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Reliability of in vivo volume measures of hippocampus and other brain structures using MRI.

Volume reductions of the hippocampus are associated with Alzheimer's disease, schizophrenia, and epilepsy. We used clinically available MRI methods (2D acquisition; inversion recovery and calculated T2 images; 3 mm contiguous slices) that optimize image contrast, quality, and resolution and standardized positioning protocols to maximize the in vivo accuracy (test-retest reliability) of brain volume measurements in volunteers who were scanned two or three times. Volunteers were scanned in the same MRI instrument (intrascanner reliability) as well as in two different instruments (interscanner reliability). A single rater obtained brain volume measures of seven contiguous slices centered on the anterior commissure. The in vivo intrascanner reliability for measures of anterior hippocampus and ventricular volumes was very good, with reliability coefficients [intraclass r (rxx)] ranging between .855 and .997, and a median coefficient of variation (CV) of 6.4%. Reliability was good for amygdala (rxx of .740 and .764) and for total frontal and temporal lobe volumes and white matter volume measures (rxx ranging between .640 and .823, median coefficient of variation was 3.2%). Overall, interscanner reliability was also good. We discuss the implications of our results relative to the possible clinical utility of hippocampal quantification and the feasibility of prospective studies aimed at quantifying progressive neurodegeneration.

Adult↗

Psychological measures: reliability in the assessment of stroke patients.

OBJECTIVE: To determine whether acute stroke patients can give reliable responses to standardized psychological measures. DESIGN: Survey design with retrospective review of Neurobehavioral Cognitive Status Examination (NCSE) scores. SETTING: A rehabilitation hospital in Philadelphia. PATIENTS: 106 consecutive admissions to stroke services at a rehabilitation hospital were evaluated according to the following inclusion criteria: Patients at least 65 years of age, English speaking, having a documented history of cerebrovascular accident (CVA), possession of receptive speech comprehension, and the ability to maintain attention adequate for participation in the study interview. Of the 47 eligible for participation, 10 patients refused participation and 13 were discharged before the interview could be completed. Thus 24 patients were interviewed, with one patient unable to complete the second half of the interview. MAIN OUTCOME MEASURES: In phase 1, the patient's performance on a structured interview (including the Multidimensional Health Locus of Control Scales (MHLC), Life Orientation Test (LOT), and Center for Epidemiological Studies Depression Scale (CES-D) scales) produced a Total Reliability Score, indicating the overall reliability of the patient's responses. In phase 2, NCSE scores were examined (retrospectively) for their ability to predict the patient's Total Reliability Score on the structured interview. RESULTS: Using Total Reliability Scores, 9 patients were categorized as "passing," 9 were categorized as "uncertain," and 5 were categorized as "failing" the interview. The NCSE was predictive for individuals who had a very low likelihood of being able to respond consistently. The NCSE failed to identify which individuals would respond in a reliable fashion. CONCLUSIONS: It is both possible and important to assess response reliability when using psychological measures soon after stroke. Future research will need to document other potential predictors of interview performance, including combinations of NCSE subscales.

Aged↗

Cumulative trauma disorders in the upper extremities: reliability of the postural and repetitive risk-factors index.

OBJECTIVE: This study addresses test-retest reliability of the Postural and Repetitive Risk-Factors Index (PRRI) for work-related upper body injuries. This assessment was developed by the present authors. DESIGN: A repeated measures design was used to assess the test-retest reliability of a videotaped work-site assessment of subjects' movements. SUBJECTS: Ten heavy users of video display terminals (VDTs) from a local banking industry participated in the study. SETTING: The 10 subjects' movements were videotaped for 2 hours on each of 2 separate days, while working on-site at their VDTs. MAIN OUTCOME MEASURE: The videotaped assessment, which utilized known postural risk factors for developing musculoskeletal disorder, pain, and discomfort in heavy VDT users (ie, repetitiveness, awkward and static postures, and contraction time), was called the PRRI. The videotaped movement assessments were subsequently analyzed in 15-minute sessions (five sessions per 2-hour videotape, which produced a total of 10 sessions over the 2 testing days), and each session was chosen randomly from the videotape. The subjects' movements were given a postural risk score according to the criteria in the PRRI. Each subject was therefore tested a total of 10 times (ie, 10 sessions), over two days. The maximum PRRI score for both sides of the body was 216 points. RESULTS: Reliability coefficients (RCs) for the PRRI scores were calculated, and the reliability of any one session met the minimum criterion for excellent reliability, which was .75. A two-way analysis of variance (ANOVA) confirmed that there was no statistically significant difference between sessions (p < .05). Calculations using the standard error of measurement (SEM) indicated that an individual tested once, on one day and with a PRRI score of 25, required a change of at least 8 points in order to be confident that a true change in score had occurred. The significant results from the reliability tests indicated that the PRRI was a reliable measurement tool that could be used by occupational health practitioners on the job site.

