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[Microsurgical reconstruction of incompetent femoral vein valve in varicose disease].

We report here the results of examination and treatment of 2.178 patients with clinical class 3-6 varicose disease (CEAP). Comprehensive examination of the patients included Doppler ultrasonography, duplex scanning of the lower limbs veins with dynamic and energy mapping, retrograde femoral videophlebography, and intraoperative the test. Based on the findings of the examination, insufficiency of the femoral vein valve was revealedin 1.357 (62.3%) patients. The authors determined the indications for and contraindications to correction of valvular insufficiency in varicosity of the lower extremities, having performed a total of 1.168 microsurgical reconstructions of the femoral venous valve according to own methodology. There were neither any thromboses of the reconstruction zone observed, nor were any lethal outcomes noted to ensue. The obtained intraoperative outcomes were assessed as good in 722 patients (61.8%), as satisfactory in 427 (36.6%), and as poor in 19 (1.6%). During the early postoperative period, good short-term outcomes were observed in 972 patients (83.2%), satisfactory in 177 (15.2%), and unsatisfactory in 19 patients (1.6%).

Femoral Vein↗

Effect of the two-wall-stitch mistake upon patency of rat femoral vein anastomosis: Preliminary observations.

Anastomotic patency is believed to be the most important factor in microvascular surgery. The two-wall stitch is a technical error commonly considered to cause thrombosis of the anastomosis, especially on the venous side. In order to demonstrate the real effect on vein patency of the two-wall stitch, the authors performed a standardized mistake after correct microanastomosis on the femoral vein of 15 rats, with one stitch passing through the whole thickness of the two walls of the vein. Traditional correct anastomoses on the contralateral side were used as controls. Patency was assessed at 5, 20, and 60 min and at 24 h by the milking test, and by direct section of the vessel at 24 h. The results showed no statistically significant difference between the two techniques. Histological examination confirmed the clinical judgment about the vessel's patency, and ultrastructural microscopy evidenced only mild signs of endothelial activation. In conclusion, this study indicates that the occasional two-wall stitch does not necessarily increase the risk of venous occlusion in anastomoses of the rat femoral vein.

Anastomosis, Surgical↗

Management of recurrent superior vena caval syndrome with an externally supported femoral vein bypass graft.

Management of superior vena caval syndrome with an autogenous vein bypass graft can be complicated by occlusion of the bypass graft. The case of a patient with recurrent superior vena caval syndrome due to occlusion of a spiraled saphenous vein graft who was managed with a femoral vein graft supported externally by a sleeve of ringed polytetrafluoroethylene is presented. A venogram demonstrated patency of the graft 11 months postoperatively, and the patient remains free from clinically apparent superior vena caval obstruction 18 months postoperatively.

Adult↗

Liver biopsy through the femoral vein.

A technique to perform a liver biopsy through the femoral vein with the Mansfield biopsy forceps is described. Nine liver biopsy procedures were performed in seven patients who were considered at high risk of bleeding, precluding a conventional transperitoneal biopsy. The technique is an easy, safe, and well-tolerated procedure and is an alternative to the traditional transjugular approach.

Biopsy, Needle↗

Complications of percutaneous femoral vein catheterizations for hemodialysis.

Five life threatening complications of percutaneous femoral vein catheterization for hemodialysis (Shaldon Technique) are presented. They occurred over a period of five years during which 700 uneventful catheterizations were carried out. In three instances femoroiliac vein thrombosis occurred, and on one occasion this was complicated by pulmonary embolism. In two other instances perforation of the inferior vena cava occurred with profuse bleeding. These complications can be aboided by early removal of the catheters after dialysis and by cautiously manipulating the wireguide when resistance or obstruction is encountered during insertion.

Adult↗

[Quality of life after superficial femoral vein harvest for infra-inguinal reconstructions].

BACKGROUND: The superficial femoral vein (SFV) is a well-established alternative conduit for infra-inguinal reconstructivenous hypertension after SFV harvest may however result in significant morbidity. This study reports the efficiency of SFV as conduit for infra-inguinal reconstructions and characterize the anatomic and physiologic changes in harvest limbs and their relationship to the development of venous complications. METHODS: From May 1999 through November 2003, 23 SFV were harvested from 21 patients undergoing infra-inguinal reconstructions. Bypasses were controlled by regular duplex-ultrasound. The venous morbidity was assessed by measurements of leg circumferences, strain-gauge plethysmography and quality of life, investigated by the VEINES-QOL scale. RESULTS: At a mean follow-up of 10.4 months (range 1-56), primary, secondary patency and limb salvage rates of infra-inguinal bypasses using SFV are 71.4%, 76.2% and 85.7% respectively. No patient had major venous claudication. Oedema was significantly present in nine patients. Strain-gauge plethysmography showed outflow obstruction in all patients. The VEINES-QOL assessment showed no limitation in social and domestic activity, moderate complain about leg heaviness despite presence of oedema. CONCLUSION: The SFV harvest is a reliable conduit for infra-inguinal reconstructions and results in moderate venous morbidity in terms of functional consequences and quality of life.

