened into two metal models. SynOcta abutments for cement-retained restorations and solid abutments were divided into two equal groups and were torque-tightened into the implants. Each implant received a cement-retained crown. Cyclic dynamic axial and lateral peak loads of 75+/-5 N were applied on the implants for a duty of 500,000 cycles at 0.5 Hz, and at an angle of 20 degrees. Prior to the experiments and at each 100,000 cycles of loading, periotest values (PTVs) were measured. Removal torque values (RTVs) of the abutments were also measured with a custom-made torque device at the termination of the experiment. RESULTS: All abutments and implants were clinically immobile and without any signs of mechanical failure. The final PTVs for both abutments were similar and the difference between groups was insignificant (P>0.05). The RTVs of solid abutments were significantly higher than synOcta abutments (P<0.05). CONCLUSION: Predictable long-term clinical results can be achieved with solid abutments and synOcta abutments for cement-retained restorations. Solid abutments possess higher removal torque resistance than synOcta abutments when connected to synOcta ITI implants.

Cementation↗

A controlled clinical trial of implant-retained mandibular overdentures: 10 years' results of clinical aspects and aftercare of IMZ implants and Brånemark implants.

The aim of this prospective randomized controlled clinical trial was to evaluate the clinical outcomes and prosthetic aftercare of edentulous patients with a mandibular overdenture retained by two IMZ implants or two Brånemark implants during a 10-year period. Patients were allocated to the IMZ group (n=29) or the Brånemark group (n=32) by a computerized balancing method. In the IMZ group, four implants were lost during the 10-year follow-up (survival rate: 93%). In the Brånemark group, nine implants were lost (survival rate: 86%). All patients were re-operated successfully. Multiple prosthetic revisions were necessary in both groups; especially the precision attachment system in the overdenture (23% of the total number of revisions) and the denture base and teeth (26% of the total number of revisions) were subject to frequent fracture. From this study, it can be concluded that both the IMZ implant and the Brånemark implant systems supporting an overdenture are functioning well after 10 years of follow-up. There are no indications of a worsening of clinical or radiographical state after 10 years.

Alveolar Bone Loss↗

Resonance frequency analysis of implants subjected to immediate or early functional occlusal loading. Successful vs. failing implants.

OBJECTIVES: The objective of this study was to analyze the development of implant stability by repeated resonance frequency analysis (RFA) measurements during 1 year in 23 patients treated according to an immediate/early-loading protocol. The objective was also to evaluate the possible differences between failing and successful implants. MATERIAL AND METHODS: Eighty-one Brånemark System implants were placed in 23 patients for immediate/early-occlusal loading in all jaw regions. Thirty of the implants were placed in extraction sockets and 62 were subjected to GBR procedures. Apart from clinical and radiographic examinations, the patients were followed with RFA at placement, prosthesis connection and after 1-3, 6 and 12 months. Statistical analyses were carried out to study the possible differences between implants that failed during the study period and implants that remained successful. RESULTS: Nine implants failed (11.2%) during the 1 year of loading. RFA showed a distinct different pattern between the implants that remained stable and the implants that were lost. The implants that failed during the course of the study showed a significantly lower stability already after 1 month. CONCLUSION: Within the limitations of this study, it is concluded that failing implants show a continuous decrease of stability until failure. Low RFA levels after 1 and 2 months seem to indicate an increased risk for future failure. This information may be used to avoid implant failure in the future by unloading implants with decreasing degree of stability with time as diagnosed with the RFA technique.

Dental Implantation, Endosseous↗

Efficacy of dental implants placed into fibula-free flaps for orofacial reconstruction.