Adult↗

The Arm Motor Ability Test: reliability, validity, and sensitivity to change of an instrument for assessing disabilities in activities of daily living.

OBJECTIVE: To continue and expand determination of the reliability, validity, and sensitivity to change of the Arm Motor Ability Test (AMAT), an instrument for assessing deficits in activities of daily living (ADL). DESIGN: The AMAT was administered twice to patients, with an interest interval of either 1 or 2 weeks, by one of two examiners assigned to patients in counterbalanced order. Patients' interest intervals and scores on the arm portion of the Motricity Index was unknown to the raters. SETTING: A referral inpatient neurological rehabilitation center. PATIENTS: Thirty-three subacute stroke inpatients with moderate to mild upper extremity motor deficit: median Motricity-Index-Arm score = 89, median chronicity = 43d, median age = 66yr; 12 were women. MAIN OUTCOME MEASURE AND RESULTS: The AMAT was developed in 1987, and interrater reliabilities at that time were found to range from .95 to .99. The present values for interrater reliability (2 scales) from videotaped test performance were: kappas = .68 to .77. Spearman correlations = .97 to .99. For performance time, interscorer reliability from videotaped test performance was .99. Homogeneities for the three AMAT measures for the total sample (Cronbach's alpha and split-half reliability) were .93 to .99. The test-retest reliabilities for the total sample were .93 to .99. The correlations to the Motricity-Index-Arm score were .45 to .61. The AMAT detected the difference in change occurring as a result of the passage of 1 versus 2 weeks in these subacute inpatients, presumably as a result of intensive therapy and/or spontaneous recovery, confirming the results of an earlier intervention study. CONCLUSION: The AMAT is an instrument with high interrater reliability, internal consistency, and sensitivity to change, as well as having satisfactory concurrent validity.

Activities of Daily Living↗

High internight reliability of computer-measured NREM delta, sigma, and beta: biological implications.

BACKGROUND: Computer analysis of the sleep electroencephalogram (EEG) waveforms is widely employed, but there have been no systematic studies of its reliability. METHODS: The most commonly used computer methods are power spectral analysis with the fast-Fourier transform (FFT) and period amplitude analysis (PAA) with zero cross or zero first derivative half-wave measurement. We applied all three computer methods to the digitized EEG of 16 normal subjects who underwent 5 consecutive nights of baseline (placebo) recording. We evaluated the internight reliability of three non-rapid eye movement (NREM) frequency bands of special importance to sleep research: delta (0.3-3 Hz), sigma (12-15 Hz), and beta (15-23 Hz). RESULTS: Both FFT and the two methods of PAA gave excellent internight reliability for delta and sigma. Even a single night of recording correlated highly (r >.9) with the 5-night mean. Beta reliability was lower but still highly significant for both the PAA and the FFT measures. CONCLUSIONS: Computer-analyzed sleep EEG data are highly reliable. Period amplitude methods demonstrate that wave incidence and period as well as amplitude are reliable, indicating that the reliability of composite measures (FFT power, PAA integrated amplitude) is not solely based on individual differences in EEG amplitude. The high internight stability of NREM delta indicates that it possesses traitlike characteristics and is relatively independent of day-to-day variations in state.

Adult↗

A multirater validation study to assess the reliability of acne lesion counting.

BACKGROUND: Despite widespread use of acne lesion counting, little has been published on its reliability, particularly for multiple raters. OBJECTIVE: Our purpose was to assess reliability of acne lesion counting with the use of a five-segment facial template. METHODS: After training, 12 raters each evaluated 12 patients in randomized order, in the morning and again in the afternoon, and recorded counts for different types of lesions on a five-segment facial template. RESULTS: Individual raters could reproduce their total lesion counts (reliability estimates, 0.81 to 0.97). Variability between raters was high, and overall reliability estimated across raters was 0.61. For a subgroup of commonly trained raters, overall reliability was higher (0.80). CONCLUSION: The reliability of acne lesion counting is excellent when performed by the same trained rater over time. The high variability between raters appears to be reduced by standardized training. Because fewer lesions are counted with less variation, use of a template may have contributed to the high within-rater reliability.

