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At least 217 records · Page 12Linked to original sources
PubMed1986

The influence of jaw position and antagonistic tooth relations on the appearance of a short-latency excitatory reflex in the human masseter muscles following mechanical tooth stimulation.

Post-stimulus electromyographic complexes (PSEC) were elicited by standardized tapping of a central upper incisor in 12 subjects during isometric voluntary biting in two positions, the incisor edge-to-edge (IEE) or the maximal occlusion (MO). In IEE a short latency excitatory peak (P wave) was present in the PSEC; this was absent in MO. By superimposing the rough EMG sweeps without full-wave rectification, it appeared that this P wave was brought about by synchronous masseter motor-unit firing.

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PubMed1992

The effects of colony-stimulating factor-1 on tooth eruption in the toothless (osteopetrotic) rat in relation to the critical periods for bone resorption during tooth eruption.

The toothless (tl) rat is an osteopetrotic mutation characterized by a generalized skeletal sclerosis, reduced bone resorption, few osteoclasts and a total absence of erupted teeth. This mutation is not cured by bone marrow transplants from normal littermates. It is known that the skeletal defects in tl rats are greatly improved after treatment with colony-stimulating factor-1 (CSF-1). This investigation concerns the effects of CSF-1 on the development and eruption of the dentition of tl rats. Untreated tl rats had no erupted teeth by 56 days after birth, and the roots of incisors and molars were severely distorted by compression against bone. The apex of the mandibular incisor did not extend past the first molar and continued growth of its apical end produced odontoma-like masses consisting of distorted dentine and enamel matrices. In addition, few osteoclasts were seen on alveolar bone surfaces surrounding the developing teeth. Mutants given CSF-1 were characterized by delayed eruption of all molars and sometimes incisors. The incidence of incisor eruption was related inversely to the age at which CSF-1 treatment began. Molars of treated tl rats had well-developed roots similar to those in normal rats. Treated mutants had numerous osteoclasts in alveolar bone and well-developed haemopoietic marrow spaces in the mandible. Histochemical staining for both tartrate-resistant acid phosphatase and tartrate-resistant acid ATPase was reduced or negligible in osteoclasts of untreated tl rats, heavy in normal osteoclasts and of intermediate intensity in CSF-1-treated mutants.(ABSTRACT TRUNCATED AT 250 WORDS)

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