OBJECTIVES: The transfer of the osseofasciocutaneus fibula-free flap has become a routine procedure in the reconstruction of comprehensive orofacial defects. Besides its length, major advantages of the fibula-free flap include the trigonal diameter of the fibular bone, which usually allows the placement of dental implants. PATIENTS AND METHODS: In a prospective study, 16 consecutive patients who received free fibula grafts and in total 51 dental implants between 1999 and 2001 were examined. All implants were inserted secondary after bone grafting and loaded after 3 months of submerged healing. The observation period extended 2.5 years on average. The implant success was controlled clinically, radiographically and by resonance frequency analysis. RESULTS: One implant that was located at the interface between the fibula graft and the mandible was lost due to dehiscence and local infection during the healing period. In two other patients, one implant had to remain unexposed as 'sleeper' due to an unfavourable soft tissue situation. The success rate calculated by Kaplan-Meier analysis was 96.1% after an observation period of 1400 days. Resonance frequency analysis (ISQ-values) revealed significant differences related to the orientation (vestibulo-oral/mesio-distal; vo/md) of the transducer unit (P < 0.01). In general, a high primary stability for implants placed in free fibula grafts could be achieved (vo/md 66/74.1), which on average increased slightly during the healing period (vo/md 67.4/75.4) and within 12 month of functional loading (vo/md 72.1/79.9). Additional augmentation with iliac bone grafts or reconstructions with a double barred fibula resulted in an improved reconstruction of the alveolar process, thus allowing superior individual implant positions or angulations, but no elevation of the ISQ-values. CONCLUSION: The fibula-free flap provides a consistent bone graft that allows a reliable and predictable restoration with dental implants.

Adult↗

Implant stability measurement of delayed and immediately loaded implants during healing.

The purpose of the present study was (1) to measure the primary stability of ITI implants placed in both jaws and determine the factors that affect the implant stability quotient (ISQ) determined by the resonance frequency method and (2) to monitor implant stability during the first 3 months of healing and evaluate any difference between immediately loaded (IL) implants and standard delayed loaded (DL) implants. The IL and DL groups consisted of 18 patients/63 implants and 18 patients/43 implants. IL implants were loaded after 2 days; DL implants were left to heal according to the one-stage procedure. The ISQ was recorded with an Osstell apparatus (Integration Diagnostics AB, Gothenburg, Sweden) at implant placement, after 1, 2, 4, 6, 8, 10 and 12 weeks. Primary stability was affected by the jaw and the bone type. The ISQ was higher in the mandible (59.8+/-6.7) than the maxilla (55.0+/-6.8). The ISQ was significantly higher in type I bone (62.8+/-7.2) than in type III bone (56.0+/-7.8). The implant position, implant length, implant diameter and implant deepening (esthetic plus implants) did not affect primary stability. After 3 months, the gain in stability was higher in the mandible than in the maxilla. The influence of bone type was leveled off and bone quality did not affect implant stability. The resonance-frequency analysis method did not reveal any difference in implant stability between the IL and DL implants over the healing period. Implant stability remained constant or increased slightly during the first 4-6 weeks and then increased more markedly. One DL and IL implant failed; both were 8 mm long placed in type III bone. At the 1-year control, the survival rate of the IL and the DL implants was 98.4% and 97.7%, respectively. This study showed no difference in implant stability between the IL and DL procedures over the first 3 months. IL short-span bridges placed in the posterior region and full arch rehabilitation of the maxilla with ITI sandblasted-and-etched implants were highly predictable.

Acid Etching, Dental↗

Predicting osseointegration by means of implant primary stability.