Acne Vulgaris↗

Reliability and accuracy of different sensors of a flexible electrogoniometer.

OBJECTIVE: To describe a gauging device for electrogoniometer sensors and to evaluate the reliability and accuracy of different sensors including two similar sensors. DESIGN: Repeated measurement design for reliability. BACKGROUND: Despite being considered reliable equipment, several aspects of electrogoniometer reliability and accuracy have not been reported so far. METHOD: Five repeated measurements of each electrogoniometer sensor were performed in 1 degrees increments, during the whole uniplanar amplitudes of flexion, extension, lateral deviations and rotational movements, totaling 6380 measurements. RESULTS: Values from the coefficient of variation and mean square error, respectively indicated that the reliability and accuracy of the sensors varied between sensors and movements, with goniometers being more reliable and accurate than torsiometers. A significant difference between identical sensors was identified. CONCLUSIONS: No similar pattern of variation was found between the sensors evaluated, indicating that every sensor should be tested for its reliability and accuracy when highly precise measurements are needed, and particularly when bilateral limbs are being compared. RELEVANCE: Research on movement recordings demands precise methodology for quantifying angular variations.

Calibration↗

[Reliability of a questionnaire on smoking to evaluate prevalence, knowledge and attitudes of medical students].

OBJECTIVE: To evaluate the reliability and reproducibility of results obtained from a questionnaire on the smoking habits of medical students. METHOD: A questionnaire with 30 variables was designed to measure three main parameters: prevalence, knowledge and attitudes toward smoking. First-year medical students at the University of Zaragoza (1997-98 academic year) were asked to fill in the questionnaire, and a code was assigned to each individual respondent. A test-retest method was then used to assess reliability: the same questionnaire was answered by the subjects after a period of time had elapsed. The Kappa coefficient was calculated to measure agreement. RESULTS: The questionnaire was filled in by 181 students at registration and 7 weeks later by 43 students. The first- and second-time questionnaires for 35 individuals were matched by codes. Reliability was good for most variables related to the main characteristics of smoking (such as prevalence, number of cigarettes smoked daily and consonance-dissonance). Reliability was acceptable for most variables related to knowledge but was low for 3 items. Reliability was acceptable for half the items related to attitudes and low for half. CONCLUSIONS: The questionnaire has a generally good level of reliability, with regard to reproducibility, or the likelihood that an individual will respond to an item in the same way at two different times. Some variables that measure attitudes toward smoking, however, are less reliable. Results obtained for those items should therefore be interpreted cautiously.

Adult↗

Dissection and weighing of accessory sex glands after formalin fixation, and a 5-day assay using young mature rats are reliable and feasible in the Hershberger assay.

The rodent Hershberger assay has been used predominantly by the pharmaceutical industry to evaluate androgenic and antiandrogenic chemicals for potential therapeutic use. However, this assay has not yet been formally validated and standardized for use in toxicology testing. There are many variations in the protocol used for this assay. The weight of androgen-dependent tissues is a definitive endpoint in the Hershberger assay. To find out the reliable assay protocol with feasibility, although many possible factors may affect assay reliability, the present study consist of a series of three separate experiments focused on method of dissection and weighing of accessory sex glands (ASGs: ventral and dorso-lateral prostate, seminal vesicles together with coagulating glands, and Cowper's glands), animal age and number of doses. Furthermore, male pubertal assay, an alternative to the Hershberger assay, was also examined its reliability. Experiment 1 explored whether reliably accurate ASG weights can be obtained after formalin fixation. The ASGs were collected from castrated male rats (11 weeks of age) treated daily with corn oil, or testosterone propionate (TP, 0.25 mg/kg/day, s.c.) and p,p'-DDE (0 or 100 mg/kg/day, p.o.) for 5 days. One day after the final treatment, the ASGs were removed carefully and weighed separately, and then fixed overnight in a 10% neutral-buffered formalin and weighed again. After that, the tissues were dried overnight in an oven and weighed again. A high correlation between fresh and fixed tissue weights, and a high correlation between fixed and dried tissue weights were noted. The changes in the tissue weight due to fixation were marginal and were proportional to the fresh weights of the individual tissue. Standard deviation of the fixed tissue weight in each group and the magnitude of responses to TP or p,p'-DDE in fixed tissues were equivalent to those in fresh or dried tissues. These findings indicate that formalin fixation does not interfere with interpretation of assay results, and this procedure was used in the subsequent experiments. Experiments 2 and 3 explored whether animal age or treatment duration altered assay sensitivity. In Experiment 2, antiandrogenic effect of p,p'-DDE (100 mg/kg/day) was detected after 5-and 10-day treatment irrespective of animal age (7 vs 11 weeks). In Experiment 3, antiandrogenic effects of flutamide (1 and 10 mg/kg/day) and p,p'-DDE (10 and 100 mg/kg/day) were compared between two different protocols, the 10-day assay using peripubertal rats and the 5-day assay using young mature rats. Results demonstrated that both protocols could significantly detect antiandrogenic effects of flutamide and p,p'-DDE. These findings demonstrate that (1) dissection and weighing of ASGs after formalin fixation is reliable in the Hershberger assay, (2) when this procedure is used, the 5-day Hershberger assay using young mature rats, expected to be more feasible assay than the 10-day assay using peripubertal rats, is also reliable as well as the 10-day assay using peripubertal rats. Furthermore, we confirmed that male pubertal assay with use of dissection and weighing of fixed tissues also reliable.

