PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Tuberculosis, Splenic”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 217 records · Page 12Linked to original sources
PubMed2004

[Portal and splenic veins thrombosis reveling a miliary tuberculosis of the liver].

The etiologies of the portal vein trombosis are dominated by the neoplasic forms with hepatocellular carcinoma; we report a rare case of portal and splenic veins thrombosis revealing a liver military tuberculosis occuring in a HIV 1 infected patient. A 42 years old senegalese woman with no personal or family history of thrombosis was admitted for abdominal upper right quadran, and epigastric pain, with fever and important weight loss. Ultrasound identified endoluminal echogenic images in the portal and splenic veins. There were no lymph nodes or liver tumor. Evaluations of proteins C and S were normal and there was no anticardiolipin antibody. In searching the aetiology of the thrombosis, a liver biopsy was performed, and showed a miliary tuberculosis. an HIV 1 infection was later on diagnosed. The antituberculosis treatment associated with heparine therapy was successful, the thrombosis resolved entirely. This portal and splenic veins thromboses occuring on a miliary tuberculosis of the liver seems to be an exceptional situation. We did not found in the literature a similar case.lt points out the interset of liver biopsy in searching the aetiology and the early heparine therapy set up

Adult↗
PubMed1995

Tuberculous splenic abscess--a case report and literature review.

Splenic involvement of tuberculosis is common, especially in cases of miliary tuberculosis. However, abscess formation due to tuberculosis in the spleen is extremely rare. We present a tuberculous splenic abscess in an otherwise healthy male patient. This patient presented with fever of unknown origin (FUO). The chest X-ray was consistent with old pulmonary tuberculosis, inactive on presentation. Due to the nonspecific clinical picture the patient remained undiagnosed until laparotomy. We have also reviewed literatures on tuberculous splenic abscess and try to make some inference about the diagnosis and treatment of this disease.

Abscess↗
PubMed1996

Accumulation of Ga-67 citrate in a tuberculous splenic abscess. Report of a rare case.

A case of 65-year-old man with tuberculous splenic abscess is presented. The Ga-67 citrate scan revealed three focal areas of increased uptake in the left upper quadrant of the abdomen. The combined Tc-99m SC/Ga-67 scans revealed that these Ga-67 avid lesions localized in the splenic photon-deficit areas found in the Tc-99m SC scan. This case demonstrated the usefulness of Ga-67 imaging in a survey of fever of unknown origin in unsuspected tuberculous splenic abscess.

Abscess↗
PubMed2001

Isolated tubercular splenic abscess.

Splenic abscess due to tuberculosis is extremely rare in immunocompetent individuals. We report a case of tubercular splenic abscess (TSA) in an immunocompetent individual for its rarity.

Abscess↗
PubMed1991

Case report: Tuberculous hepatic and splenic abscess.

Tuberculous abscess of the liver is rare and delay in diagnosis is common. The case of a 66-year-old Singaporean Chinese female with tuberculous liver abscess is reported. The abscess had an unusual septated ('honeycomb-like') ultrasonographic and computed tomographic appearance and the diagnosis was made with difficulty from material aspirated from the hepatic lesion.

Abscess↗
PubMedDate not supplied

Disseminated mycobacterial infection in AIDS patients: abdominal US features and value of fine-needle aspiration biopsy of lymph nodes and spleen.