Aged↗

Dual-lumen femoral vein catheterization as vascular access for hemodialysis--a prospective study.

Prospectively from January 1991 to January 1993, the efficacy and complications of 104 polyurethane, double-lumen femoral vein catheterizations (FVC) in 96 renal failure patients were studied. Ambulation was allowed in the hospital as well as at home while the catheter was in. There were 53 males and 43 females, with ages ranging from 13 to 87 (mean, 48.3 +/- 19.7) years. Forty-eight patients had chronic renal failure and 48 had acute renal failure. The catheters were used for 1 to 26 days (mean, 8 +/- 5 days). Fifty-two (50%) of the FVC were used for 2 weeks and 14 (13.5%) for 3 weeks or longer. The various complications encountered were infection (n=31), poor blood flow (n=8), displaced catheter (n=6), thrombosis of the catheter (n=4), hematoma (n=4), bleeding (n=3), exit site infection (n=3), ileofemoral vein thrombosis (n=2), and tear in the catheter wall (n=2). On removal, bacterial colonization was present in 34 out of 93 catheter tips (36.5%); Staphylococcus epidermidis (n=12) was the commonest organism grown. There was no significant difference of infection between diabetic and nondiabetic chronic renal failure patients. The duration of catheterization was found to have no relation with either thrombosis or infection. Femoral vein catheters can be used for hemodialysis for 2 to 3 weeks and ambulation during cannulation may be allowed.

Adolescent↗

Mechanism of raloxifene-induced relaxation in femoral veins depends on ovarian hormonal status.

Experiments were designed to study effects of raloxifene, a selective estrogen receptor modulator, on venous endothelium and smooth muscle. Rings of femoral veins with and without endothelium from adult gonadally intact, and ovariectomized female pigs were suspended for measurement of isometric force in organ chambers. Concentration-response curves to raloxifene (10-9-10-5 M) were obtained in rings at baseline tension or following contraction with prostaglandin (2 x 10-6 M) in the absence or presence of NG-monomethyl-l-arginine (l-NMMA) (nitric oxide synthase inhibitor), 1H-(1.2.4) oxadiazolo (4,3-A) quinoxalin-1-one (ODQ, soluble guanylate cyclase inhibitor), tetraethylammonium acetate (TEA; potassium channel blocker), or indomethacin (cyclooxygenase inhibitor). Raloxifene caused acute, concentration-dependent relaxations that were greater in rings with than in rings without endothelium from both groups. The l-NMMA significantly inhibited relaxations to raloxifene in rings with endothelium from ovariectomized females whereas TEA only inhibited relaxations in rings with endothelium from intact female pigs. ODQ and indomethacin significantly inhibited relaxations in rings with endothelium from both groups. These results suggest that raloxifene acutely relaxes femoral veins through release of endothelium-derived factors and by direct stimulation of vascular smooth muscle cells. Whether nitric oxide or potassium channel activation contributes to relaxations by raloxifene may depend on ovarian hormonal status of the animal.

Animals↗

Teaching pediatric procedures: the Vancouver model for instructing Seldinger's technique of central venous access via the femoral vein.