Androgens↗

WHO Study on the reliability and validity of the alcohol and drug use disorder instruments: overview of methods and results.

The WHO Study on the reliability and validity of the alcohol and drug use disorder instruments in an international study which has taken place in centres in ten countries, aiming to test the reliability and validity of three diagnostic instruments for alcohol and drug use disorders: the Composite International Diagnostic Interview (CIDI), the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) and a special version of the Alcohol Use Disorder and Associated Disabilities Interview schedule-alcohol/drug-revised (AUDADIS-ADR). The purpose of the reliability and validity (R&V) study is to further develop the alcohol and drug sections of these instruments so that a range of substance-related diagnoses can be made in a systematic, consistent, and reliable way. The study focuses on new criteria proposed in the tenth revision of the International Classification of Diseases (ICD-10) and the fourth revision of the diagnostic and statistical manual of mental disorders (DSM-IV) for dependence, harmful use and abuse categories for alcohol and psychoactive substance use disorders. A systematic study including a scientifically rigorous measure of reliability (i.e. 1 week test-retest reliability) and validity (i.e. comparison between clinical and non-clinical measures) has been undertaken. Results have yielded useful information on reliability and validity of these instruments at diagnosis, criteria and question level. Overall the diagnostic concordance coefficients (kappa, kappa) were very good for dependence disorders (0.7-0.9), but were somewhat lower for the abuse and harmful use categories. The comparisons among instruments and independent clinical evaluations and debriefing interviews gave important information about possible sources of unreliability, and provided useful clues on the applicability and consistency of nosological concepts across cultures.

Adult↗

Reproducibility of optical biometry using partial coherence interferometry : intraobserver and interobserver reliability.

PURPOSE: To evaluate the intraobserver and interobserver variability in axial length (AL), anterior chamber depth (ACD), and corneal radius measurements using an optical biometry instrument based on partial coherence interferometry (PCI). SETTING: Johannes Gutenberg University, Mainz, Germany. METHODS: In this observational case series and interobserver reliability trial, 30 healthy, emmetropic to moderately myopic eyes of 15 volunteers were evaluated. The AL, ACD, and corneal radius were measured 20 times in 10 eyes by 1 observer to evaluate the intraobserver variability. To evaluate the interobserver variability, the measurements were taken in 20 eyes by 5 different observers. Measurements were performed using the IOLMaster (Carl Zeiss) based on PCI. The data description is based on coefficients of variation and the statistical inference on reliability estimation based on analysis of variance. The main outcome measures were intraobserver and interobserver variability and reliability in AL, ACD, and corneal radii. RESULTS: The intraobserver variability (SD) was +/-25.6 microm for AL, +/-33.4 microm for ACD, and +/-12.9 microm for corneal radius. The coefficients of variation were 0.1%, 0.9%, and 0.17%, respectively. The interobserver variability (SD) was +/-21.5 microm for AL, +/-29.8 microm for ACD, and +/-15.9 microm for corneal radius. The coefficients of variation were 0.09%, 0.82%, and 0.21%, respectively. The reliability was 99.9% for AL, 97.8% for ACD, and 99.8%/99.5% for corneal radius (r1/r2). The slightly reduced reliability in ACD measurement was caused by a reduced intraobserver reliability of 1 of the 5 observers (R = 0.87). CONCLUSION: Partial coherence biometry using the IOLMaster for AL measurement was highly reliable, offering observer-independent measurement results.

Adult↗

Reliability of blood pressure, heart rate, and Doppler-derived hemodynamic measurements during exercise.