BACKGROUND: We evaluated the efficacy of abdominal ultrasound (US) and fine-needle aspiration biopsy (FNAB) in the diagnosis of disseminated mycobacteriosis (DM) in acquired immunodeficiency syndrome (AIDS). METHODS: Twelve AIDS patients (nine male, three female; age range, 22-43 years) with DM underwent abdominal US within 2 days after admission with 3.5- to 5-MHz convex probes and a 7.5-MHz linear probe. All patients underwent FNAB of one or two enlarged abdominal lymph nodes. Eight patients underwent FNAB of the spleen. The aspirated specimens were stained with acid fast for quick examination and cultured for isolation of mycobacteria. RESULTS: Abdominal US showed enlarged, hypoechoic, round or oval, abdominal lymph nodes (diameter, 10-35 mm; mean, 18 mm) in all patients; splenomegaly (spleen diameter, 14-22 cm; mean, 16.8 mm) in all patients; numerous splenic abscesses (diameter, 3-20 mm) in nine patients; hepatomegaly (right hepatic lobe thickness, 14.5-17 cm) in all patients; small intestinal wall thickening in five patients (maximum bowel wall thickness, 7-15 mm); mild to moderate ascites in six patients; pleural effusion in four patients; bilateral enlargement of the kidneys with hyperechogenicity of the cortex in three patients; and a retroperitoneal tubercular abscess in one patient. No complication occurred after FNAB of lymph nodes and spleens. Fast-acid stain of spleen and/or lymph node FNAB specimens allowed early diagnosis of mycobacteriosis in 12 of 12 cases (100%). Cultures of lymph node aspirates grew mycobacteria in six of 12 patients (50%). Spleen aspirates grew mycobacteria in nine of nine patients (100%). Blood cultures were positive in four of 12 patients (33%). Mycobacterium tuberculosis was diagnosed in six patients and M. avium in five. CONCLUSION: Abdominal US features can suggest DM in AIDS patients. Spleen and/or lymph node FNAB indicated the specific diagnosis in 100% of patients.

AIDS-Related Opportunistic Infections↗
PubMed1971

Behavior of attenuated mycobacteria in organs of neonatal and adult mice.

The consequences of Calmette-Guérin bacillus (BCG) vaccination were followed in newborn and adult mice. BCG failed to multiply in the organs of adult mice when administered peritoneally. In contrast, extensive multiplication of the vaccine occurred in both splenic and pulmonary tissue after its peritoneal administration to newborn mice. This absence of tuberculostasis occurred during the period when the animal's spleen, lung, and thymus were rapidly growing. Animals achieved similar levels of resistance to virulent respiratory challenge 10 wk after vaccination irrespective of whether the vaccine had been administered when the mice were newly born and BCG had multiplied in vivo or administered when the animals were fully grown and the BCG had remained in the dormant state. Although neonatal infection with BCG was severe, as shown by the large numbers of organisms recovered from the animals' tissues, the animals suffered no mortality or overt signs of disease. Neonatal vaccination did not significantly affect either the animal's growth rate or the gross development of its organs.

Aerosols↗
PubMed2004

The pattern of indications and complications of splenectomy in Eastern Saudi Arabia.

OBJECTIVE: The indications for splenectomy have changed over the past decade. Trauma and hematological diseases are emerging as common indications since the early eighties of the last century. This study looks at the pattern of indications and complications of splenectomy at Dammam Central Hospital, Dammam, Eastern Province, Kingdom of Saudi Arabia. METHODS: A retrospective study of all patients who underwent splenectomy at Dammam Central Hospital over the 5-year period (1996-2000). RESULTS: There were 55 patients (47 males and 8 females) who underwent splenectomy over the study period. The mean age was 57.5 (range 4-65) years. The most common indication was trauma (43.6%) followed by hematological reasons (25.5%), which were mainly in sickle cell disease (SCD) patients (N=9). Splenic sequestration crises were the most common indication in SCD patients (77.7%). The mean weight of the excised spleen was 882.7 (range 85-1350) grams. There were 16 (29%) postoperative complications mostly encountered in patients with portal hypertension (46.2%). There were 2 deaths (3.6%) as a result of pulmonary embolism in a trauma patient and multi-organ failure in SCD. There was no reported postsplenectomy sepsis after a follow-up period of 18-72 months. CONCLUSION: The most common indication for splenectomy in Dammam is abdominal trauma, followed by hematological diseases. Splenectomy in adult SCD population is uncommon. Conventional splenectomy has 29% complication rate especially in patients with portal hypertension. This calls for rapid introduction of minimally invasive approach to reduce the morbidity associated with open splenectomy.

Adolescent↗