The way in which physicians are trained to do invasive practical procedures is an ongoing challenge for educators. Percutaneous insertion of a central line via the femoral vein using the Seldinger technique is an important practical pediatric procedure, and the need for physicians to be educated in the necessary skills is recognized in current training initiatives such as Pediatric Advanced Life Support (PALS) and Advanced Pediatric Life Support. Unfortunately, the majority of instruction in central venous access techniques is theoretic. This approach does not provide the hands-on training needed to give practitioners the necessary practical experience, or confidence in their skills. Practice using simulated tissue can enable physicians to perform practical skills with greater confidence. However, although commercially available models exist for peripheral venous access, a recent cross-Canada survey of the 13 PALS program coordinators and a similar inquiry to the American Heart Association indicated that none of them had a pediatric practice model for central venous access. We describe 1) how to construct from materials readily available a pediatric model for the insertion of central venous catheters into the femoral vein using the Seldinger technique, and 2) an evaluation of the change in confidence learning with the model engendered. In our experience, this model is inexpensive (less than $50) and can be replicated readily by others for use as a teaching aid. It provides inexperienced physicians the opportunity to learn the practical elements of the technique and acquire confidence in the Seldinger method. Our hypothesis was that the confidence and skill of physicians would be increased by practical experience of central line insertion using a realistic model. The model enables trainees to be taught the technique described in the PALS manual to locate the femoral artery. They then can learn to introduce a thin-walled needle or over-the-needle catheter, one finger's breadth below the inguinal ligament and just medial to the location of the femoral artery. The needle or over-the-needle catheter then can be advanced at the correct angle if the needle is directed toward the model's umbilicus. As occurs in vivo, the model allows for a free flow of fluid to be obtained as the "vessel" is entered. If the Foley catheter simulating the vessel is transfixed, negative pressure applied as the needle is withdrawn will result in fluid being obtained as the needle tip reenters the "vessel." The syringe then can be removed from the needle, and the key elements of the procedure-correct insertion of the Seldinger guide wire and passage of the venous catheter over the guide wire into the vessel-can be practiced. If desired, instruction also can be given on the use of a dilator and techniques of taping the catheter in place and all the appropriate techniques to avoid potential air embolism. However, the model does not lend itself to instruction in suturing. The model has been used to teach the practical elements of this technique to 428 physicians (emergency physicians, 49%; pediatricians, 24%; other physicians, 20%; pediatric residents, 7%). Their success rate for cannula insertion in three or fewer attempts was 87%. The last 218 physicians were evaluated to assess the influence of learning with the model on their confidence to perform the technique successfully in an emergency. Before training they were asked, "Have you done a pediatric resuscitation course that taught this technique in theory?" and "Rate your confidence level for performing central vascular access in a patient from 0 to 5 (none, very little, some, moderate, good, complete)." This rating was repeated after the training session using the model. For 154 (71%) answering "yes" to a previous resuscitation course, mean scores were 1.52 (standard error [SE] +/- 0.91) after theoretic instruction and 4.06 (SE +/- 0.47) after practical education using our model. The 64 (29%) physicians

Catheterization, Central Venous↗

Use of the femoral vein ('groin injecting') by a sample of needle exchange clients in Bristol, UK.

BACKGROUND: Use of the femoral vein for intravenous access by injecting drug users (IDUs) (commonly called 'groin injecting') is a practice that is often observed but on which little is written in the literature. The purpose of this study was to describe self-reported data from a sample of groin injectors on the natural history and rationale regarding their groin injecting, to inform future research and the development of appropriate harm reduction strategies. METHODS: A convenience sample of groin injectors willing to participate in a semi-structured interview were recruited through the Bristol Drugs Project Harm Reduction Service. The interviews were conducted over the period of one week. Data on transition to groin injecting, rationale for use and incidence of problems were collected. RESULTS: Forty seven IDUs currently injecting in their femoral vein ('groin') were interviewed, 66% (n = 31) male and 34% (n = 16) female. Their mean age was 31 yrs (range 17 to 50 yrs; SD = 7.7). The mean length of time since first injecting episode was 9.6 yrs (range 6 mths to 30 yrs; SD = 7.0). The mean length of time since use of the groin began was 2.6 years (range 1 mth to 15 yrs; SD = 3.3). The mean length of time between first injection and first use of the groin was 7.0 yrs (SD = 7.0). One person had used no other area for venous access prior to using the groin, nine people had used one, nine people had used two, 10 people had used three, five people had used four and 13 people had used more than four areas. The main reason given for starting to inject in the groin was that 'no other sites were left'. However further discussion identified this meant no other convenient sites were accessible. Practises such as the rotation of injecting sites, as advocated in many harm reduction leaflets, were reported to be difficult and unreliable. The risk of missing the vein and subsequently losing the 'hit' was considered high. Use of the non-dominant hand to administer injections was problematic and deterred rotation between arms. The groin site was reported to be convenient, provide quick access, with little mess and less pain than smaller more awkward veins. The formation of sinuses over time facilitated continued use of the groin. Approximately two thirds of participants had experienced difficulty gaining IV access at their groin. Common problem included scar tissue occlusion, swelling and pain. Some reported infections and past history of deep vein thrombosis. CONCLUSION: Use of the groin was perceived to be convenient by the study group. Problems following safer injecting advice were identified, including dexterity difficulties leading to fear of losing the 'hit'. Health problems at the groin site did not deter use. These results suggest further qualitative work is needed to explore the difficulties in following safer injecting advice in more detail and inform the development of more appropriate advice. Further quantitative work is necessary to establish the prevalence of groin injecting amongst IDUs and the incidence of associated problems. There is a need for a longitudinal study to examine the relationship between injecting technique and loss of patency of veins. If protective factors could be identified, evidence-based safer injecting advice could be established to preserve peripheral veins and reduce use of the groin site, which is high risk and associated with serious adverse consequences.