Doppler echocardiography of aortic blood flow, heart rate, and blood pressure represent noninvasive methods for evaluation of the hemodynamic effects of pharmacologic agents or other stimuli during rest and exercise. In this study the reliability of continuous-wave Doppler echocardiography for detecting the effects of various interventions on left ventricular systolic function during exercise was assessed. The reliability of Doppler measurements was compared with that found for measurements of simultaneously obtained heart rate and blood pressure. Exercise treadmill testing was performed at 0, 2, 4, 6, and 8 hours in 18 healthy male subjects. All measurements were performed at rest and during the last half of each exercise stage. Reliability of peak modal velocity, peak aortic blood flow acceleration, heart rate, and blood pressure was measured by the intraclass correlation coefficient (ICC) at each stage. ICC reliability of greater than 0.75 is considered excellent, 0.4 to 0.75 fair to good, and less than 0.4 poor. The reliability of all Doppler-derived parameters, heart rate, and blood pressure improved with increasing stage of exercise. Peak modal velocity, peak acceleration, heart rate, and manually obtained systolic blood pressure had ICCs of 0.75 or greater by stage 3. The reliability of Doppler-derived aortic blood flow parameters was good or excellent at rest and advanced stages of exercise. Continuous-wave Doppler echocardiography is a reliable method for performing studies to assess the effects of interventions on cardiovascular function during exercise.

Adult↗

Development of a new seizure severity questionnaire: initial reliability and validity testing.

PURPOSE: This report describes the initial steps for development of a new scale to assess seizure severity as a treatment response. METHODS: Standard methodology was used to develop the test instrument. Item generation was performed by selecting items from other questionnaires, and asking patients and epileptologists about seizure components. Face and content validity were assessed in a pilot study with patients and observers. The questionnaire was formatted as a structured interview for a reliability study. Construct validity was assessed with three existing questionnaires. Inter-rater reliability and test-retest reliability were performed as two independent ratings on one day, and one re-interview. RESULTS: Based on item generation and pilot testing (33 patients, 28 observers), the Seizure Severity Questionnaire (SSQ) was organized into warning, activity-movement, and recovery (cognitive, emotional, and physical aspects) stages of seizures. Questions reviewed duration, severity, bothersomeness and overall ratings, and the most bothersome aspect of seizures. The mean SSQ Summary Score was 5.78+/-3.24, inter-rater reliability was 0.76 (N=91), and test-retest reliability was 0.74 (N=63). Construct validity showed statistically significant correlations with other scales. CONCLUSION: This study has explored the psychometric properties of the SSQ for face and content validity, inter-rater and test-retest reliability, and construct validity. The Summary Score reliably represents the major components of seizures.

Adult↗

An analysis of the reliability phenomenon in the FitzHugh-Nagumo model.

The reliability of single neurons on realistic stimuli has been experimentally confirmed in a wide variety of animal preparations. We present a theoretical study of the reliability phenomenon in the FitzHugh-Nagumo model on white Gaussian stimulation. The analysis of the model's dynamics is performed in three regimes-the excitable, bistable, and oscillatory ones. We use tools from the random dynamical systems theory, such as the pullbacks and the estimation of the Lyapunov exponents and rotation number. The results show that for most stimulus intensities, trajectories converge to a single stochastic equilibrium point, and the leading Lyapunov exponent is negative. Consequently, in these regimes the discharge times are reliable in the sense that repeated presentation of the same aperiodic input segment evokes similar firing times after some transient time. Surprisingly, for a certain range of stimulus intensities, unreliable firing is observed due to the onset of stochastic chaos, as indicated by the estimated positive leading Lyapunov exponents. For this range of stimulus intensities, stochastic chaos occurs in the bistable regime and also expands in adjacent parts of the excitable and oscillating regimes. The obtained results are valuable in the explanation of experimental observations concerning the reliability of neurons stimulated with broad-band Gaussian inputs. They reveal two distinct neuronal response types. In the regime where the first Lyapunov has negative values, such inputs eventually lead neurons to reliable firing, and this suggests that any observed variance of firing times in reliability experiments is mainly due to internal noise. In the regime with positive Lyapunov exponents, the source of unreliable firing is stochastic chaos, a novel phenomenon in the reliability literature, whose origin and function need further investigation.

Computer Simulation↗

The reliability of assessment of vibration sense.

