Pleomorphic adenoma of the larynx: a case and review of the literature in Japan.
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The clinical and histological features of a canalicular adenoma occurring in the palatal mucosa of a 79-year-old male are described. The management of the case-prompt referral to a specialist centre, histological confirmation of complete excision and an uneventful postoperative course-illustrates the correct procedures for what may be regarded as a cure of this neoplastic disease.
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The incidence and pathological features of the various tumours arising from salivary glandular tissues are described in the light of the World Health Organization classification of these tumours. The modern concepts relating to their histogenesis are outlined and some of the difficulties which may be encountered in their histological diagnosis are also discussed.
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The recently described hyalinizing clear cell carcinoma of salivary tissues joins other clinicopathologic entities in its segregation from the formerly nondescript and heterogeneous classification "clear cell neoplasms." The carcinoma is preponderantly an intraoral (palate and base of tongue) neoplasm that is always infiltrative and capable of regional lymph node metastasis. To date, it has responded to locoregional control treatments and has not been life-consuming.
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