Journal Article↗

Contralateral femoral vein removal of a circumferentially ruptured balloon-catheter following pulmonary artery angioplasty.

While attempting to remove a circumferentially ruptured balloon following branch pulmonary artery angioplasty, the shaft of the catheter broke, leaving the distal portion of the balloon and catheter in the femoral vein but still on the exchange wire. We describe a method to retrieve the broken balloon catheter via the contralateral femoral vein.

Angioplasty, Balloon↗

Circumflex femoral vein thrombosis misinterpreted as acute hamstring strain.

The case of a 24-year-old female professional, long-distance runner who presented with acute proximal posterior thigh pain is reported. History and clinical findings were consistent with acute hamstring strain but MRI demonstrated circumflex femoral vein thrombosis. This is the first case of proximal posterior thigh pain caused by circumflex femoral vein thrombosis reported in the literature. Doctors dealing with sports injuries should be aware of this clinical entity that mimics hamstring strain.

Adult↗

Characterisation of postjunctional alpha-adrenoceptors in isolated human femoral veins and arteries.

In order to characterise the pharmacological properties of postjunctional alpha-adrenoceptors, both the contractile effects of alpha-adrenoceptor agonists and the blocking potencies of selective alpha-adrenoceptor antagonists were studied in isolated human femoral veins and arteries. The veins were more sensitive to noradrenaline than the arteries. Guanfacine had a higher intrinsic activity in veins than in arteries, whereas the reverse was true for phenylephrine. The antagonists rauwolscine and yohimbine were more potent against noradrenaline in the veins than in arteries, while corynanthine was equally potent in either tissue. They antagonised the noradrenaline response in a competitive manner. Prazosin proved to be the most potent competitive antagonist in arteries, while in veins it exerted weak and non-competitive antagonism. The results suggest that the alpha-adrenoceptor population at the postjunctional site differs between human femoral veins and arteries. The veins seem to contain more alpha 2- than alpha 1-adrenoceptors postjunctionally, whereas in the arteries the alpha 1-subtype prevails. The results indicate the possibility of influencing selectively adrenergic reactions in the capacitance and resistance vessels.

Adrenergic alpha-Agonists↗

Cystic myxomatous degeneration of the femoral vein.

We present a case of cystic myxomatous degeneration of the femoral vein. The features are similar to those found in the equivalent disease of arteries. It is suggested that it may occur in veins as an unusual and rare late sequel of venous thrombosis and recanalisation. A search of the literature has revealed only one previously reported case.

Femoral Vein↗

Duration of clinical effects and absence of referred hyperalgesia after femoral vein cannulation in rats.

The goal of this study was to assess the duration of pain-related clinical effects and referred hyperalgesia after surgery in rats. Isoflurane anesthesia with or without femoral vein cannulation was performed (n = 6 per group). Body weight and food and water consumption were monitored daily for 48 h, and tail-flick latency was measured twice daily for 24 h after surgery. Water consumption at 24 h after surgery was significantly decreased in the surgical group compared with baseline values and those of the anesthesia group. Body weight change and food consumption showed nonsignificant decreases compared with baseline in both groups 24 h after the procedure. There was a trend toward decreased food consumption after surgery compared with that for the anesthesia-alone group. Tail-flick latency was nonsignificantly decreased the afternoon after surgery compared with baseline values or that after anesthesia alone. Tail-flick latency was similar to baseline and between groups 24 h after surgery. All parameters were similar between groups and compared with baseline by 48 h after surgery. Our results show some changes in postsurgical pain-related parameters only during the initial 24-h period after femoral cannulation surgery, but only the change in water consumption was significant. Although this study involved only a small number of animals, our findings suggest that femoral vein cannulation produces a less painful stimulus than that seen in studies assessing these parameters after abdominal surgery. Hyperalgesia from a distant painful stimulus could not be measured in this model by using the tail-flick assay.

Animals↗