OBJECTIVES: To assess the reliability of quantitative assessment of vibration sense with a Vibrameter type III. MATERIAL AND METHODS: We examined 111 healthy subjects (21-69 years). For intraobserver reliability, short-term (15 min between measurements) (n=11) and 24-h (n=28) reliability was tested. For interobserver reliability, a second tester performed the second measurement 15 min after the initial test (n=39). We also assessed the independent impact of effects of age, gender and height on vibration thresholds. RESULTS: In our study the intraobserver reliability is good [intraclass correlation coefficients (ICC) ranging from 0.55 to 0.99], whereas the interobserver reliability is moderate (ICC ranging from 0.32 to 0.88). Multiple linear regression analysis showed that age and--to a lesser extent--height was independently associated with the threshold values of the feet, but not with the thresholds of the hands. CONCLUSION: The use of a Vibrameter for measuring vibration thresholds in clinical practice and in multicentre studies is restricted because of the moderate interobserver reliability.

Adult↗

The reliability of observational data: I. Theories and methods for speech-language pathology.

Much research and clinical work in speech-language pathology depends on the validity and reliability of data gathered through the direct observation of human behavior. This paper reviews several definitions of reliability, concluding that behavior observation data are reliable if they, and the experimental conclusions drawn from them, are not affected by differences among observers or by other variations in the recording context. The theoretical bases of several methods commonly used to estimate reliability for observational data are reviewed, with examples of the use of these methods drawn from a recent volume of the Journal of Speech and Hearing Research (35, 1992). Although most recent research publications in speech-language pathology have addressed the issue of reliability for their observational data to some extent, most reliability estimates do not clearly establish that the data or the experimental conclusions were replicable or unaffected by differences among observers. Suggestions are provided for improving the usefulness of the reliability estimates published in speech-language pathology research.

Humans↗

The reliability of the wolf motor function test for assessing upper extremity function after stroke.

OBJECTIVE: To examine the reliability of the Wolf Motor Function Test (WMFT) for assessing upper extremity motor function in adults with hemiplegia. DESIGN: Interrater and test-retest reliability. SETTING: A clinical research laboratory at a university medical center. PATIENTS: A sample of convenience of 24 subjects with chronic hemiplegia (onset >1yr), showing moderate motor impairment. INTERVENTION: The WMFT includes 15 functional tasks. Performances were timed and rated by using a 6-point functional ability scale. The WMFT was administered to subjects twice with a 2-week interval between administrations. All test sessions were videotaped for scoring at a later time by blinded and trained experienced therapists. MAIN OUTCOME MEASURE: Interrater reliability was examined by using intraclass correlation coefficients and internal consistency by using Cronbach's alpha. RESULTS: Interrater reliability was.97 or greater for performance time and.88 or greater for functional ability. Internal consistency for test 1 was.92 for performance time and.92 for functional ability; for test 2, it was.86 for performance time and.92 for functional ability. Test-retest reliability was.90 for performance time and.95 for functional ability. Absolute scores for subjects were stable over the 2 test administrations. CONCLUSION: The WMFT is an instrument with high interrater reliability, internal consistency, test-retest reliability, and adequate stability.

Adolescent↗

Reliability of cervical range of motion using the OSI CA 6000 spine motion analyser on asymptomatic and symptomatic subjects.

Cervical range of motion (ROM) is evaluated in both clinical and research settings. This study's purpose was to determine if ROM data obtained with the OSI CA 6000 Spine Motion Analyser (SMA) from asymptomatic and symptomatic cervical subjects were reliable within and between testers. Cervical ROM was measured in all three planes in 30 adult asymptomatic and 20 adult symptomatic subjects. A standardized protocol was used to fit each subject with the OSI SMA cervical hardware. Subjects were tested in a seated position with the trunk stabilized. Subjects performed four trials of each pain-free cervical motion during testing. The hardware was completely removed and replaced by the same tester and ROM trials in all three planes were repeated for intratester asymptomatic and symptomatic reliability. The same procedure was completed by a second tester for asymptomatic intratester and intertester reliability. Repeated measures analysis of variance and intraclass correlation coefficients (ICC [2,1 and 2 k]) were used to analyse intra- and intertester reliability data. Intratester ICCs were 0.85 or higher (except for flexion 0.76) for asymptomatic subjects and 0. 87 or higher (except for flexion 0.68) for symptomatic subjects for all motions. Intertester ICCs were 0.88 or higher for all motions. Standard error of measurements were less than 3.92 degrees for all motions. Measures of cervical spinal ROM obtained with the OSI SMA showed good intertester reliablity for all motions, and good intratester reliability for all motions with the exception of the motion of flexion for one of the examiners, which showed moderate reliability.

Adult↗