The purpose of the present clinical study was (1) to evaluate the Osstell as a diagnostic tool capable of differentiating between stable and mobile ITI implants, (2) to evaluate a cut-off threshold implant stability quotient (ISQ) value obtained at implant placement (ISQitv) that might be predictive of osseointegration, (3) to compare the predictive ISQitv of immediately loaded (IL) implants and implants loaded after 3 months (DL). Two patient groups were enrolled, 18 patients received 63 IL implants and 18 patients were treated with 43 DL implants. The ISQ was recorded at implant placement, after 1, 2, 4, 6, 8, 10 and 12 weeks. All implants passed the 1-year loading control. Two implants failed, one DL implant with ISQ at placement (ISQi) of 48 and one IL implant with ISQi of 53. The resonance-frequency analysis (RFA) method was not a reliable diagnostic tool to identify mobile implants. However, implant stability could be reliably determined for implants displaying an ISQ> or =47. After 1 year of loading, all DL implants with an ISQi> or =49 and all IL implants with an ISQi> or =54 achieved and maintained osseointegration. By the end of 3 months, implants with ISQi<60 had an increase of stability. Implants with ISQi 60-69 had their stability decrease during 8 weeks before returning to their initial values. Implants with ISQ>69 had their stability decrease during the first 4 weeks before remaining stable. Although preliminary, these data might orient the practitioner to choose among various loading protocols and to selectively monitor implants during the healing phase.

Dental Abutments↗

Early loading of non-submerged titanium implants with a sandblasted and acid-etched surface. 5-year results of a prospective study in partially edentulous patients.

OBJECTIVES: The aim of this prospective cohort study was to evaluate the success rate of titanium screw-type implants with the sandblasted and acid-etched (SLA) surface loaded early, after 6 weeks of healing. MATERIAL AND METHODS: A total of 104 implants were inserted into posterior sites of 51 partially edentulous patients exhibiting bone densities of class I-III. After a healing period of 6 weeks, all implants were functionally loaded with cemented crowns or fixed partial dentures. The patients were recalled at 3, 12, 24, 36, 48 and 60 months for clinical and radiographic examination. RESULTS: One implant failed to integrate during healing, and three implants were lost to follow-up and were considered drop-outs. The remaining 100 implants showed favorable clinical and radiographic findings at the 5-year examination. The peri-implant soft tissues were stable over time; the mean probing depths and mean attachment levels did not change during the follow-up period. None of the radiographs exhibited signs of continuous peri-implant radiolucency, which confirmed ankylotic stability for all 100 implants. The measurement of the bone crest levels (DIB values) indicated stability as well. Based on strict success criteria, all 100 implants were considered successfully integrated, resulting in a 5-year success rate of 99%. CONCLUSION: This prospective study using an early loading protocol with 6 weeks of healing demonstrated that titanium implants with the SLA surface can achieve and maintain successful tissue integration with high predictability for at least 5 years of follow-up in selected patients and sites.

Crowns↗

Bone density and primary stability in implant therapy.

INTRODUCTION: To improve patient comfort, deviations from the very successful standard osseointegration protocol are being developed. To keep implant failure rates as low as possible, the most perfect treatment planning and a good patient selection are extremely important. Because bone density plays an important role in implant outcome, known relations of bone density could improve treatment planning. MATERIAL AND METHODS: A Pubmed search revealed 66 manuscripts investigating and discussing bone density of human jawbone whether or not related to implant stability or outcome. Forty-five of these will be discussed in this review. RESULTS AND DISCUSSION: Many pre-operative methods of jawbone density assessment are available. Most of those techniques correlate well with one another. Some are more elaborate to use in clinical practice. Primary stability measurements show significant correlations with different bone densities and also with implant outcome; however, not many studies investigate both at the same time. CONCLUSION: To investigate the outcome of adaptation methods of the surgical protocol with regard to the jawbone density, an objective pre-surgical determination of bone density is necessary.

Bone Density↗

Biomechanical aspects of oral implants. Consensus report of Working Group 1.

The method used by the working group was an iterative process based upon a structured review of the relevant literature by a group of reporters. The review papers were circulated to the members of the group before the conference and formed the basis for subsequent discussions. Each paper was subject to detailed collective analysis and subsequently modified on the basis of the panel's discussions and referenced to additional relevant literature where appropriate. The group assessed the levels of evidence for the statements made in the supporting documentation and recognized that it was necessary to adopt a compromise between acceptance of the lowest level, resulting in the largest body of material, and the highest level, which, in some cases, produced little evidence. While this approach does not represent endorsement of lower evidence levels per se, it was designed to provide conclusions of clinical utility within the existing knowledge base. The consensus statements were prepared after a detailed consideration of the papers submitted to the workshop by the working group. The papers were scrutinized, amended and approved by the group. The basis of each paper is described in the section on 'search strategy' and defines the parameters within which the consensus statements were prepared.

Biomechanical Phenomena↗

Validity and clinical significance of biomechanical testing of implant/bone interface.

PURPOSE: The aim of this paper was to review the clinical literature on the Resonance frequency analysis (RFA) and Periotest techniques in order to assess the validity and prognostic value of each technique to detect implants at risk for failure. MATERIAL AND METHODS: A search was made using the PubMed database to find clinical studies using the RFA and/or Periotest techniques. RESULTS: A limited number of clinical reports were found. No randomized-controlled clinical trials or prospective cohort studies could be found for validity testing of the techniques. Consequently, only a narrative review was prepared to cover general aspects of the techniques, factors influencing measurements and the clinical relevance of the techniques. CONCLUSIONS: Factors such as bone density, upper or lower jaw, abutment length and supracrestal implant length seem to influence both RFA and Periotest measurements. Data suggest that high RFA and low Periotest values indicate successfully integrated implants and that low/decreasing RFA and high/increasing Periotest values may be signs of ongoing disintegration and/or marginal bone loss. However, single readings using any of the techniques are of limited clinical value. The prognostic value of the RFA and Periotest techniques in predicting loss of implant stability has yet to be established in prospective clinical studies.

Bone Density↗

Periodontal parameters around porous-coated dental implants after 3 to 4 years supporting overdentures.

In this study, an assessment using modified periodontal indices was done on a group of 48 fully edentulous patients who had each been treated with 3 porous-coated (EndoPore) dental implants and a mandibular overdenture. Parameters assessed included plaque index (PI), sulcular bleeding index (SBI), pocket probing depth (PD), probing attachment level (PAL) and mobility (M) using a Periotest device. At the time of the assessment, all of the patients had passed 3 years of continuous function while 26 had passed 4 years. Approximately 50% of implant surfaces were plaque-free while 79% of surfaces showed no bleeding upon probing. There was no correlation between PI and SBI. The mean PD was 3.1 mm with 64% of sites < or = 3.5 mm. Mobility measurements taken with the Periotest device gave a mean PTV of (-4.35) with 96% of measurements (-0.5). No significant correlations were found between mobility and either PAL or implant length.

Analysis of Variance↗

Mandibular overdentures supported by two Brånemark, IMZ or ITI implants: a 5-year prospective study.

OBJECTIVES: The aim of this prospective comparative study was to evaluate the survival rate and the condition of the peri-implant tissues of the IMZ implant system (two-stage cylindertype), the Brånemark implant system (two-stage screwtype) and the ITI implant system (one-stage screwtype) supporting a mandibular overdenture during a 5-year follow-up period. MATERIAL AND METHODS: Three groups of 30 edentulous patients were treated with two endosseous implants in the interforaminal region of the mandible. Clinical and radiographic parameters were evaluated immediately after completion of the prosthetic treatment and after 1, 2, 3, 4 and 5 years of functional loading. RESULTS: The five-year survival rate is 98.3% for the IMZ group, 98.3% for the Brå group and 100% for the ITI group. Mean scores on indices for plaque, calculus, gingiva and bleeding were very low at all evaluation periods. Mean marginal bone loss over a period of 5 years, was 1.4 mm for the IMZ group, 0.7 mm for the Brå group and 0.9 mm for the ITI group. CONCLUSION: It is concluded that two implants placed in the interforaminal region, connected with a bar, supply a proper base for the support of a mandibular overdenture in the edentulous patient. After 5 years no clinically relevant and statistically significant radiographic changes had developed between the three implant systems.

Alveolar Bone Loss↗

Measuring patient satisfaction with mandibular prostheses.

OBJECTIVES: Previous research has shown that patients' evaluations of their prostheses correlate poorly with the clinicians' assessments, as well as with intraoral anatomic factors. It has been recommended that researchers conduct more studies that use patient satisfaction as the primary outcome measure in treatment evaluation and that more attention be paid to understanding exactly what measures of patient satisfaction represent. In this study, the relationship between patients' ratings of general satisfaction and their perceptions of different aspects of mandibular prostheses is investigated. METHODS: One hundred and twenty subjects applied to participate in a randomized controlled clinical trial comparing two types of mandibular prostheses: conventional dentures and implant prostheses. At baseline, they were asked to rate on 100 mm visual analog scales (VAS) factors that edentulous patients indicated were important to them. These included comfort, ability to chew, stability, esthetics, ability to speak and ease of cleaning of their conventional dentures. Subjects were also asked to rate their general satisfaction with their dentures. In addition, they selected the one quality of their denture that they considered to be most important. RESULTS: Multiple regression methods revealed that gender, as well as patients' ratings of comfort, stability, esthetics, ability to chew and ability to speak with their prostheses contributed significantly to general satisfaction (F<0.0001). Furthermore, 89% of the variation in ratings of general satisfaction was explained by these factors. In addition, patients who considered ability to chew as the most important factor associated with their dentures rated their general satisfaction significantly higher than the other subjects (P=0.0003). CONCLUSION: Patient satisfaction with conventional dental prostheses is highly dependent on gender, and the appearance and functionality of the appliance. The combined effect of these factors explained most of the variation in the satisfaction ratings.

Adult↗

Brånemark Novum: a new treatment concept for rehabilitation of the edentulous mandible. Preliminary results from a prospective clinical follow-up study.

BACKGROUND: Brånemark fixtures were originally prescribed to be placed in two surgical stages. During the past years, reports on the placement of machined titanium implants in a one-stage procedure have been published, and the results have been encouraging. Recently there has been considerable interest in early or immediate loading. PURPOSE: The purpose of this article is to report the preliminary clinical results of a new method for implant treatment of the edentulous mandible. The new protocol involves prefabricated components and surgical guides, elimination of the prosthetic impression procedure and attachment of the permanent fixed bridge on the day of implant placement. METHODS: Fifty patients (26 males, 24 females) received 150 Brånemark Novum implants and were followed from 6 months to 3 years after implant placement. Bone width and height were determined preoperatively with the use of radiographs. The jaw was reduced in height to accommodate three special 5-mm wide implants. Precise implant positioning was accomplished with special drilling templates. Drill guides were placed over the drilling templates during site preparation using a series of specially designed drills. After the mucosa had been sutured back into position, a prefabricated titanium lower bar was connected with titanium screws to the transmucosal fixture. Another titanium bar was then attached by the prosthodontist, and a bite registration was performed. The bridge was attached to the upper bar. The permanent reconstruction was provided to the patient later the same day. RESULTS: Three implants were lost to follow-up and three failed, resulting in an overall survival rate of 98%. One prosthesis failed, leaving a prosthetic survival rate of 98%. The average treatment time was approximately 7 hours. At the baseline examination, the marginal bone level was 0.72 mm below the reference point. The average marginal bone loss was 0.2 mm per year and 0.26 mm between the 3-month and 1-year control visits. The accumulated mean bone loss, including baseline, was -1.25 mm. A patient questionnaire demonstrated that 94% of the patients did not experience any discomfort during treatment and all patients would recommend the procedure to others. CONCLUSION: The results of this study indicate that the precise surgical and prosthetic protocol allows successful prosthetic rehabilitation of mandibular edentulism and that the permanent reconstruction can be provided to the patient on the day of fixture surgery.

Aged↗